Vulpes lagopus (Arctic fox): 121499401 Help Entry 121499401         CDS       T07435                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism vlg  Vulpes lagopus (Arctic fox) Pathway vlg01521   EGFR tyrosine kinase inhibitor resistance vlg04151   PI3K-Akt signaling pathway vlg04217   Necroptosis vlg04380   Osteoclast differentiation vlg04550   Signaling pathways regulating pluripotency of stem cells vlg04620   Toll-like receptor signaling pathway vlg04621   NOD-like receptor signaling pathway vlg04630   JAK-STAT signaling pathway vlg04658   Th1 and Th2 cell differentiation vlg04659   Th17 cell differentiation vlg05140   Leishmaniasis vlg05145   Toxoplasmosis vlg05152   Tuberculosis vlg05160   Hepatitis C vlg05161   Hepatitis B vlg05162   Measles vlg05163   Human cytomegalovirus infection vlg05164   Influenza A vlg05165   Human papillomavirus infection vlg05166   Human T-cell leukemia virus 1 infection vlg05167   Kaposi sarcoma-associated herpesvirus infection vlg05168   Herpes simplex virus 1 infection vlg05169   Epstein-Barr virus infection vlg05171   Coronavirus disease - COVID-19 vlg05200   Pathways in cancer vlg05203   Viral carcinogenesis vlg05212   Pancreatic cancer vlg05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:vlg00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     121499401 (JAK1)    04151 PI3K-Akt signaling pathway     121499401 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     121499401 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     121499401 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     121499401 (JAK1)    04621 NOD-like receptor signaling pathway     121499401 (JAK1)    04658 Th1 and Th2 cell differentiation     121499401 (JAK1)    04659 Th17 cell differentiation     121499401 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     121499401 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121499401 (JAK1)    05203 Viral carcinogenesis     121499401 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     121499401 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     121499401 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121499401 (JAK1)    05161 Hepatitis B     121499401 (JAK1)    05160 Hepatitis C     121499401 (JAK1)    05171 Coronavirus disease - COVID-19     121499401 (JAK1)    05164 Influenza A     121499401 (JAK1)    05162 Measles     121499401 (JAK1)    05168 Herpes simplex virus 1 infection     121499401 (JAK1)    05163 Human cytomegalovirus infection     121499401 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     121499401 (JAK1)    05169 Epstein-Barr virus infection     121499401 (JAK1)    05165 Human papillomavirus infection     121499401 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     121499401 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     121499401 (JAK1)    05140 Leishmaniasis     121499401 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     121499401 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:vlg01001]     121499401 (JAK1) Enzymes [BR:vlg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      121499401 (JAK1) Protein kinases [BR:vlg01001]  Non-receptor tyrosine kinases   JAK family [OT]    121499401 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  121499401 NCBI-ProteinID:  XP_041625898 LinkDB All DBs Position 10:71692451..71818269 Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGLEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITIDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEMLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPHCPEEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaatctggaggcccctgaaccagggttggaagtgctcttc tatctttctgatagggagcccctccggctgggcagcggagagtacacagcagaggagcta tgcatcagggccgcgcaggaatgctgtatctctccactttgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccattgatgacaag acatcgctccggctccactaccggatgaggttctatttcaccaactggcacgggactaat gataatgagcagtctgtatggcgacattccccaaagaagcagaaaaatggctatgagaaa aaaaaagttccagatgctacccctcttcttgacgccagttctttggagtatctctttgct cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagactgagcag gatgggcacgatattgagaatgagtgtctgggaatggctgtcctggccatctcccactat gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctataagcgatat attccagagacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctgaaggaatttaataacaagactatttgtgacagtagt gtatctactcatgacctaaaggtgaaatatctggctaccttggaaactttgacaaagcat tatggtgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcatccgaacgacagtggaaacattctctactatgaagtgatggtaactggaaat cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa ctcaaacggaaaaaactggaaaataaacacaagaaggacgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttacttccctgaaatcacacacattgtaataaaggagtct gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcatcccatgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagatgcccat cattacctctgcactgatgtggctcccccattgatcgtccacaacatacagaatggttgt cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggaa gggatgtatgtgctgaggtggagctgtaccgacttcgacaatattctcatgactgtcacc tgctttgaaaaatctgagatgctgggtggccagaaacagttcaagaattttcagattgag gtgcagaagggccgctatagcctgcacggctcagaccgcagcttccccagcctaggggac ctgatgagccacctcaagaagcagatcctgcgtacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagcc caagagtggcagccagtctaccccatgagccagctgagttttgaccggatcctcaagaag gatattgtgcaaggcgagcaccttgggagaggcacacggacacacatctactctggtact ctggtggattataaggacgatgaaggaacctctgaagaaaagagaataaaagtcatcctc aaagtcttagaccccagccacagggacatttctctggctttctttgaggcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggaggggggacctctagatctcttcatgcaccgg aaaagtgatgtcctcaccacaccgtggaagttcaaagttgccaaacagctggccagtgcc ctgagttacttggaggataaagacctagttcatggaaatgtgtgcactaaaaaccttctc ctggcccgtgagggcattgacagcgagtgcggcccgttcatcaagctcagtgaccctggc atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctcct gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acattgtgggaaatctgctacaatggcgagatccctctgaaagacaagaccctgattgag aaagagagattctacgaaagccggtgccggccagtgacaccatcctgtaaggagctggct gatcttatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc atgagagacatcaataaactggaagagcagaatccagacattgtttccgaaagaaagccg gcaaccgaagtggatcccacacattttgaaaagcggttcttgaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggataatact ggggagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat ctgaagaaggaaatcgaaattctaaggaacctttatcatgagaacattgtgaagtacaaa ggcatctgtacagaagatggaggaaatggtattaagctcatcatggaatttctgccttca ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagtta aaatatgccgttcagatttgtaaggggatggactatttaggttctcggcaatatgttcac cgggacttagcagcaaggaatgtccttgttgagagtgaacaccaagtgaaaattggagac tttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaaggatgatcgg gacagccctgtgttttggtatgctcctgaatgtttaattcaatgtaaattttatatcgcc tctgatgtctggtcatttggagtgaccctgcatgagttgcttacttactgtgactcagat tccagccccatggcgttgtttctgaaaatgataggcccaactcatggccagatgacagta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctcactgtcca gaagaggtttatcaacttatgagaaaatgctgggaattccagccatctaatcggacaact tttcagaaccttattgaaggatttgaagcacttttaaaataa

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