Vibrio nigripulchritudo: VIBNI_A0288
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Entry
VIBNI_A0288 CDS
T02871
Symbol
thrA
Name
(GenBank) fused aspartokinase I; homoserine dehydrogenase IBifunctional aspartokinase/homoserine dehydrogenase 1 [Includes: Aspartokinase; Homoserine dehydrogenase]
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vni
Vibrio nigripulchritudo
Pathway
vni00260
Glycine, serine and threonine metabolism
vni00261
Monobactam biosynthesis
vni00270
Cysteine and methionine metabolism
vni00300
Lysine biosynthesis
vni01100
Metabolic pathways
vni01110
Biosynthesis of secondary metabolites
vni01120
Microbial metabolism in diverse environments
vni01230
Biosynthesis of amino acids
Module
vni_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vni_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vni_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vni00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
VIBNI_A0288 (thrA)
00270 Cysteine and methionine metabolism
VIBNI_A0288 (thrA)
00300 Lysine biosynthesis
VIBNI_A0288 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
VIBNI_A0288 (thrA)
Enzymes [BR:
vni01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
VIBNI_A0288 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
VIBNI_A0288 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CCO56491
UniProt:
U4K1S0
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All DBs
Position
1:311319..313778
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADADRFLRAADIIANNAKQEQVAVVLSAPGKTTNKLVSVIEGALRNGEA
DLQIAELESSLQSLFDEVQKQVPNLESAGFNNQLKTSLSQLRQFVHGINLLGMCPNNVNA
RIISKGERISIQLMKAVLEAKGHPSFLIDPVEYLVAKGDHLEAMVDVDVSTNNFRANPLP
EDHVYIMPGFTAGNEKGELVTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV
DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDNLAIKGITTLNKLTMVNVSGPGMKGMVGMASRVFGAMSSAGVSIVLITQSSSEYSISF
CIEQADKAKAEQVLSDAFELELKDGLLEPVEFMNDVAIVTLVGDGMRTSRGVASRFFASL
AEVNVNVVAIAQGSSERAISAVIPEDKVSEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIQRQQAKLADKGIVIRVCGLANSKGLLLDSKGLPLDHWRDRMTHASEEFSLASLIAL
VQRNHIINPVLVDCTSSENIANQYADFLAAGFHVVTPNKKANTASMAYYHQLRDVARASR
RKLMYETTVGAGLPVIENLQNLISAGDELEKFNGILSGSLSYIFGKLDEGMTLSQATNIA
KDNGFTEPDPRDDLSGMDVARKLLILARESGLELELDDVVVEAALPPGFDDSGSVEEFMA
RLPEADAHFSKLSKKAAEEGKVLRYVGEILDGKCKVSIAAVDENDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTEVTAAGVFADVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttttaaagtttggtggatcgtcgttggcagatgctgatcgctttttaagagcg
gcagacatcattgctaataacgcgaagcaagagcaggtggcagtggtgctgtctgcccca
ggaaaaaccaccaacaaattggtgtcagttattgaaggtgcactcagaaatggcgaagcg
gatctacaaatcgcggagctggagtcttctcttcaatcgctgtttgacgaagtacagaag
caagtgccaaatttggaaagcgcgggtttcaacaatcagttgaagacctctctgagtcag
cttcgtcagtttgtacatggcatcaatcttttgggtatgtgcccaaataatgttaatgcc
cgcatcatcagtaaaggtgagcgcatttccattcagctaatgaaagctgttctggaagca
aaaggtcatccttctttcctgatagaccctgttgaataccttgttgctaaaggcgaccac
cttgaagctatggtcgatgttgatgtctcaaccaataacttccgtgctaaccctcttcct
gaagatcatgtttacatcatgcctggcttcaccgctggaaatgagaaaggtgaactggta
acccttggtcgtaacggctccgattactctgctgcagttctggcagcgtgcttacgcgca
gaatgttgtgaaatctggactgacgtagacggcgtatacaactgtgaccctcgtctggtt
gacgatgcaagactgcttaagtctctgagctaccaagaagcgatggagttgtcttacttc
ggcgcttccgttcttcacccaaaaaccattgcacctatcgcgcagttccatattccgtgt
ctgatcaaaaacagctttaatccgcaaggtgcgggtacattgattggtcaggacacaggc
gaagacaacctggcgatcaaaggcatcacgaccctgaacaaactgaccatggtaaacgtg
tctggtcctggcatgaaaggcatggttggcatggcgagccgcgtgtttggcgcgatgtca
tctgcaggcgtttctattgttctaatcacccagtcttcttctgagtacagcatcagtttc
tgtatcgaacaggcggataaagctaaagctgaacaggtacttagcgatgcattcgaactt
gagctcaaagatggcttgttagaacccgttgagtttatgaatgatgtagccatcgtcact
ctggttggtgatggtatgcgtacctctcgcggtgttgcgtctcgcttcttcgcatcatta
gctgaagtgaacgttaacgtagtggctatcgcacagggttcttctgaacgtgccatttct
gcggtgattccagaagacaaagtgtctgaagccatcaaagcgtgtcacgaaaacctcttt
aactctaagcacttccttgatgtatttgtggtcggtgttggtggagtcggtggtgagctg
gtggatcagatccagcgtcagcaagcaaaactggcagacaaaggcatcgtaatacgagta
tgtgggttagcaaacagcaaaggcttgctgctagatagcaaaggtctgccgcttgaccac
tggcgtgatcgaatgactcacgcgtcggaagagttcagccttgccagtctgattgcactc
gtacagcgtaaccacatcatcaacccggttctggtggattgtacgtctagcgaaaacatc
gctaatcaatatgccgacttccttgcggcaggtttccacgttgttacgccaaacaaaaag
gccaacacagcaagcatggcgtactaccaccaacttcgcgatgtggcgcgcgcgtctcgc
cgcaagttgatgtacgaaacaacggtaggtgcaggtcttccggttatcgagaacttacaa
aacctaatctctgcgggtgatgagctagagaaattcaacggtattctttctggttcactg
tcttacatcttcggcaaattggacgaaggcatgactttgagtcaggcaactaacattgca
aaagacaacggttttactgagccagacccacgtgacgacctttcgggtatggacgtggca
cgtaaactactgatccttgctcgtgaatctggtttagaacttgagctggacgacgtcgtt
gtagaagcggctctgcctccgggttttgatgacagcggaagtgtggaagagtttatggct
cgcctgccagaagcggatgcgcatttcagtaagttgtctaagaaagcggcagaagaaggg
aaagtgcttcgctatgtcggtgaaattctggacggcaagtgcaaagtgagcattgcggca
gtggatgaaaacgacccaatgttcaagattaaagatggcgaaaatgccctggcattctac
agccgttactatcagccaattccattggtgctgcgcggatacggcgcgggtacagaagtg
actgcggcaggtgtcttcgcagatgtgatgcgtacgttaggctggaaattaggagtataa
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