Vulpes lagopus (Arctic fox): 121495292
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Entry
121495292 CDS
T07435
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00230
Purine metabolism
vlg01100
Metabolic pathways
vlg04024
cAMP signaling pathway
vlg04928
Parathyroid hormone synthesis, secretion and action
vlg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121495292 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
121495292 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
121495292 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
121495292 (PDE4A)
Enzymes [BR:
vlg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
121495292 (PDE4A)
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GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
121495292
NCBI-ProteinID:
XP_041618476
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Position
7:7462908..7505394
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AA seq
870 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAAASQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREKQPSPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEEEEE
VSTAPGAFEVQGLSMAQDPSPAEDLLEADGQDMPMEVKVEEPCFTQQADSADSVAAGKDK
ARSPDASVDAVGCGGLLALSVKSPPLPALRTLPPPEEPPGLPGLPSMAAEVGAQKEQAAK
RACSACTGTSGEDPPPPPAPGGWGSAGGPT
NT seq
2613 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccctcggagaggagcctgtctctgtctctgcctgggccccgg
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgcggaccccc
attcgtatccagcagcgcggctattccgacagcgcggagcgcgcagagcccgagcggccg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttcccgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaggcgcttcgaggcagagaatgggcccacaccatctcctggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcatgctggggccgctgccagc
cagcgccgggagtccttcctgtaccgttcggacagcgactacgacatgtcccccaaaacc
atgtcacggaactcgtcagtcaccagcgaggcgcacgctgaggacctcattgtgacacct
ttcgcccaggtgctggccagcctccgaagtgttcgcagcaacttctcactcctgaccaat
gtgcccattcccagcaacaaacggtccccactgggcggcccaacccctgtctgcaaggcc
acgctgtcagaagagacatgtcagcaattggcccgggagacattggaggagctggactgg
tgtctggagcagctggagaccatgcagacctaccgttccgtgagcgagatggcttctcac
aagttcaagaggatgttaaaccgtgaacttacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaacgaagtggagatt
ccatcacccacaatgaaggatcgagaaaaacagccatccccacgtcagagaccctcccag
cagcccccgccccctgggccgcagttccagcccatgtctcagatcacaggggtgaagaaa
ctgatgcacagcagcagcctgaatgattccagcattccccgctttggggtgaagacagat
caagaggagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttc
tgcgtctcagaatatgctggagggcgttcactcagctgcatcatgtacacgatatttcag
gaacgggacctgctaaagaagttccgcatcccagtggacaccatggtgacttacatgctg
accctggaggaccactaccatcccgatgtggcttaccacaacagcttgcacgcggccgat
gtgctgcagtctacccatgtgctgctggcaacacccgcgctagatgctgtgttcacggac
ctggagatacttgcggccctcttcgcggctgccattcatgatgtggaccatcctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgatgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagacaactgtgac
atcttccagaacctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggcagacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctcctgctggacaactactctgaccgtatc
caggtccttcggaacatggtgcactgtgcagacctcagcaaccccaccaagccactggag
ctgtaccgccagtggactgaccgcatcatggccgagttctttcagcagggtgaccgtgaa
cgtgagcggggcatggagatcagccccatgtgcgacaagcacacagcctcggtagagaag
tctcaggtgggtttcatcgactatattgtacacccgctgtgggagacgtgggctgacctg
gtccatccagatgcacaggagatcctggacacattggaggacaaccgggactggtactac
agtgccattcggcagagcccgtcaccaccgccagaagaggagccaagagggccaggccac
ccacccccacctgataagttccaatttgagctgacactggaggaggaagaggaggaggag
gtgtctactgccccaggtgcattcgaagtacagggattgtccatggctcaggatccgtcc
ccagccgaggacctgttggaggctgatggccaggatatgcccatggaggtgaaggtagag
gaaccgtgcttcacacagcaagcagactcagcagatagtgtggctgcaggcaaggacaag
gccaggtccccagatgcatccgtggatgccgtgggctgtggtggcctcctggccctgtct
gtcaagagcccccctctgcctgctttgaggaccctgccccctccagaggaacccccgggc
ctcccgggcctcccctccatggcggccgaggtgggggcccaaaaagagcaggctgccaag
agggcgtgcagtgcgtgcacaggaacatctggcgaggaccccccgccccccccagctcct
ggcgggtggggatcagccggaggtcctacctga
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