Vulpes lagopus (Arctic fox): 121490029
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Entry
121490029 CDS
T07435
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg01521
EGFR tyrosine kinase inhibitor resistance
vlg01522
Endocrine resistance
vlg04010
MAPK signaling pathway
vlg04014
Ras signaling pathway
vlg04015
Rap1 signaling pathway
vlg04066
HIF-1 signaling pathway
vlg04068
FoxO signaling pathway
vlg04081
Hormone signaling
vlg04114
Oocyte meiosis
vlg04140
Autophagy - animal
vlg04144
Endocytosis
vlg04150
mTOR signaling pathway
vlg04151
PI3K-Akt signaling pathway
vlg04152
AMPK signaling pathway
vlg04211
Longevity regulating pathway
vlg04213
Longevity regulating pathway - multiple species
vlg04510
Focal adhesion
vlg04520
Adherens junction
vlg04550
Signaling pathways regulating pluripotency of stem cells
vlg04730
Long-term depression
vlg04913
Ovarian steroidogenesis
vlg04914
Progesterone-mediated oocyte maturation
vlg05200
Pathways in cancer
vlg05202
Transcriptional misregulation in cancer
vlg05205
Proteoglycans in cancer
vlg05214
Glioma
vlg05215
Prostate cancer
vlg05218
Melanoma
vlg05224
Breast cancer
vlg05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121490029 (IGF1R)
04014 Ras signaling pathway
121490029 (IGF1R)
04015 Rap1 signaling pathway
121490029 (IGF1R)
04066 HIF-1 signaling pathway
121490029 (IGF1R)
04068 FoxO signaling pathway
121490029 (IGF1R)
04151 PI3K-Akt signaling pathway
121490029 (IGF1R)
04152 AMPK signaling pathway
121490029 (IGF1R)
04150 mTOR signaling pathway
121490029 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
121490029 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
121490029 (IGF1R)
04140 Autophagy - animal
121490029 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
121490029 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
121490029 (IGF1R)
04520 Adherens junction
121490029 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
121490029 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
121490029 (IGF1R)
04914 Progesterone-mediated oocyte maturation
121490029 (IGF1R)
09156 Nervous system
04730 Long-term depression
121490029 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
121490029 (IGF1R)
04213 Longevity regulating pathway - multiple species
121490029 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121490029 (IGF1R)
05202 Transcriptional misregulation in cancer
121490029 (IGF1R)
05205 Proteoglycans in cancer
121490029 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
121490029 (IGF1R)
05214 Glioma
121490029 (IGF1R)
05218 Melanoma
121490029 (IGF1R)
05215 Prostate cancer
121490029 (IGF1R)
05224 Breast cancer
121490029 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121490029 (IGF1R)
01522 Endocrine resistance
121490029 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vlg01001
]
121490029 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
vlg04090
]
121490029 (IGF1R)
Enzymes [BR:
vlg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
121490029 (IGF1R)
Protein kinases [BR:
vlg01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
121490029 (IGF1R)
CD molecules [BR:
vlg04090
]
Proteins
121490029 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
121490029
NCBI-ProteinID:
XP_041609516
LinkDB
All DBs
Position
4:101941355..102245606
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
RRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRL
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgttcttctcc
gccgcgctgtcgctctggccgacgagtggagaaatctgtgggccgggcatcgacatccgc
