Micromonospora maris: VAB18032_11245
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Entry
VAB18032_11245 CDS
T01471
Name
(GenBank) putative alpha-isopropylmalate/homocitrate synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
vma
Micromonospora maris
Pathway
vma00290
Valine, leucine and isoleucine biosynthesis
vma00620
Pyruvate metabolism
vma01100
Metabolic pathways
vma01110
Biosynthesis of secondary metabolites
vma01210
2-Oxocarboxylic acid metabolism
vma01230
Biosynthesis of amino acids
Module
vma_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
vma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
VAB18032_11245
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
VAB18032_11245
Enzymes [BR:
vma01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
VAB18032_11245
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AEB43367
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Position
1459091..1460668
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AA seq
525 aa
AA seq
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MTFQVYDTTLRDGAQREGVSYSVVDKLAVARLLDEFGVGFIEGGWPGAVPKDTEFFRRAR
TELELRHAVLVAFGATRRANTVAADDPQVRGLLDAQTPAIALVAKADLRHVERALRTTAK
ENLAMIHDTVTHLVAEGRRVFVDGEHFYDGYRHDPAYTASVVETALAAGAERFVLCDTNG
GMLPSQVTAAITDLTDRIGVAPELLGMHAQNDTACAVANTIAAVEAGVRHVQGTANGYGE
RPGNADIFAVVANLQLKLGLPVLPEGCLEQMVRVSHAIAEIANIAPDTHQAYAGAAAFAH
KAGLHASAIKVDPLLYNHVEPEVVGNDMRILVTEMAGRASIELKSRELGLDLAGHPEALS
RVTNRVKELEAGGWSFEAADASFELLVRSELPDAAPVRPFALESYRVLVEHREDGAVVSE
ATVKIRVRGERVIATAEGNGPVNALDEALRVGLGRHYPELRDFELADYKVRILEGSHGTG
AVTRVLVETANGRGGGWTTVGVHPNVVEASWHALVDALTYGLGRA
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgacgttccaggtctacgacacgaccctgcgcgacggtgcccagcgcgagggggtcagc
tactcggtggtcgacaagctcgccgtggcgcgactgctcgacgagttcggcgtcgggttc
atcgagggtggttggccgggcgcggtgcccaaggacaccgagttcttccgccgggcgcgc
accgagctggagctgcggcacgcggtgcttgtcgccttcggtgcgacccgccgggccaac
acggtcgccgccgacgatccccaggtgcgtggcctgctggacgcgcagaccccggcgatc
gcgctggtcgccaaggccgacctgcgacacgtcgagcgggcgctgcggaccaccgccaag
gagaacctggcgatgatccacgacacggtcacccacctggtcgccgagggccgtcgggtc
ttcgtcgacggggagcacttctacgacggctaccgccacgacccggcgtacacggcgtcg
gtggtggagaccgcccttgccgcgggcgccgagcggttcgtgctctgcgacaccaacggc
ggaatgctgccctcgcaggtcacggcggccatcaccgacctgaccgaccgcatcggggtg
gcccccgaactgctcggcatgcacgcccagaacgacaccgcgtgcgcggtggccaacacc
atcgccgccgtcgaggcgggcgtacgccacgtgcagggcaccgccaacgggtacggcgag
cggccgggcaacgccgacatcttcgcggtcgtcgcgaaccttcaactcaagctcgggctg
ccggtcctaccggagggctgcctggagcagatggtgcgggtctcccacgccatcgctgag
atcgccaacatcgcccccgacacccaccaggcgtacgccggggccgcagccttcgctcac
aaggcgggactgcacgcgagtgcgatcaaggtggatccgctgctctacaaccacgtcgaa
cccgaggtggtgggcaacgacatgcggatcctggtcaccgagatggccggccgggccagc
atcgagctcaagagtcgcgagctcgggctggatctggccggccatccggaggcgctgtcc
cgggtcaccaaccgggtcaaggagctggaggccggcggctggtcgttcgaggcggcggac
gcctcgttcgagctgctggtccgctccgaactgccggacgccgcgccggtacggccgttc
gcgctggagtcgtaccgggtgctggtcgagcaccgcgaggacggcgcggtggtctccgag
gcgacggtgaagatccgggtacgcggtgagcgggtgatcgccacggcggagggcaacggc
ccggtcaacgccctcgacgaggcgctgcgggtcggcctgggccgccactacccggagttg
cgggacttcgagctggccgactacaaggtgcgcatcctggagggcagccacggcaccggc
gcggtgacccgggtgcttgtcgagacggcgaacggccgtggcggcggctggaccacggta
ggcgtgcaccccaacgtggtcgaggcgagctggcacgcgcttgtcgacgccctcacctac
ggcctcggcagggcgtga
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