Vulpes lagopus (Arctic fox): 121499483
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Entry
121499483 CDS
T07435
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
121499483 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
vlg01002
]
121499483 (BACE1)
Enzymes [BR:
vlg01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
121499483 (BACE1)
Peptidases and inhibitors [BR:
vlg01002
]
Aspartic peptidases
Family A1: pepsin family
121499483 (BACE1)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
121499483
NCBI-ProteinID:
XP_041626058
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All DBs
Position
10:42539526..42564136
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AA seq
501 aa
AA seq
DB search
MARALPWLLLWMGSGVLPARCTPPGIRLPLRSGLGAPPLGLRLPRETVEEPDEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFITLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccgagcactgccctggctcctgctgtggatgggctccggagtgctgcccgcccgc
tgcaccccgcccggcatccggctgcccctgcgcagcgggctgggggcgccccccctgggg
ctgcggctgccccgggagaccgtggaggagcccgacgagcccggccggaggggcagcttt
gtggagatggtggacaacctgagaggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctggtggacacaggcagcagtaactttgca
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagtaca
taccgggacctccgaaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccatggccccaacgtcactgtgcgtgccaacatc
gctgccatcaccgaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
ggtctggcctatgctgagatcgcaaggcccgatgactccctggagccattctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggcgctggcttc
cccctcaaccagtcagaagtgctggcctcggttggagggagcatgatcatcgggggtatc
gaccactcgctgtacacgggcagcctctggtacacacccatccggcgggagtggtactac
gaggtgatcattgtaagggtggagatcaacgggcaggacctgaaaatggactgcaaggag
tacaactatgacaagagcattgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgctgtcaaatccatcaaggcagcctcttcgacggagaagttcccagat
gggttctggctgggggagcagctggtgtgctggcaggcaggcaccaccccttggaacatt
ttcccggtcatctccctctacctgatgggcgaggtcaccaatcagtccttccgcattacc
atccttcctcagcaatacctgcggccagtggaagacgtggccacatcccaagacgactgc
tacaaattcgccatttcacagtcatccacgggcaccgtaatgggagctgttatcatggag
ggcttctacgttgtctttgaccgggcccgaaaacgaattggctttgccgtcagtgcttgt
catgtgcacgatgagttcaggacggcagcagtggaaggcccgtttatcaccctggacatg
gaagactgtggctacaacattccacagacagatgaatcaacgctcatgaccatagcctac
gtcatggctgccatttgcgccctcttcatgctgccgctctgcctcatggtgtgccagtgg
cgctgcctccgctgcctgcgccatcaacatgatgactttgccgatgacatctccctgctg
aagtga
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