Candidatus Vesicomyidisocius calyptogenae: COSY_0159
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Entry
COSY_0159 CDS
T00530
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
vok
Candidatus Vesicomyidisocius calyptogenae
Pathway
vok00300
Lysine biosynthesis
vok00550
Peptidoglycan biosynthesis
vok01100
Metabolic pathways
vok01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
vok00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
COSY_0159 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
COSY_0159 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
COSY_0159 (murF)
Enzymes [BR:
vok01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
COSY_0159 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAF61290
UniProt:
A5CXN1
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All DBs
Position
complement(169282..170562)
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AA seq
426 aa
AA seq
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MLQTTTNTIAKVLKIDYSVNVKFKGVYTDTRKRMDGALFIALVGDNFDAHDYIYQAQQMG
AVAIIANKSVDSQLPILVVNDTQTALSTIASWHLQNIKPIVIAITGSNGKTTTKNMLANI
LSLQAPTLKTQGNLNNHLGVPMTLLTLEKQHQYAVIEMGANHLGEISHLRKIVNPDIAIV
TNTLDAHIGTFGGFDNLVKAKGEIYSKNSKNIINTQSIFTGDVSFTPHGNTKVSGNNGDI
FASNIVNNKFDLNIHQQKISITLNLIGIHNIDNALAASACVYPLGIDINLIKQGLEATKA
EPGRLEIIHTKQFRIIDDTYNANPYSTIIALKTLQNFSGEKIIVLGTMEELGNYSKMFHF
KIGQLAKKSADTFYSYGKIALHHCSIHFEKKQPLANHILTNHTNATILIKGSRMAKLNKL
VDLLKK
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgctacaaactactacaaatactattgctaaagtattaaaaatagattactctgttaat
gttaaatttaaaggcgtttatactgatactcgaaaacgcatggatggagcgttatttata
gctttggttggcgacaactttgatgcacatgactatatctatcaagcacaacaaatgggt
gcagtagcaatcattgctaataaatctgtagatagtcagttaccaatattagtagtgaat
gatacacaaactgcacttagtacaattgctagttggcacctccaaaatatcaaacctatt
gttatcgctattacaggtagtaatggtaaaactactaccaaaaatatgctagctaatatt
ctaagtttacaagccccaacattaaaaactcaaggtaatctaaataaccacttaggtgtt
ccaatgactttattaacattggaaaaacaacaccaatatgcagtgatcgaaatgggagct
aaccatttaggtgaaatttcacatcttcgtaaaatagttaatcctgatattgctattgta
actaatacacttgatgcacacattggtacattcggtggatttgataatttagtcaaagcc
aagggtgaaatttattcgaaaaactctaaaaatattattaatactcaaagcatttttaca
ggtgatgttagttttaccccccatgggaatactaaagtaagtggtaataatggtgatatt
tttgctagtaatattgttaataacaagtttgatttaaacattcatcagcaaaaaatatca
atcacacttaacttgattggtatacacaatattgataatgccctagcagctagtgcctgt
gtatatccattaggaattgatatcaacctaatcaagcaaggtttagaagcaacaaaagca
gaacctggtaggttagaaattatccatactaaacaatttagaattattgacgatacttac
aacgccaatccatactcaactattatcgctcttaaaactttacagaatttttctggagaa
aaaattattgtactcggtactatggaagaattaggcaattattcaaaaatgttccatttt
aaaattggacaattagccaaaaaatctgctgatactttttatagctatggaaaaatagca
ctacaccactgtagtatccacttcgaaaaaaaacaaccattagctaaccatatactgact
aaccatactaacgctactatattaataaaaggctctagaatggcaaaactaaataagttg
gttgatttactaaaaaaataa
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