KEGG   Vulpes lagopus (Arctic fox): 121491443
Entry
121491443         CDS       T07435                                 
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
vlg  Vulpes lagopus (Arctic fox)
Pathway
vlg00260  Glycine, serine and threonine metabolism
vlg00630  Glyoxylate and dicarboxylate metabolism
vlg00670  One carbon pool by folate
vlg01100  Metabolic pathways
vlg01200  Carbon metabolism
vlg01230  Biosynthesis of amino acids
vlg01240  Biosynthesis of cofactors
vlg01523  Antifolate resistance
vlg04981  Folate transport and metabolism
Module
vlg_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:vlg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    121491443 (SHMT2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    121491443 (SHMT2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    121491443 (SHMT2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    121491443 (SHMT2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    121491443 (SHMT2)
Enzymes [BR:vlg01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     121491443 (SHMT2)
SSDB
Motif
Pfam: SHMT Aminotran_1_2
Other DBs
NCBI-GeneID: 121491443
NCBI-ProteinID: XP_041612300
LinkDB
Position
5:complement(68257406..68262366)
AA seq 505 aa
MLPFSLLWATRPLQRCGRLVRVASRCQHSEVAQAQTREAASRGWTGQESLSDSDPEMWEL
LQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLC
QRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSD
VKRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMRE
VCDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGTRAM
DPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPTFREYALQVLKNAR
AMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAI
TPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVQIGLEVKNKTAKLQDFKSFLLKDSETS
HRLADLRQRVEQFARAFPMPGFDER
NT seq 1518 nt   +upstreamnt  +downstreamnt
atgctgcccttctctttgctttgggccactcggcctctgcagagatgtgggcggctggtc
agggtggcctcccggtgccagcacagcgaggtggcccaggcccagaccagagaagcggcg
agcaggggctggacgggccaggagagtctgtcagacagtgatcctgagatgtgggagctg
ctgcagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttc
tgcagccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggt
tatcctggcaagagatactatggaggagccgaggtagtggatgaaattgagctgctgtgt
cagcgcagagccctggaggcctttgacctggatcctgcacagtggggagtcaacgtccag
ccctactcaggctctcccgctaatctggccgcctacacagccctcctgcagcctcatgac
cgaatcatggggctagacttgcccgatgggggccatcttacccatggctacatgtctgat
gtcaagcgggtctcagccacgtccatcttctttgagtccatgccctacaagctgaatcct
aaaaccggcctcatcgactatgaccagctggcactgaccgctcgacttttccggccgcgg
ctcattatagctggtaccagcgcctatgctcgcctcattgactatgcccgcatgagagag
gtgtgtgatgaggtcaaggcacacctgctggcagacatggcccacatcagtggcctggtg
gctgccaaggtgatcccctcacctttcaagcatgcggatgttgtcaccaccaccactcac
aagacccttcgaggggccaggtcaggactcatcttctaccgcaaggggacgcgggctatg
gaccccaagactggccgggagatcccttacacgtttgaggaccgaatcaactttgctgtg
ttcccatccctgcagggtgggccccacaaccatgccattgctgccgtggctgtggcccta
aagcaggcctgcacccccacattccgggagtacgccctgcaggttctaaagaatgctcgg
gccatggccgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaac
cacctagtgctagtggacctgcggcccaagggcctggacggagctcgggctgagcgggtg
ctggaactggtatccatcacagccaacaagaacacctgtcctggggaccgaagcgccatc
acacctgggggcctgcggcttggggccccagccttgacctctcgacagttccgtgaggat
gacttccggagggtcgtggactttatagatgaaggtgtccaaatcggcttggaggtgaag
aacaagaccgccaaacttcaggatttcaaatctttcctgctcaaggactcagaaacaagt
catcggctggccgacctcaggcagcgagtggagcagtttgccagggccttccccatgcct
ggttttgatgagcgctga

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