Vicugna pacos (alpaca): 102525512
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Entry
102525512 CDS
T08098
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X2
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102525512 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
vpc03021
]
102525512 (SETX)
Enzymes [BR:
vpc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
102525512 (SETX)
5.6.2.5 RNA 5'-3' helicase
102525512 (SETX)
Transcription machinery [BR:
vpc03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
102525512 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
Viral_helicase1
AAA_16
SLFN-g3_helicase
ResIII
Helicase_RecD
UvrD_C_2
CxC6
Motif
Other DBs
NCBI-GeneID:
102525512
NCBI-ProteinID:
XP_015105313
UniProt:
A0A6J0B097
LinkDB
All DBs
Position
4
AA seq
2601 aa
AA seq
DB search
MSTCCWCTPGGVSTIDFLQRYASRIHSSEFQTANEDLCYCLECVAEYHKARDELPHLHEI
LWELETLRLINHFEKSMTAEMGDDDVYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKYP
YLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGKV
DRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLGI
CMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRLG
SKVWGQLIDPIEAFQTIINNTSYNKEIQNIRNSSVRAKLEPESYFDDMVTCSQIVYNYNP
EKAKKDSGWRSAICTDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMDL
KDLGVAYIVEVIHHLHSEVKDVLNQPDAMCDKVTEFFLLILISVIELHRNKKCLHLLWVS
SQQWVEAVVKCAKLPTSAFARSSEKSSGNCSKGMGMISSLSLHSMPSNSVQLACVQLIRS
LLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQACLKQIIRNIKFKVPQ
SSAFMDLSPLCKTPLVSCKEESELLGKKSKKDMNSPTFSKQPMKAETHQLQASILSKANN
EQNHIKDLKLDHLSAEPCLKQRSKNITERAQDQMKVSTGKCKSVKENASCTPQNCTSRNG
PERVFDRGIIMLTDSSTDSLEKVSTSNEDFSLKDDALGKTSKTKTKTQKDEICAKLSHVI
KKPHRKSSVVSSAVSLEENLPVSSIESFYSRKDLGQKGDGFMHNLSLDANGILDEKNGEQ
KSNSLLLKKKQIKKEELDTPENSCQIQECHVGDKNLFAEMPNTIVKKTPFKDPVTVLETR
GKDISKCTDQVSSALRELPPSISPKSDILTDSQIDRDLHNLSLIAQASVTKFPSDLTQTS
SSQLQRKVKDDKRCFTANQNNGKTCRGHVIIISDSDDDDDDDERILGFEKLIKQDELCIG
KACPEQHTSVADMNVKQKVIKEEKTKSLLEFEESDSQFFEFESPFEMFSVWQDQKPDNNS
SFQEGEKNSCLTHIGDTTNDWGYDTDCVSGEVIKKVAEGVEEQAEPQRRSISVEEFCEIE
VKKTKRKRYEKPMAEDHLRPSSVRSKDHSDLNERELTEDDVKSADVRTTAPSSSIQRPTA
ASLKKSPPKLRTCSKPVRKVSLSKTPKKTHSDTKKGQNKSSSYISCRTTPAVVPPKKFRQ
CPEPTSTVEKLGLKKAPRRAFELSQRSLDSISRLRDYGKTVGVVDTRKKAKLISPQTLSV
RNNKKLLTSQDLQLRRQMRPKLQQNRQRLLDCESTVTPRAGPHAAQDSDTFVPESDRSDY
SHKGVSEVAANNNEKQLKCVSSETEPTKAKDVSEVTDDPCLLNWCSSVVWNGRIPTSEVI
VSTSEDPLGGGDLTVHHLEVASLKEGEPESSSDIEGDDIFLTQRDPEDMDLCSQMEKEND
NLIEVVHGKDTVQVEEVSTSRPQLESVSSTKCKYKDCVETLKNQGEYCSKHSEAKAADED
VFRKPGLPLSVSKPSRPSTTKIFSSSSTSRIANLSKSLENTSALPPALKKSTGIQSVLKV
PQPTSLVSQKPMGEVKSTCNILHPQTPNNSSRQGYKVPLGESKSFPVSSPVNILSSQSVS
DTFVKEVLKWKYDMFMNFDQYGPPSSLCQSIARHVPVRFQDCGDYFNVFFPLMILNTFET
VAQEWISSPNKEKFHQLQLRKFPADYKKYWEFVVYLEECELAKQLHPKENDLVFLVPERL
NEEKKDLQRNFVLDPHEYHCGYVHKFRRTSVMRNGKSECSVSIQTQDNLPVSLSEFVKCI
VISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERIIAYLRDFNEDQ
KKAIETAYAMVRHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTERRGHSDENSNAKIKQ
NRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFS
LDSQVNHRMKKELPSHVQEMHRRKEYLDRQLDELSRRRALCRGGREVQRQELDEKIAEVS
KERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIV
DEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEEN
VEHNMVGRLPVLQLTVQYRMHPDICLFPSNYVYNRNLKTNRLTETNRCSSDWPFQPYLVF
DVGDGSERRDNEPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQRLNVTITRA
KYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDKNYRHDAMKILKLKPMLQRSLTH
PPAVSPEASRPQGGLPSSKLDSEFAKTSFTSSVYLSPSDSKEATVTAKDPERPSIQDRLR
DPRLLRRFGLIPEAKEQCLWEPQPPSPQPPGAAPPSGEPGSPGSHQGPAGTGQQSAAKGA
APSNHRPHAQCDPPAASADAPTSKRKCDQEEGLSHRRETRAFSEGDQERCGSGSHHPKRN
SGLDERGLEKEDSSLKRRRLL
NT seq
7806 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcctggtggtgtttccaccattgacttcctacagcgc
tatgcatccaggatccactccagtgaatttcagacagccaacgaagacctctgctactgc
ttagagtgtgtggctgaatatcacaaagcaagggacgaattgccacacttacatgagatt
ttatgggaattagaaaccttacgtctcataaaccactttgaaaaatccatgacggcagaa
atgggagacgacgacgtgtacatagtagacaacaatggggaggcacagctgttcgacttc
actggccaagacttcgaaaataagctgcgagttcctcttctcgaaatactgaagtatcct
tatctgcttttacatgagcgtgttaatgaattatgtgttgaagcactttgccgaatggaa
caagctaattgctcctttcaggtttttgacaaacatccagggatctatttgtttttggtc
catcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttggggaaagtg
gacagagatgattattatgacttacaggaggttttgacttgcctttttaaagtcattgag
ttggggcttttagaaagtccagatatttatacttcttctgtccttgagaagggtaaactg
attcttctgccctcacacatgtatgatactaccaactacaaaaactattggttaggtatt
tgcatgttgctgaccattctcgaggagcaagccatggattcactgttgttggggtcagac
aaacaaaatgattttatgcagtcaatacttcacaccatggaaaggcaatcagatgatgat
agtgtggatcctttctggccagctttacactgtttcatggtgattctggatcgccttgga
tctaaggtctggggtcaacttattgatcctatagaggcatttcaaaccattatcaacaat
acaagctacaataaagagatccaaaatatacggaacagctctgtgagggccaagttagaa
ccagagtcgtattttgatgatatggtgacttgcagccagattgtgtacaattataatcct
gaaaaggccaaaaaggattcaggatggagatcagccatttgcacagattattgtcctaac
atgtatgaagaaatggaaacattagccagtgtgcttcagtcagatattggtcaagacatg
cgtgttcataacagcacatttctgtggttcatcccttttgttcagtccctcatggatctg
aaggatttgggtgtggcttacatagtggaggttattcatcatctgcattctgaagtcaaa
gatgtcctcaaccaaccagatgccatgtgtgacaaagtcactgagttttttcttctgatt
ttgatatcagtgattgaacttcataggaataaaaaatgtttgcatttgctgtgggttagt
tcccagcagtgggtggaagccgttgtaaagtgtgccaagcttcccaccagtgcgtttgca
cggagttctgagaagtcatcgggaaattgctccaaaggaatgggaatgatatcgtctctg
tcattgcattcaatgccatctaactctgtgcagctggcttgtgtgcagctgattagaagt
ctccttaaagagggttatcagcttgggcagcaaactctgtgtaagcgattctgggataag
ctcaacttattcctgcgaggaaatttatctttaggttggcagttgaccagtcaggaaacc
catgagttacaggcttgtttaaagcaaattatcagaaacataaaattcaaagtacctcag
agtagcgctttcatggatctgagtcctctgtgtaaaacccctcttgtatcttgtaaagaa
gaaagtgaactgttagggaagaaatctaaaaaggacatgaacagcccaacattttctaaa
caaccaatgaaagctgagacacatcaactgcaagcaagtattttgagcaaagcaaataat
gagcaaaaccacataaaagatctgaaactagaccacctctcagctgagccttgtttaaag
cagagaagtaaaaacatcactgaaagagctcaagaccaaatgaaagtaagtacagggaag
tgtaagtctgtaaaagagaatgcctcatgtacaccgcagaattgtacttcaagaaatggt