aatgactatcagcagctgaagcgcctggagaactgtacagtgatcgagggctacctccac
atcctactcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgtgtggccggccttgagagcctcggggatctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaacctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaacgctgacctctgttacctctccacagtggactggtccctgatc
ctggatgcagtatccaacaactacattgtggggaacaaacccccgaaggaatgtggggac
ctgtgtccagggacaatggaggagaagcccttgtgcgagaagactaccatcaacaatgaa
tacaactatcgctgctggactacaaatcgctgccagaaaatgtgcccgagcgcttgcggg
aagcgggcgtgcacggagaacaacgagtgttgtcaccccgagtgtctgggcagctgcagc
gcaccggacaacgatacggcctgtgtggcctgcaggcattactactacgcaggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgac
ggcgagtgcatgcaggagtgtccctctgggttcatccgcaatggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgtcccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgtaccatcttcaagggcaatttg
ctcattaatatccgccgaggcaataacattgcctcagagctggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttggtctccctgtcc
ttcctaaaaaaccttcgccagatcttaggagaggaacagctggaggggaactactccttc
tacgtcctcgacaaccagaacttgcagcagctttgggattgggaccaccgtaacctgacc
atcaaagctgggaaaatgtattttgctttcaatcccaaattgtgcgtctccgaaatttac
cgcatggaagaagtgacggggaccaaaggacgccagagcaaaggagacataaataccaga
aacaatggagagcgagcctcctgtgaaagcgacgtcctgcacttcacctctacgaccaca
tggaagaatcgcatcatcatcacgtggcaccgttaccggccccctgactacagggacctc
atcagctttactgtctactacaaggaagcaccttttaaaaacgtcacggagtatgatggg
caggatgcctgtggctccaacagctggaatatggtagatgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcatggactgaagccctggacgcagtatgcggtttat
gtcaaggcggtgaccctcaccatggtggagaatgaccacatccgtggggctaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttctgcg
tcaaactcctcttctcagctcattgtgaagtggaacccaccctctctgcccaacggtaac
ctcagttactacatcgtgaggtggcagcggcagccccaggacagttacctttaccgccac
aactactgctccaaagataaaatccccatcaggaagtatgctgatggcaccattgatgtc
gaagaggtgacagagaatcccaagaccgaagtatgtggtggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggctgagaaggaggaggccgagtaccgcaaa
gtgttcgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaaacgtaga
gatgttacacaagtcaccaacaccaccatgtccagccgaagcaggaacaccacggtggtg
gacacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttaccctgtaccgc
attgacatccacagctgcaatcatgaggctgagaagctgggctgcagtgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcccaaatcgaggatcagcgggaatgtgta
tccagacaggagtacaggaagtatggaggtgccaagcttaaccggctcaacccggggaac
tatacagcccggatccaggccacttctctctctgggaatgggtcgtggacggatcctgtg
ttcttctatgtcccagccaaaataacgtatgaaaacttcatccatctgatcattgctctg
cccgttgctgtgctattgatagtgggagggttggttataatgctgtacgtcttccacagg
agaagaaataacagcaggctggggaatggagtgctgtatgcttccgtgaacccagaatac
ttcagtgctgccgatgtgtatgtacctgatgagtgggaggttgctcgagagaagatcacc
atgagccgagagctgggccagggctcgtttggaatggtatatgaaggagttgccaagggt
gtggttaaagatgagcctgaaacaagggtggccattaaaacagtgaacgaggctgccagc
atgcgtgaaaggatcgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacacgaggggatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctcgcacctccaagcctaagcaagatgatccagatggctggggagattgct
gatggcatggcatacctcaacgccaacaagttcgtccacagagaccttgctgccaggaac
tgcatggtggccgaagatttcacagtcaaaattggagatttcggtatgacaagagacatc
tatgagacagactattaccggaaaggaggcaaggggctgctgcctgtgcgctggatgtca
cctgagtctctcaaggatggagtcttcaccactcactctgacgtctggtcctttggggtc
gttctctgggagatcgccacgctggctgagcagccataccagggcttgtccaacgagcaa
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagccggagaacatg
gagagtgtccccctggacccttcggcctcctcgtcgtccctgcctctgcctgacagactc
tcaggacacaaggccgagaacggcccaggccctggcgtgctggttctgcgagccagcttc
gatgagagacagccttacgcgcacatgaacgggggccgcaagaacgagcgggccttgcct
ctgccccagtcttcaacctgctga
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