Vulpes lagopus (Arctic fox): 121495696
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Entry
121495696 CDS
T07435
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg04217
Necroptosis
vlg04380
Osteoclast differentiation
vlg04620
Toll-like receptor signaling pathway
vlg04621
NOD-like receptor signaling pathway
vlg04630
JAK-STAT signaling pathway
vlg04658
Th1 and Th2 cell differentiation
vlg04659
Th17 cell differentiation
vlg05145
Toxoplasmosis
vlg05160
Hepatitis C
vlg05161
Hepatitis B
vlg05162
Measles
vlg05164
Influenza A
vlg05165
Human papillomavirus infection
vlg05167
Kaposi sarcoma-associated herpesvirus infection
vlg05168
Herpes simplex virus 1 infection
vlg05169
Epstein-Barr virus infection
vlg05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
121495696 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
121495696 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
121495696 (TYK2)
04621 NOD-like receptor signaling pathway
121495696 (TYK2)
04658 Th1 and Th2 cell differentiation
121495696 (TYK2)
04659 Th17 cell differentiation
121495696 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
121495696 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
121495696 (TYK2)
05160 Hepatitis C
121495696 (TYK2)
05171 Coronavirus disease - COVID-19
121495696 (TYK2)
05164 Influenza A
121495696 (TYK2)
05162 Measles
121495696 (TYK2)
05168 Herpes simplex virus 1 infection
121495696 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
121495696 (TYK2)
05169 Epstein-Barr virus infection
121495696 (TYK2)
05165 Human papillomavirus infection
121495696 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
121495696 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vlg01001
]
121495696 (TYK2)
Enzymes [BR:
vlg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
121495696 (TYK2)
Protein kinases [BR:
vlg01001
]
Non-receptor tyrosine kinases
JAK family [OT]
121495696 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
RIO1
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
121495696
NCBI-ProteinID:
XP_041619474
LinkDB
All DBs
Position
7:complement(7407983..7430496)
Genome browser
AA seq
1180 aa
AA seq
DB search
MPLCHSGATTRDSRPDGDEAQPLATRGGLKVLLHWAGPGGGDPWVTFSEATLTAEDVCIH
IAHKVGITPSCFNLFALFDAEAQVWLPPNHILEVSGDMNLTLYFRMRFYFRNWHGTNSQE
PAVYRCGPTGTKSSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWDLSSEEEIHHF
KNESLGMAFLHLCHLALSHGIPLEKVAKKISFKDCIPRSFRLQIRRHNALTRLRLRSIFR
RFVRAFQPSHISQQVIMVKYLATLEQLAPRFGTERVPVCHLELLAQAVGKSCYIRDSGQA
PPEPELATRPPTHEVLVTGTGGIQWRPVQAESPRGNGSSKNRHADPFGKKTKAGEVGDQP
VDRPQEEPWVYFCDFQDITHVVLKERHISIHCQDNKSLELTLPSRAMALSWVSLVDGYFR
LTADSSHYLCHEVAPPRLVMSIQDGIHGPLMEPFVLAKLRSEDGLYLIHWSTSHLNRLIL
TVAQRDQSPGTQRLHLRKFPIELQAGVFRLEGWDRSFPSVRELRAALQGCSLRAGDDCFS
LRRCCLPRPGEISNLIIMRGPRAVTSSPNVSQLSFHRICQADVTQLSHLGQGTRTNVYEG
VLRVGTRAPMEGAADGEDSPTPSEDSGLELRVVLKVLDPSHHDIALAFYETASLMSQVSH
VHLAFVHGICVYGSENIMVTEYVEHGPLDVWLRREKGHVPVAWKVAVAQQLASALSYLED
KSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERIERIPWIAPECLTGG
ANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKECFYQKQHRLPQPSCPELATLISQ
CLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGEGH
FGKVSLYCYDPTNDGTGEMVAVKAIKAGCGPQLRTCWRREIDILRTLHHKHIVKYKGCCE
DQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYVHRDLAAR
NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSF
GVTLYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEKCPYEIYLL
MKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFNVC
NT seq
3543 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattcgggtgccaccaccagggacagcaggcctgatggcgatgaagct