ccagaaagggtatttgacagaggaataataatgttgactgattctagcactgattctctg
gaaaaggtgtccacatcaaatgaggatttctctttaaaggatgatgctctgggcaaaacc
tcaaaaacaaaaactaagacacagaaagatgaaatctgtgctaagttatcacatgtaata
aaaaagccacaccggaaaagttccgtggtcagcagtgctgtcagtttagaggaaaacctg
cctgtatctagcattgagagtttctattcaaggaaagatctaggtcagaaaggagatggc
ttcatgcataacctctctttggacgctaatggtattctggacgagaaaaatggagaacaa
aagtcaaacagtttattgctgaaaaagaaacaaataaagaaggaagagttggatacccct
gaaaacagctgtcaaatacaggagtgtcatgttggtgataagaatttgtttgcagaaatg
cccaatactattgtgaagaaaacaccttttaaagatcctgtgactgtacttgaaacaaga
ggtaaggatattagcaagtgtaccgaccaggtttcttctgctttgagagaactgccccct
agcatcagtcctaagtctgacatcttaacagattctcagatagacagagacctccacaac
ttatctctaatagctcaagccagtgttactaagttcccatcagatttgacccaaacaagt
tcatcccagctacaaagaaaagtaaaagatgataaaagatgtttcacagctaaccaaaat
aatgggaaaacctgccgtgggcatgttattattatctcagattctgatgatgatgatgat
gatgatgaaagaattctgggttttgagaaactcattaaacaggatgaactgtgcattggg
aaggcctgtccagagcagcatacttcagtagctgatatgaatgtgaaacagaaggtgatc
aaggaagaaaagacaaagtccctgttggagtttgaggaatctgattctcagttttttgag
tttgaaagtccatttgaaatgttttcagtttggcaagatcagaaaccagacaacaacagt
tcatttcaagagggtgaaaaaaattcatgcttgactcatataggtgataccacaaatgac
tggggttatgatacagattgtgtgtctggagaggtcattaaaaaagtagcagagggtgtc
gaggaacaagcagaaccacagaggaggagtatttctgttgaagagttttgtgaaattgag
gtaaaaaaaaccaagagaaaacgatatgaaaagcctatggctgaagatcatctaaggcct
tcttctgtcagaagtaaggaccactctgatcttaacgagagagagctaactgaagatgat
gtaaaaagtgcagatgtaaggaccacagctcccagttcaagtattcagagacccaccgcg
gcgtccctaaagaagtcccctccaaagcttcgcacttgctccaaacctgttcggaaagtc
tcactttctaaaactcctaagaagacacattcagataccaaaaaagggcagaataaaagt
tcaagttacataagctgtcgaacaactcccgctgttgtgccaccaaagaaatttcgccag
tgtccagaaccaacttcaacggttgagaaacttggtctgaaaaaggctcctcgtagggca
tttgagttgtctcagcgatctttagactctatatctcggttacgtgactatggcaaaact
gttggagtagtcgatacccggaaaaaggctaaattaatttctcctcaaactctgtctgtc
agaaataataagaaattgctgacgagtcaagaccttcagttgcgaaggcagatgagaccc
aaattgcaacaaaataggcaaagactccttgactgtgaaagtacagttactccaagagca
gggccgcacgcagcacaggattctgacacatttgtaccggagtccgataggtcagattat
agtcataaaggggtatctgaggtagctgctaacaataatgaaaaacagttaaaatgtgtg
tcttctgaaacagaacccacgaaagcaaaagacgtttctgaggtaactgatgatccttgt
ctcttgaactggtgcagttctgtagtgtggaatggaagaataccaacgagtgaagtcatt
gtctctacttcagaggaccctttaggtggaggtgacctaacagtacatcatttagaggtg
gcatctttgaaagagggagagcctgaatccagcagcgatatagagggagatgatatattt
ctaacacagcgtgatcctgaagatatggatttatgttcacaaatggagaaagagaatgat
aacctcattgaagtagttcatggaaaagacacagttcaggtagaagaagtttccaccagt
cggcctcagttggaatctgtgagtagcacaaaatgtaagtataaagattgtgttgaaact
ctgaaaaaccagggtgaatactgctcaaaacactcagaagctaaagcagcagatgaagat
gtatttcgtaaacctggcttgcctctctctgtgtctaaaccttccagaccctccactact
aagatttttagctcaagtagtacttcgcgaattgctaatctttccaagtctttggagaat
acctcagcacttccaccagctctaaaaaagtcaactgggatacagtctgttttgaaagta
ccacagccgacttctctggtgtctcagaagccaatgggtgaagtgaagagtacatgcaac
atccttcatcctcagactccaaataattccagcaggcaaggttacaaagttccacttggt
