Vulpes lagopus (Arctic fox): 121489943
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Entry
121489943 CDS
T07435
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00020
Citrate cycle (TCA cycle)
vlg00480
Glutathione metabolism
vlg01100
Metabolic pathways
vlg01200
Carbon metabolism
vlg01210
2-Oxocarboxylic acid metabolism
vlg01230
Biosynthesis of amino acids
vlg04146
Peroxisome
vlg05230
Central carbon metabolism in cancer
Module
vlg_M00009
Citrate cycle (TCA cycle, Krebs cycle)
vlg_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
121489943 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
121489943 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
121489943 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
121489943 (IDH2)
Enzymes [BR:
vlg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
121489943 (IDH2)
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Gene cluster
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
121489943
NCBI-ProteinID:
XP_041609362
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All DBs
Position
4:complement(113265369..113282161)
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AA seq
451 aa
AA seq
DB search
MAAYLRVVRSLCRASGSGPAWAAAAPTGPSLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKIIFSPKDGSGAKEWEVYNFPGGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggctgcctacctgcgggtcgtacgttctctgtgcagagcctccggctccggcccggcc
tgggccgccgcggcgcccacaggtcccagcttgcaggagcagccgcggcgccactatgct
gacaagaggattaaggtggcaaagccggtggtggagatggacggcgatgagatgaccagg
atcatctggcagttcatcaaggagaagctcatcctaccccacgtggacgtccagctcaag
tatttcgacctgggacttccaaaccgtgaccagaccaacgaccaggtcaccatagactct
gcgttggccacccagaagtacagtgtggctgtcaaatgtgccaccatcacccccgatgag
gcccgagtggaagagttcaagttgaaaaagatgtggaagagtcccaatggaaccatccgg
aacatccttggggggactgtcttccgggaacccatcatctgcaaaaacatcccacgcctc
gtccccggctggaccaagcccatcaccattggcagacatgcccacggtgaccagtacaag
gccacagacttcgtggtggaccgagctggcacgttcaagatcattttctccccaaaggat
ggcagcggtgctaaggagtgggaggtgtacaacttccccggcggcggcgtggggatgggc
atgtacaacactgacgagtcaatctcgggttttgcgcacagctgcttccagtatgccatc
caaaagaagtggcccctgtacatgagcacgaagaacaccattctgaaagcctatgacggg
cgcttcaaggacatcttccaagagatctttgagaagcactacaagaccgactttgacaag
aataagatctggtatgagcaccggctcattgacgacatggtggctcaggtcctcaagtct
tcaggcggctttgtgtgggcctgcaagaactacgatggggatgtgcagtcggacatcctg
gcccagggctttggctcccttggcctgatgacatctgtgctggtatgccccgatgggaag
accatcgaggctgaggctgctcatggaacggtaacccgccattatcgggagcaccagaag
ggccggcctaccagcacgaaccccattgccagcatctttgcctggacacgcggcctggag
caccgggggaagctggatgggaaccaggacctcatcaggtttgcgcagaccctggaaaaa
gtgtgtgtccagactgtggagagtggagccatgaccaaggacctggcaggctgtatccat
ggcctcagcaacgtgaagctgaacgagcacttcctgaacacctccgacttcctggacacc
atcaagaacaacctggacaaggctctgggccagtag
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