cagcccctggccaccaggggaggcctgaaggtccttctgcactgggctggccctggtggc
ggggacccatgggtcaccttcagcgaggccacactgaccgcagaggatgtctgcatccac
attgcacacaaagtcggcatcactccgtcctgcttcaatctctttgctctcttcgatgcc
gaggcccaggtctggctgcctccaaaccacatcttggaggtctccggagacatgaatctg
accctgtacttccgcatgaggttttatttccggaactggcatggcacaaattctcaggag
ccggctgtgtaccgctgtgggcccacagggaccaagtcctcctcagaacaagcagagcag
ggggtgcagctactggacccagcctcctttgaatacctctttgagcagggcaagcatgag
tttgtgaatgacgtggcgtcactgtgggatctgtcgagcgaggaggagatccaccatttt
aagaacgagagtctgggcatggcctttctgcacctctgccaccttgctctctcccatggc
atccccctggagaaggtggccaagaagatcagcttcaaggactgcattccacgctccttc
cggctgcagatccggcggcacaacgcgttgacccggctgcgtctgcggagcatcttccgc
aggttcgtgcgggccttccagccgagccacatctcgcagcaggtcatcatggtcaaatac
ctggccacgctcgagcagctggcgccccgctttggcacggagcgcgtgcccgtgtgccac
ctggagctcctggcccaggccgtggggaagtcctgctacatccgggacagcgggcaggcc
cctccagagcctgagctggccaccagaccccccactcatgaggtgctggtgacaggcact
ggtggcatccagtggcggccggtacaggcagagagtcccagaggcaatggcagcagcaag
aatcgccatgctgacccatttgggaagaaaaccaaggccggagaggtgggtgaccagcca
gtggacaggcctcaggaagagccatgggtctacttctgtgacttccaggatatcacccac
gtggtgctcaaggaacgccacatcagcatccactgtcaggacaacaagagcctggagctg
accctgccttcccgggccatggccctgtcctgggtgtcgctggtggacggctacttccgc
ctgacagccgactcaagccactacctgtgccatgaggtggcccctccacggctagtgatg
agcatccaggacggtatccatggacccttgatggagccctttgtgctggccaagctgcgg
tctgaggatggcctctacctcatccactggagcaccagccacctcaaccgcctcatcctg
acggtggcccagcgggaccagagcccgggcacacagcgcttgcacctgcgtaaattcccc
attgagctgcaggccggggtcttcaggctggagggctgggaccggtccttccccagcgtg
cgggagctgcgagccgccctgcagggctgctccctgcgcgccggcgatgactgcttctcc
ctgcgccgctgttgcctgcctcggcctggagagatctccaacctcatcatcatgcggggg
ccccgggccgtcacaagttcacccaacgtcagccagctcagcttccaccggatctgccag
gctgatgtcacccagctgtcccacctgggccaaggcacgaggaccaatgtgtatgagggc
gtgttacgagtggggacaagagcccccatggagggcgcggcagacggtgaggactccccc
acacccagtgaggactctgggctggagctccgagtggtactcaaggtgctagaccctagt
caccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtctcccat
gtgcacctggcctttgtacatggcatctgcgtgtatggctctgagaacatcatggtgaca
gagtacgtggaacacgggcccctggacgtgtggctgcggcgagagaagggccacgtgccc
gtggcctggaaggtggcagtggcccaacagctggccagcgccctcagctacctggaagac
aagagcctggttcacggtaatgtgtgtggtcggaacatcctgctggcgcggctggggctg
gcggagggcaccagccccttcatcaagctgagtgaccccggtgtgggcttgggtgccctt
tccagagaggagcggatcgagcggatcccctggatagcccccgagtgcctgactggcggg
gccaacagcctaaccactgcggctgataaatggggctttggtgctaccctcctggagatc
tgcttcgacggggaggcccccctgcagggccgtggcccctccgagaaagagtgcttctac
cagaagcagcaccggcttcctcagccctcctgcccagagctggccacactcatcagccag
tgcctgacctacgaaccagctcagcggccctccttccgcaccatcctgcgtgacctcact
cagctgcagccccagaatcttgctgacgtcttggctgtgaaccccgactcacctgcatca
gaccccaccgtcttccacaagcgctatttgaaaaagatccgggatctgggcgagggccat
ttcggcaaggtcagtctgtattgctacgacccaaccaatgacggcactggtgagatggtg
gcggtgaaggccatcaaggccggctgcggcccccagctccgcacctgctggaggagggag
atagacatcctgcggacgctccatcacaagcacatcgtcaaatacaagggctgctgtgag
gaccaaggagagaagtcggtgcagctcgtcatggagtacgtgcccctgggaagcctacga
gactacctgccccggcacagcgtcggactggcccagctgcttctcttcgctcagcagatc
tgtgagggcatggcctaccttcacgcacagcactacgtgcatcgagacctggctgcccgc
aacgtgctgctggacaacgacagactggtcaaaatcggggactttggcctagccaaggct
gtgccggaaggccacgagtactaccgcgtgcgcgaagatggggacagccccgtgttctgg
tatgccccagagtgcctgaaagagtgtaaattctactatgcatccgacgtctggtccttc
ggggtcaccctgtacgagctactgacctactgtgactcgagccagagccccccctcgaaa
ttcatcgagctcataggcctcacccaggggcagatgacggtgctgaggctcacagagctg
ctggaacgaggggagaggctgccccggccagagaaatgtccttatgagatctatctcctc
atgaagaactgctgggaggcagaagcttcattccgccccaccttccagaacctcataccc
attctcaagacggtccaggagaaataccaaggccaggctgcctcagtgttcaatgtctgc
tga
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