Vulpes lagopus (Arctic fox): 121495589
Help
Entry
121495589 CDS
T07435
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00310
Lysine degradation
vlg01100
Metabolic pathways
vlg05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
121495589 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
121495589 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
vlg03036
]
121495589 (DOT1L)
Enzymes [BR:
vlg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
121495589 (DOT1L)
Chromosome and associated proteins [BR:
vlg03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
121495589 (DOT1L)
HMT complexes
Dot1-containing complex
121495589 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
121495589
NCBI-ProteinID:
XP_041619243
LinkDB
All DBs
Position
7:1268875..1336187
Genome browser
AA seq
1710 aa
AA seq
DB search
MPRAGAVRWPCRVPAPCTTGGCKPCPFVFQDKHHDAAHEIIETIRWVCEEIPDLKLAMEN
YVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNH
SVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAAT
NCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSV
IFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELS
PLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPT
KVPESKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKM
STANPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLL
APTPPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQ
AQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNRELRSQSL
QLLKARCEELKLDWSTLSLENLLKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELL
QLKSCVPPDEALSAHLRGKGALGRELEADPSRLHLDLDCSKFSLPHFSSASPELSMNGHA
ANYELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRSRLEKMSGLALPDYTRLSPA
KLVLRRHLSQDHATSGKPAAGELHPRAEHTKENGLPYQSPGIANGIKLSPQDPRPSSPVA
LQMTGERGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKV
RSTPSPVPQTRESSSTLEKQMGTNTHSAGSKSLASTPAGFYTGSVAVSGALAGSPAPLAP
GAEPSAFDEVSGSGSLFASMGSCSSTPQHPPLLPQSRGSGAASPAHPLCASPRLSSVAQG
PLPDANKGDLPSEAGFSDPEGEAKRRIVFTISAGGSSAKQSPPSKPSPLPTGARGDSSQG
HGSDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPL
EITAISSPESLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSAR
IERKIATISLESKSPPKTLESGGGLAGRKPTPASEPTNSSKWKSTFSPISDLGLAKCADS
PLQAGSTLSQNSLFTFRPPLDDPGSADTKLAAHPRKSFPGALSGAGGLSPSSNPPNGFAF
GGGLAADLSLHSFSDGASLSHKVPEAASLGAPLSFPAPRGKEGGATEPGAFVNKRQLDGL
GGPKGREAGELGLPVCGPPDKASLTHSKPTKGRDREPDLKNGHNLFISAATVPPAGLLSG
PGLATVASSAVSAAPSAQTHRPFLGTFTPGPQFALGPMSLQANLGSSVLQSLFSSVPAAA
GLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSAT
LSLTPLQAVASAPASSFQAPPPPPPGQPALPAPPPPNAALPPAPALLPANSEPVLLQNLA
SLPANQAFLPASSAASLQPANASLSIKLASLPHKAPRPSFTVHHQPLPGLALAQAAPVIP
QASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5133 nt
NT seq
+upstream
nt +downstream
nt
atgccccgggccggggctgtccgttggccttgccgggtccccgcaccctgcaccactgga
gggtgtaaaccctgtccctttgtctttcaggacaaacaccacgatgctgctcatgaaatc
atcgagaccatccgatgggtctgtgaagagatcccagacctcaagcttgctatggagaat
tacgttttaatcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaaa
tacaaccgtgccatcgacagcatccaccagctgtggaaggggaccactcagcccatgaaa
ctgaacactcggccgtccaacgggctcctgaggcacatcctgcagcaggtgtacaaccac
tcggtgacggaccccgagaagctcaacaactatgagcccttctccccggaggtgtacggg
gagacctcctttgacttggtcgcacagatgattgacgagatcaagatgaccgaggatgac
ctgtttgtggacctgggcagtggagtgggccaggttgtgctgcaggtcgccgcggccacc
aactgcaaacatcactatggtgtggagaaagctgacatcccagccaagtacgcggagacc
atggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacaca
ctggaaagaggcgacttcctctcagaagagtggagagagcggattgccaacacaagtgtt
atatttgtgaataattttgcctttggtcctgaggtggatcaccagctgaaggagcggttt
gcgaacatgaaggaaggcggcagaattgtgtcctcgaagcccttcgcacctctcaacttc
cggataaacagcagaaacttgagtgacatcggcaccatcatgcgcgttgtggagctctcg
cccctgaaaggctcggtgtcctggacggggaagccggtctcctactacctgcacactatc
gaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaa
caagaggcagctcggcgccggcagcagcgagagaacaagagcaacacgaccactcccacc
aaggtgcccgagagcaaggctgctgtgcctgccgacacccctatggattctggtgccgag
gaagaaaaggctggggcaaccaccatcaaaaagccgtctccctccaaagcccggaagaag
aagctgaacaagaaggggcggaagatggccggccggaagcgtgggcgtcccaagaagatg
