Vibrio navarrensis: IF132_12750
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Entry
IF132_12750 CDS
T07785
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vnv
Vibrio navarrensis
Pathway
vnv00260
Glycine, serine and threonine metabolism
vnv00261
Monobactam biosynthesis
vnv00270
Cysteine and methionine metabolism
vnv00300
Lysine biosynthesis
vnv01100
Metabolic pathways
vnv01110
Biosynthesis of secondary metabolites
vnv01120
Microbial metabolism in diverse environments
vnv01230
Biosynthesis of amino acids
Module
vnv_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vnv_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vnv_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vnv00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
IF132_12750 (thrA)
00270 Cysteine and methionine metabolism
IF132_12750 (thrA)
00300 Lysine biosynthesis
IF132_12750 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
IF132_12750 (thrA)
Enzymes [BR:
vnv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
IF132_12750 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
IF132_12750 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QOD69637
LinkDB
All DBs
Position
1:complement(1299996..1302455)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADAERFLRAADIIANNAKQEEVSVVLSAPGKTTNKLVAIIESALKHGEA
ERQIAEVEESFHQLFDDIKQQVPDIDGGDYLGQVASSLSQLRQFVHGIGLLGMCPDNVNA
RIISKGERVSIQLMKAVLAAKGHAVNLIDPVEYLLAKGDHLEGMVDVDISTQNFRNKPLP
AGHVHIMPGFTAGNKQGELVTLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
EDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDKLAIKGITTLNNLTMVNVSGPGMKGMVGMASRVFGAMSASGVSIVLITQSSSEYSISF
CIEAADKATAAQALADEFELELKDGLLEPVEFLSDVAIITLVGDGMRTSKGVASQFFASL
AEVNVNIIAIAQGSSERAISAVIPEDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIHRQQAKLADKGIVIRVCGLANSKGLLLDSNGLPLDHWRDRIKNATEEFSLPRLIAT
VQRNHIINPVLVDCTSSEAIANQYTEFLAAGFHVVTPNKKANTASMAYYHQLRDVARSSR
RKLMYETTVGAGLPVIENLQNLIAAGDELERFTGILSGSLSFIFGKLDEGMSLSEATNIA
KQNGFTEPDPRDDLSGMDVARKLLILAREAGMSLELEDVEVDQALPPGFDDSGSVEEFMA
RLPEADAYFKQQLAQAAQEGKVLRYVGEIIDGKCKVSIAAVDENDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTQVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattgaagtttggcggctcatcgttagccgatgctgagcgcttcttaagggcg
gcagatatcattgccaataatgcaaaacaggaagaggtttccgttgttttatcagcaccg
ggaaaaacaaccaacaaattagtcgctatcatagagtcggcgttaaaacacggtgaagcg
gaacggcaaatcgcagaggtagaagaatcattccaccaactgtttgatgacattaaacaa
caagtccctgacatcgatggtggagactacctcggccaagtggccagttcgctttctcag
ctacgtcagtttgtgcatggcatcggcctgttggggatgtgtcctgacaacgtgaacgcc
cgcattattagtaaaggtgagcgcgtatctattcaattgatgaaggcggttcttgctgct
aaaggtcatgcggttaacttaattgacccggtcgaatatctgttggctaaaggcgaccat
ctcgaagggatggtcgatgttgacatttccacgcaaaacttccgtaacaagccgctacct
gcaggccacgtgcacatcatgccggggtttaccgcgggtaacaaacaaggtgagttggtc
acgcttggacgtaacggttctgactactcggcggcggtgcttgcggcatgtttgcgcgcg
gattgctgtgaaatctggacggatgttgatggcgtttacaactgcgatccacgattggtt
gaagatgctcggctactcaaatcgctcagctatcaagaagcgatggagctctcttacttt
ggcgcttctgtgctgcatccgaagaccattgcgcctatcgcgcagtttcatattccttgc
ttgatcaaaaatagcttcaatcctcaaggggcaggtacgctcatcggccaagatactggc
gaagataaactggcgattaaaggcattaccacgctcaacaatttgaccatggttaacgtt
tccggtcctggcatgaaaggcatggtcggcatggccagccgagtgtttggtgcgatgtct
gcttccggtgtatcgattgtcctgattactcaatcttcttctgaatacagcatcagtttt
tgtatcgaagcggcagataaagccactgccgctcaagccctcgccgatgaatttgagctc
gagttaaaagatggcttgcttgagcctgtcgagtttctcagcgacgtcgccattattacc
ttggtgggcgatggcatgcgcacttccaaaggcgtagcatcgcaattttttgcctcgctg
gcggaagtgaacgtgaacatcattgcgattgcgcaaggctcctctgaacgcgcgatttct
gcggtgattccggaagataagatttccgaggcgattaaagcgtgccacgagaatctgttt
aattccaaacacttcttagatgtgttcgtggttggtgtcggcggtgtcggtggcgaactg
gtcgatcaaattcatcgccagcaggcaaaactcgctgataaagggatcgtgattcgtgtc
tgtggtctcgccaacagtaaaggcctgctgttagacagtaatggcttgccactggatcac
tggcgcgatcgcatcaaaaatgcgaccgaagagtttagcctgccgcgtttgatcgctacc
gtgcagcgcaaccatattattaatcctgtgctggtggactgtacttccagtgaagccatc
gcgaaccaatataccgagtttctcgctgcgggcttccatgtggtcacgccgaataaaaag
gctaacacagcgagcatggcgtattatcaccaattgcgcgatgtcgcgcgtagctcgcgc
cgcaagttgatgtatgagacaaccgttggtgcaggccttccggtgattgaaaacttacaa
aacctgattgccgcgggggatgagctggagcgttttaccgggatcctgtcaggctcactc
tcatttatcttcggcaaattggacgaagggatgagcttaagtgaagcgaccaacattgcg
aaacaaaacggcttcactgaacccgatccgcgtgatgatctctcgggcatggatgtcgcg
cgcaagctattgatcctcgctcgtgaagcgggtatgtcactggagctggaagatgtagaa
gtggatcaagcattgccaccgggtttcgatgattccggcagtgttgaagagtttatggct
cgcttacctgaagcggatgcctactttaagcagcaactcgcgcaagctgcgcaagaaggg
aaggtgttgcgttacgttggcgaaatcatcgatggcaaatgcaaagtgtctatcgcggcg
gtggacgaaaacgatcctatgttcaagatcaaagatggcgagaacgcactggctttctac
agccgctactatcaaccaattccattagtcttacgtggttacggcgcgggtactcaggtg
actgcggcgggcgtgttctcggacgtaatgcgtacactcggctggaaattaggggtttaa
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