Vulpes lagopus (Arctic fox): 121496246 Help Entry 121496246         CDS       T07435                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism vlg  Vulpes lagopus (Arctic fox) Pathway vlg04064   NF-kappa B signaling pathway vlg04066   HIF-1 signaling pathway vlg04145   Phagosome vlg04151   PI3K-Akt signaling pathway vlg04217   Necroptosis vlg04613   Neutrophil extracellular trap formation vlg04620   Toll-like receptor signaling pathway vlg04621   NOD-like receptor signaling pathway vlg04936   Alcoholic liver disease vlg05132   Salmonella infection vlg05133   Pertussis vlg05134   Legionellosis vlg05135   Yersinia infection vlg05140   Leishmaniasis vlg05142   Chagas disease vlg05144   Malaria vlg05145   Toxoplasmosis vlg05146   Amoebiasis vlg05152   Tuberculosis vlg05161   Hepatitis B vlg05162   Measles vlg05164   Influenza A vlg05170   Human immunodeficiency virus 1 infection vlg05171   Coronavirus disease - COVID-19 vlg05205   Proteoglycans in cancer vlg05235   PD-L1 expression and PD-1 checkpoint pathway in cancer vlg05321   Inflammatory bowel disease vlg05323   Rheumatoid arthritis vlg05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:vlg00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     121496246 (TLR4)    04066 HIF-1 signaling pathway     121496246 (TLR4)    04151 PI3K-Akt signaling pathway     121496246 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     121496246 (TLR4)   09143 Cell growth and death    04217 Necroptosis     121496246 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     121496246 (TLR4)    04620 Toll-like receptor signaling pathway     121496246 (TLR4)    04621 NOD-like receptor signaling pathway     121496246 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     121496246 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     121496246 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     121496246 (TLR4)    05161 Hepatitis B     121496246 (TLR4)    05171 Coronavirus disease - COVID-19     121496246 (TLR4)    05164 Influenza A     121496246 (TLR4)    05162 Measles     121496246 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     121496246 (TLR4)    05135 Yersinia infection     121496246 (TLR4)    05133 Pertussis     121496246 (TLR4)    05134 Legionellosis     121496246 (TLR4)    05152 Tuberculosis     121496246 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     121496246 (TLR4)    05144 Malaria     121496246 (TLR4)    05145 Toxoplasmosis     121496246 (TLR4)    05140 Leishmaniasis     121496246 (TLR4)    05142 Chagas disease     121496246 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     121496246 (TLR4)    05321 Inflammatory bowel disease     121496246 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     121496246 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     121496246 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:vlg04131]     121496246 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:vlg04054]     121496246 (TLR4)    04090 CD molecules [BR:vlg04090]     121496246 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:vlg00536]     121496246 (TLR4) Membrane trafficking [BR:vlg04131]  Endocytosis   Phagocytosis    Toll-like receptors     121496246 (TLR4) Pattern recognition receptors [BR:vlg04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    121496246 (TLR4) CD molecules [BR:vlg04090]  Proteins   121496246 (TLR4) Glycosaminoglycan binding proteins [BR:vlg00536]  Hyaluronan   Cell surface receptors    121496246 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR TIR_2 LRR_9 LRR_EndoS LRR_NXF1-5 LRR_Zer-1 ThsB_TIR Motif Other DBs NCBI-GeneID:  121496246 