agcactgcgaaccccgagcgtaagcccaagaagagccaaactgcactggacctcctgcat
gcccaggccgcgtctcagacggcagcgccctcgccgcaggatgcgtacaagtcacctcat
agcccattttatcagctacctcccagtgtgcagcggcacccccctgaccagctgctgctg
gcacccaccccacccgcactgcagaagctgctagaatccttcaagattcagtacttgcag
ttcttggcgtacaccaagaccgcccagtacaaggccagcctgcagcagctgctggaccag
gagaaggagaagaacgcccggttgctaggtgctgcgcagcagctgtttggccactgccag
gcccagaaagaggagatcaagaggctcttccagcagaaactggatgagctgggagtgaag
gcgctgacctacaacgacctgattcaggcacagaaggagatctcggctcataatcagcag
ctgagggaacagacggagcagctgcagaaggacaacagggagctgaggagccagagccta
cagctgctcaaggctcggtgtgaggagctaaagctggactggtccacgctgtccctggag
aacctgctgaaggagaagcaggccctgagaagccagatctccgagaagcagaggcactgc
ctggagctgcagatcagcattgtggagctggaaaagagccagcggcagcaggagctcctg
cagctcaagtcctgtgtgcctccagatgaggccctgtcagcgcacctgcgtgggaagggc
gccctgggccgggagctggaggccgaccccagccgactgcacctcgacctggactgctcc
aagttctctctgccccacttcagcagcgcaagcccagagctctccatgaacggccacgca
gccaactacgagctctgcagcgcgctgagccggccctcatccaagcagaacacgcctcag
tacctggcctccccgctggaccaggaagtcgtaccctgcacccccagccacagcagccgg
tcgaggctcgagaagatgtctggcctggctttgcccgactacaccaggctctccccggcc
aagctggtgctgcggcgtcacctgagccaggaccacgcgaccagcggcaagccagccgcc
ggtgagctgcacccacgagctgagcataccaaggagaacggccttccataccagagccct
ggcatcgcaaacggcatcaagctgagccctcaggaccctcgaccctcgtcccccgtggcc
ttacagatgacaggagagaggggcagtgagaagggcttgaaggagcgtgcctatgccagc
agcggagaggccatcaccagcctgcctgttagcatcccgctcagcactgtgcagcccagt
aagctgcccgtcagcatccctctggccagtgtggtgctgcccagccgcgctgagaaagtg
agaagcacccccagccctgtgccgcagacccgagagtcctcgtccacacttgaaaagcaa
atgggcacaaacacccacagcgctggaagcaaaagccttgcctcaactcctgcaggcttc
tacacgggctcggtggccgtcagtggggccctggcaggcagcccagcgcccctggctcct
ggagcagagcccagcgccttcgacgaggtctctggctcaggaagcctgttcgccagcatg
gggtcctgcagctccaccccgcagcacccgcccctgctgccacagtcccgtggctccggc
gcagcctcacccgcccatccgctctgtgccagtccgcggctcagcagtgtcgcccagggc
ccgctccccgatgccaacaaaggggaccttccgtccgaggcaggcttctcagaccctgag
ggcgaagccaagaggaggattgtctttaccatctcagctggtggcagcagtgccaaacag
tcgcctcccagcaaacccagccctctgcccacgggtgcccgcggggacagcagccagggc
catgggtcggacagccgcaagcggggcaggagaaagcgggcctcggcggggaccccgagc
ctgagctcaggcgtatcacctaagcgtcgagccttgccgtccgttgccggcctcttcacg
cagtcttcagggtccccgctgaacctcaactctatggtcagcaacattaaccagcctttg
gaaatcacggccatctcgtcccccgagagcctgaagagctcccctgtcccttaccaggac
aacgaccagcctcccgttctcaagaaggagaagcccctgagccagaccaatggggcccac
tactccccactgacctcagatgaggagcagggctctgaggacgagccaggcagtgccaga
atcgagagaaaaattgcaacaatttccttagaaagcaaatcccctccaaaaaccttggaa
agcggtggtggcctggccgggaggaagccgacccctgccagcgagcccaccaacagcagc
aagtggaagtccaccttctcgcccatctccgacctcggcctggccaagtgcgctgacagc
ccgctgcaggccggctccaccctgagccagaactccctgttcactttccggcctcccctc
gatgatcccggctcggccgacaccaagctggctgcccaccccaggaaaagctttcccggc
gctctgtcgggggccggtgggctgagcccaagcagcaaccctcccaacggcttcgccttc
ggtgggggcctggccgccgacctcagtttacacagcttcagcgatggtgcttctctctcc
cacaaggtccccgaggcggccagcctgggcgcacccctgagctttcctgcccctcggggc
aaggagggcggtgccacagagcccggcgcctttgtgaacaagaggcagctggacggactg
ggcggcccgaagggcagggaggcgggcgagttgggcctgccagtgtgcgggcccccggac
aaggcctcgctgacgcacagcaagcccaccaagggccgggaccgcgagcccgacctgaag
aatggccacaacctcttcatttctgctgccaccgtgcctcccgctggcctcctcagtggc
cccggcctcgccacggtggcatcctcggcagtcagcgcggccccgtctgcccagactcac
cgccccttcctgggcaccttcacccccgggccgcagttcgccctgggtcccatgtccctg
caggccaacctgggttcgtccgtgctgcagtccttgttcagctccgtgccggctgctgct
ggcctggtgcacgtctcgtccgctgcaaccagactgaccaactcgcacgccatgggcagc
ttttcctcgggggtggcaggcggcgcagttggaggtgtctttaaccacgcggtgccttcc
gcctccgctcatccgtttggagccagtttcggcagcggggctgcgtgtcgcagcgccacg
ctgagcttaaccccgctgcaggcggtggccagcgcccccgcgtcttcctttcaggccccg
cccccgccccctccggggcagcccgccctccccgcaccccctccccctaacgccgccttg
cctcctgcccccgcgctgctcccggctaactctgagcccgtgcttctgcagaaccttgcg
tccctcccagctaaccaggctttcttacctgcctcctctgccgcctctctgcagcctgct
aacgcctctctgtccatcaagctcgcttccctcccgcacaaggccccccgcccctccttc
acggtgcaccaccagcccctgcccgggctggccctggcccaggccgcgcccgtgatcccg
caggccagctccacggggccgtctgccgtgtgggtttcccttggcatgccgcctccgtat
gccgcgcgccttgcgggggttaagccgagataa
DBGET
integrated database retrieval system
