Virgibacillus necropolis: CFK40_12940
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Entry
CFK40_12940 CDS
T04976
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
vne
Virgibacillus necropolis
Pathway
vne00300
Lysine biosynthesis
vne00550
Peptidoglycan biosynthesis
vne01100
Metabolic pathways
vne01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
vne00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CFK40_12940
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CFK40_12940
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CFK40_12940
Enzymes [BR:
vne01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CFK40_12940
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
AAA_30
Motif
Other DBs
NCBI-ProteinID:
ASN05852
UniProt:
A0A221ME12
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Position
complement(2694294..2695652)
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AA seq
452 aa
AA seq
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MLFTTNWISTLFNNYKGVATDEIKINEIVTDSRMPSTKSLFIPIQGENFDGHDYIKEAFN
NGAIAAFWNKSKEVPSFLPTEFPLFYVEDTLEALQKLAAAYRSEINPVVIGITGSNGKTT
TKDLVASVMKTTYKTHATNGNFNNEIGLPLTILAMPRETEMLVLEMGMSNFGEIERLSKI
ALPDYAIITNIGESHIEYLGTRKGIAKAKTEIVKGMTDKGYLLIDGDEALLSELHNRNHV
ITCGFKAGNDVEIKNTIISHNHTEFNLADNSTFSIPLLGKHHALNATLAITLAKQLKIAD
HTIQQALSSLQLTSMRFEMIAGKNGVSIINDAYNASPTSMKAAIEVVKQMEGFSTKILIL
GDILELGEHSQTFHESVSEVIDGSISVLFTLGDQAKMISEKVNSKTEGTIVKHFTTKEEL
VDDLAFYLKEDTLLLFKASRGMQFEKMIEQIN
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgttatttacaaccaattggatttccactctttttaacaattataaaggtgtagcaact
gacgaaataaaaattaatgaaattgttacagacagcaggatgccttcaactaaatcactt
tttattccgattcagggtgaaaattttgatggccatgactatataaaagaagcatttaat
aatggagcaattgccgcattttggaataaaagtaaggaagtaccatcttttcttccaacc
gaatttcccttattttatgtagaggatacactagaagcactacaaaagttggctgcagct
tatcgaagtgaaataaatcccgtagttatcggaatcacaggatccaatggtaaaacaaca
acgaaagatcttgtagcttctgtgatgaaaacgacgtacaaaacacacgcaacaaacgga
aactttaataatgaaattggtctcccgcttacaattttggcaatgccaagagaaacagaa
atgttagtacttgaaatgggtatgagtaatttcggggaaattgaacgtttatcaaaaatt
gccttgccagattatgcaataataacgaatattggtgaatcacatattgagtatcttggc
acgcgtaaaggtatagcaaaggcaaaaacagaaatagtaaaagggatgacagataaagga
tacctacttattgatggtgatgaagcactattatcggaacttcataacaggaatcatgtt
ataacctgtggatttaaagcaggaaacgatgtagaaataaaaaatactattatttcacac
aatcataccgaatttaaccttgcagataacagcaccttttcaattccattattaggaaaa
catcatgctttaaatgctaccttagccattacacttgctaaacaattaaaaattgctgat
cacactattcaacaggcactatcatcgttacaattaacatctatgcgctttgaaatgata
gctggtaaaaatggtgtgtcgattataaatgacgcgtacaatgcatctccaacatcaatg
aaagcagcaatcgaagtagtcaaacaaatggagggcttttcaaccaagatcttaatctta
ggtgacatcttagagcttggggaacattcgcaaaccttccatgaatcggtaagcgaagta
atagatggatcaatttctgtgttgtttacattaggagatcaggcaaaaatgattagtgaa
aaggtgaattccaagacagaaggtacgatagttaaacattttactacaaaagaagaactt
gttgatgacttggcgttttacttaaaagaagatacactactattatttaaagcttcacga
ggtatgcagtttgaaaaaatgattgaacaaattaactaa
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