Vulpes lagopus (Arctic fox): 121491663
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Entry
121491663 CDS
T07435
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00140
Steroid hormone biosynthesis
vlg01100
Metabolic pathways
vlg05215
Prostate cancer
Module
vlg_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121491663 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
121491663 (SRD5A2)
Enzymes [BR:
vlg01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
121491663 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
PEMT
Motif
Other DBs
NCBI-GeneID:
121491663
NCBI-ProteinID:
XP_041612703
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Position
5:108877022..108917856
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AA seq
254 aa
AA seq
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MPIRCQQSPVLAGSAALAAMGALVLCLAKPSGYGKYSEGLTPAAPRLPARAAWFLQELPS
FAVPAGILARQPRALLGQPATVLLGLFCAHYFHRTFIYSLLTRGRPFPVVFLVRGFIFCA
GNGLLQGYYLIYCAEYPAEWYMDVRFSLGIFLFILGMGINIHSDYILRQLRKPGEVTYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFLF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcccattcgctgccagcagagcccggtgctggcaggcagcgccgctttggcggccatg
ggggccctggtcctgtgcctggccaagccctcgggctacgggaagtactcggagggcctg
acgcccgccgccccccgcctgcccgcgcgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgcccggcagccgcgcgctctcctcggccagcctgcg
acggtgctcctgggcctcttctgcgcgcactacttccacaggacatttatttactcattg
ctcactagagggaggccttttccagttgtgttcctggtcagaggatttatcttctgtgcg
ggaaatggacttctccaaggctactatctgatttactgtgctgagtaccctgctgagtgg
tacatggatgtgcggtttagcctgggtatcttcttatttattttgggaatgggaatcaac
attcatagtgactatatattgcgccagctcaggaagcctggagaagtcacctataggatt
ccacaaggtggcttgtttacgtatgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgccctggctacttggtccctcccagcacttgcatttgcgtttttctca
ctttgcttcctggggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaggccctcattccatttctcttttaa
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