NCBI-ProteinID:  XP_041620559 LinkDB All DBs Position 7:complement(61396036..61408644) Genome browser AA seq 833 aa AA seqDB search MMSPTRLAGILIPAMAFLSCLRPESWDPCVQVVPNITYQCMELNLSKIPNNIPTSTKELD LSFNPLRHLGSHCFSNFPELQVLDLSRCEIQIIEDDAYQGLNHLSILILTGNPIQRLFPR AFSGLSSLKTLVAKETKLTSLEDFPIGHLKTLKELNVAHNLIHSFKLPAYFSNMPNLENV DFSNNKIQNIYRQDLQVLYKMPLLNLSLDLSLNPLYFIQPGSFKEIKLHELTLRSNFNST DVMKTFIQGLAGLKINQLVLGEFKNERKLESFDNSLLEGLCNLTIEKFRIAYFDSFSEDT TNLFNHLVNISAISLAHLYLDTPKYLPKNLRWQRLEIVHCNLEQFPAWELDSLKEFVLTS NKGINTFAEMKMESLEFLDLSRNGLSFKTCCSHSDFGTTRLKHLDLSFNEIITMSSNFLG LEQLEYLDLQHSSLKQTSDFSVFLSLRNLRYLDISYTRTEVVFHGIFDGLVSLQVLKMAD NSFPDNFLPNIFKGLTNLTILDLSGCHLERVSQVAFVSLPKLQLINMSHNSLLSLDTLAY EPLLSLRTLDCSFNRIVAFKEQGQQHFPSNLVSLNLTENKFACDCEHQSFLQWVKDHRQL LVEVEKMVCAKPLDMQDMPLLSFRNATCQRSKTIISVSVFTVLMVSLVAVLAYKFYFHLM LLAGCKRYNRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA ANIIQEGFYKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKSLL RQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPEGTEDAENS NT seq 2502 nt NT seq  +upstreamnt  +downstreamnt atgatgtctcctacccgcctggctgggatattgatcccagccatggccttcctctcctgc ctgagacctgagagctgggacccttgcgtgcaggtggttcctaacattacttaccaatgc atggagctgaatctcagcaaaatccccaacaacatccccacatcaaccaaggaactggac ctgagctttaaccccctgaggcatttaggcagccattgcttctccaacttcccagaactg caggtgctggatttatccaggtgtgaaattcagataattgaagatgatgcatatcagggc ctaaaccacctctccatcttgatattgacaggaaaccctatccagagattatttccaaga gccttttctggactatcaagtttaaagacgctggtggccaaggagacaaaactaacatct ctagaggatttccccattggacatctcaaaaccttgaaggagcttaatgtggctcacaat cttatccattccttcaagttacctgcatatttctctaacatgcccaacctggagaacgtg gatttttccaataacaagatccaaaatatttatcgtcaagacttgcaggttctatataaa atgccactactcaacctttctttagacttgtccctgaaccctttatactttatccaacca ggttcctttaaagaaattaaactccatgaactgactttgagaagtaattttaatagtaca gatgtaatgaaaacttttattcaaggtctggctggcttaaagatcaatcagttggttctg ggagaatttaaaaatgaaaggaagttggaaagctttgacaattctctcctggaaggactg tgcaatttgaccattgaaaaattccggatagcatactttgatagcttctcagaggatact actaatttatttaaccacttggtaaacatttctgcaatttctttggcgcatctgtattta gacacaccaaaataccttcctaaaaatctcagatggcaacggttggaaatagttcattgt aacttagaacaatttcccgcatgggagctggactctctcaaggagtttgttctcacttcc aacaaaggtattaacacttttgctgagatgaagatggaaagccttgagtttctagatctc agtagaaatggcctgagtttcaagacttgctgctctcactctgattttgggacaaccaga ctgaagcatttagatctgagcttcaatgaaatcattaccatgagttcaaacttcttgggc ttagaacaactcgaatatctagatttacagcattccagtttgaagcagaccagtgatttt tcagtattcttgtccctcaggaacctccgttaccttgatatttcttatactcgcactgaa gttgttttccatggcatttttgatggcttggtcagcctccaagtcttgaaaatggctgat aattcttttccggacaacttccttccaaatattttcaaagggctgactaacttaaccatt ctggacctttctgggtgtcatctggaacgggtgtcccaggtagcatttgtctcacttcct aaacttcagttgataaatatgagtcacaatagcctcttgtcattggatacactagcttat gaacctctcctctccctccggaccctagattgcagttttaatcgaatagtagccttcaag gaacaaggacaacagcattttccaagtaatctagtttccttaaatcttactgagaataaa tttgcttgtgattgtgaacatcagagtttcctgcagtgggtcaaagaccacaggcagctc ttggtggaagttgaaaaaatggtgtgtgcaaaacctttagacatgcaggacatgcccttg ctgagttttaggaatgccacctgtcagaggagcaagactatcattagtgtgtcagttttc actgtgctcatggtttctctggtagcagttttagcgtataagttctattttcacctaatg cttctcgctggctgcaaaaggtataacagaggtgaaagtacctatgatgcatttgttatc tactcaagccaggatgaagactgggtgaggaatgaattggtaaagaacttggaggaggga gtgcccccctttcagctctgccttcactacagagacttcattcctggtgtggccattgcc gccaacatcatccaggaaggcttctataagagccggaaggttattgttgtggtgtcccaa cacttcatccagagtcggtggtgcatctttgagtatgagattgcccagacttggcagttt cttagcagtcgtgctggcatcatcttcattgtcctgcagaaggtggagaagtccctgctg cggcagcaggtggagctgtatcgcctcctcagcaggaacacttacctggaatgggaagac agcgtcctggggcggcacatcttctggagacggctccgaaaagccttgctggatggtaaa ccgtggagtccagaaggaacagaggatgcagaaaacagctag

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