KEGG   Vulpes lagopus (Arctic fox): 121492052
Entry
121492052         CDS       T07435                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
vlg  Vulpes lagopus (Arctic fox)
Pathway
vlg04010  MAPK signaling pathway
vlg04022  cGMP-PKG signaling pathway
vlg04137  Mitophagy - animal
vlg04141  Protein processing in endoplasmic reticulum
vlg04151  PI3K-Akt signaling pathway
vlg04210  Apoptosis
vlg04211  Longevity regulating pathway
vlg04261  Adrenergic signaling in cardiomyocytes
vlg04668  TNF signaling pathway
vlg04720  Long-term potentiation
vlg04722  Neurotrophin signaling pathway
vlg04725  Cholinergic synapse
vlg04728  Dopaminergic synapse
vlg04911  Insulin secretion
vlg04912  GnRH signaling pathway
vlg04915  Estrogen signaling pathway
vlg04918  Thyroid hormone synthesis
vlg04922  Glucagon signaling pathway
vlg04925  Aldosterone synthesis and secretion
vlg04926  Relaxin signaling pathway
vlg04927  Cortisol synthesis and secretion
vlg04928  Parathyroid hormone synthesis, secretion and action
vlg04932  Non-alcoholic fatty liver disease
vlg04934  Cushing syndrome
vlg04935  Growth hormone synthesis, secretion and action
vlg05010  Alzheimer disease
vlg05012  Parkinson disease
vlg05014  Amyotrophic lateral sclerosis
vlg05020  Prion disease
vlg05022  Pathways of neurodegeneration - multiple diseases
vlg05030  Cocaine addiction
vlg05031  Amphetamine addiction
vlg05034  Alcoholism
vlg05161  Hepatitis B
vlg05163  Human cytomegalovirus infection
vlg05166  Human T-cell leukemia virus 1 infection
vlg05203  Viral carcinogenesis
vlg05207  Chemical carcinogenesis - receptor activation
vlg05215  Prostate cancer
vlg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vlg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    121492052 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121492052 (ATF4)
   04668 TNF signaling pathway
    121492052 (ATF4)
   04022 cGMP-PKG signaling pathway
    121492052 (ATF4)
   04151 PI3K-Akt signaling pathway
    121492052 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    121492052 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    121492052 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    121492052 (ATF4)
   04922 Glucagon signaling pathway
    121492052 (ATF4)
   04912 GnRH signaling pathway
    121492052 (ATF4)
   04915 Estrogen signaling pathway
    121492052 (ATF4)
   04926 Relaxin signaling pathway
    121492052 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    121492052 (ATF4)
   04918 Thyroid hormone synthesis
    121492052 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    121492052 (ATF4)
   04925 Aldosterone synthesis and secretion
    121492052 (ATF4)
   04927 Cortisol synthesis and secretion
    121492052 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121492052 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    121492052 (ATF4)
   04728 Dopaminergic synapse
    121492052 (ATF4)
   04720 Long-term potentiation
    121492052 (ATF4)
   04722 Neurotrophin signaling pathway
    121492052 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    121492052 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    121492052 (ATF4)
   05203 Viral carcinogenesis
    121492052 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    121492052 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121492052 (ATF4)
   05161 Hepatitis B
    121492052 (ATF4)
   05163 Human cytomegalovirus infection
    121492052 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121492052 (ATF4)
   05012 Parkinson disease
    121492052 (ATF4)
   05014 Amyotrophic lateral sclerosis
    121492052 (ATF4)
   05020 Prion disease
    121492052 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    121492052 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    121492052 (ATF4)
   05031 Amphetamine addiction
    121492052 (ATF4)
   05034 Alcoholism
    121492052 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121492052 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    121492052 (ATF4)
   04934 Cushing syndrome
    121492052 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:vlg03000]
    121492052 (ATF4)
Transcription factors [BR:vlg03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    121492052 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 NAM-associated DUF4407 MCU Asd-4 KIF21A Fib_alpha DUF3450 AAA_13 Nop53 bZIP_Maf OVT1 Laminin_II
Other DBs
NCBI-GeneID: 121492052
NCBI-ProteinID: XP_041613230
LinkDB
Position
5:complement(9356742..9358865)
AA seq 349 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLALDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDTLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQIVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNSLLSPGSLCGSARPKPYDPPGEKTAKVKVEKLDKKLKKMEQNKTAATRYRQKKRAE
QEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1050 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggaaagcctaggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctttggatgggttggtcagtgcctcagacaacggcaaggaggatgccttctcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgatactctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagactaataaggagccccctcagatcgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttacctttctg
caaccacttccactctccccaggggccctgtcctccactccagatcattcctttagttta
gagctaggcagtgaagtggatatctctgaaggagatagaaagtcagattctactgcttac
attacagtgatccctcagtgcataaaggaggaagatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatcttgggtccccccagcatagcccttctacctccagg
ggctctccaaatagcttgctgtctccaggttccctctgtggttctgcccgccccaaaccc
tatgacccccctggagagaagaccgcaaaagtaaaggttgagaaactagataagaaactg
aaaaaaatggagcagaacaagacagcagccactaggtaccgccagaagaagagggcagag
caggaagccctcactggtgagtgtaaagaactggaaaagaagaacgaggctctgaaggag
agggcagattctctagccaaggagatccagtatctgaaagatttgatagaggaggtcaga
aaggccagggagaagaaaagggtcccctag

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