gaaagcaaatcttttccggtctcctctccagtaaacatcttgtcatcacagtccgtctct
gacaccttcgttaaagaggtcttaaaatggaagtacgacatgttcatgaactttgatcag
tatgggcccccgtcaagtctttgtcagtccatcgcaagacacgtgcctgtcagattccaa
gactgtggagattattttaatgtttttttccctttgatgatattgaatacttttgaaaca
gtggcacaggaatggatcagctctcccaataaagagaaattccatcagttgcaattacga
aaatttcctgctgattataaaaaatactgggagtttgtggtttatcttgaggaatgtgaa
ctagctaaacagcttcatccaaaggaaaatgatttggtgttcttggttcccgaaagacta
aatgaagagaagaaggatctacagagaaactttgtgctggatccccacgaatatcactgt
ggttatgttcataaatttcgccgcacttcagtcatgcgtaatgggaagtctgagtgttcc
gtttccatccagactcaagataacttaccagtcagtttaagtgaattcgtgaaatgtatt
gtaattagctctctggtaacgacacaaaggaagttgaaagccatgtctttgctgagtggt
cggaaccaactggccagagccgttctgaatccaaaccccatggacttctgtacaaaagat
ttactaactacaacatctgagagaattatcgcctacttaagagatttcaacgaagaccaa
aagaaagcaatagaaactgcatatgccatggtgagacactccccatcggttgccaagatc
tgtctgattcatggaccacctggcacaggaaagtcaaaaaccattgtcggcctcctgtac
cgcttactgacagagaggaggggacactcagatgaaaactccaatgccaagatcaaacaa
aaccgtgtccttgtgtgcgcgccttccaatgcagctgttgatgaactcatgaaaaaaatc
atcctcgaattcaaagaaaaatgtaaagacaagaagaatcctttgggaaactgtggagat
ataaatttagtacgtctgggtccagagaagtctattaataatgaggtcctaaaattcagt
ttggacagccaggttaaccaccgaatgaagaaagagttaccttcccatgttcaggagatg
cacagaaggaaggaatatctagaccgtcagctggatgagctttcccgccggcgtgcgtta
tgccgaggggggcgggaagtacagaggcaagaattagatgaaaaaattgccgaagtttca
aaagaaaggcaggaacttgcttctaaaattaaagaggttcaaggacgcccacagaaaaca
cagagcatcatcattttggagtcccacatcatctgctgcacgctgagtacgagcggtggt
ttactgctcgagtctgcttttcgtggccaagggggtgtccccttcagttgtgtcattgtc
gatgaggctgggcagtcttgtgaagttgaaacgcttactccactcatccatcgttgcaac
aagcttatccttgtaggagatcctaaacagctccctcccacagtcatctctatgaaggca
caggagtatggctacgaccagtcgatgatggcccgcttctacaagctgctggaggagaac
gtggagcacaacatggtgggcaggctgcccgtgctgcagctgactgttcagtacaggatg
catcccgacatatgtctcttcccgtctaattacgtttacaacagaaacttgaagacaaac
agactgacagagaccaatcggtgttcgtcagactggccatttcagccctacctcgtgttt
gatgttggggatggttcagaaagacgggataatgagccagcggaagtcgataccgtggat
gcgttccagggtcgtcagaaagactgtgttattgttacctgtgtcagagcaaatgccatg
cagggctcaattggattcctggcaagtttgcagagattgaatgtcaccatcacacgagcc
aagtacagccttttcatcctcggacatttgaggaccctgatggaaaatcagcattggaat
cacctgattcaggatgcgcagaagcggggtgccattattaagacttgcgacaaaaactat
agacatgatgcaatgaagatcctgaaactcaagcccatgctgcagagaagtctgactcac
cctcctgccgtctccccagaggcatccagaccccagggtggcttgcccagcagcaagcta
gacagtgagtttgccaagacatcttttacttcttctgtatacctctcaccctctgactcc
aaagaagccactgttactgcaaaggaccctgaaaggccatctattcaggaccggcttcgg
gacccacgactgctgaggcggtttggcttgatccctgaagccaaagagcagtgtctctgg
gagccgcagccccccagcccccagcctcctggagcagcgcctccctcaggagagccgggc
tcccctggcagccaccagggtccggctggtacggggcagcagtccgccgccaaaggggcc
gctccgagcaaccacagacctcacgcgcagtgcgaccctccagctgctagtgctgacgct
cccacgagtaaaagaaaatgtgaccaggaagaggggctcagccacagaagagagaccagg
gctttcagtgaaggggatcaagagaggtgtggctctgggagccatcatccaaagaggaac
tcgggcttggatgagaggggactggagaaggaggacagtagcttgaagaggaggaggctg
ctgtag
DBGET
integrated database retrieval system
