KEGG   Vicugna pacos (alpaca): 102525703
Entry
102525703         CDS       T08098                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc04010  MAPK signaling pathway
vpc04020  Calcium signaling pathway
vpc04022  cGMP-PKG signaling pathway
vpc04114  Oocyte meiosis
vpc04218  Cellular senescence
vpc04310  Wnt signaling pathway
vpc04360  Axon guidance
vpc04370  VEGF signaling pathway
vpc04380  Osteoclast differentiation
vpc04625  C-type lectin receptor signaling pathway
vpc04650  Natural killer cell mediated cytotoxicity
vpc04658  Th1 and Th2 cell differentiation
vpc04659  Th17 cell differentiation
vpc04660  T cell receptor signaling pathway
vpc04662  B cell receptor signaling pathway
vpc04720  Long-term potentiation
vpc04724  Glutamatergic synapse
vpc04728  Dopaminergic synapse
vpc04921  Oxytocin signaling pathway
vpc04922  Glucagon signaling pathway
vpc04924  Renin secretion
vpc05010  Alzheimer disease
vpc05014  Amyotrophic lateral sclerosis
vpc05020  Prion disease
vpc05022  Pathways of neurodegeneration - multiple diseases
vpc05031  Amphetamine addiction
vpc05152  Tuberculosis
vpc05163  Human cytomegalovirus infection
vpc05166  Human T-cell leukemia virus 1 infection
vpc05167  Kaposi sarcoma-associated herpesvirus infection
vpc05170  Human immunodeficiency virus 1 infection
vpc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
vpc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102525703 (PPP3CA)
   04310 Wnt signaling pathway
    102525703 (PPP3CA)
   04370 VEGF signaling pathway
    102525703 (PPP3CA)
   04020 Calcium signaling pathway
    102525703 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    102525703 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102525703 (PPP3CA)
   04218 Cellular senescence
    102525703 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102525703 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    102525703 (PPP3CA)
   04660 T cell receptor signaling pathway
    102525703 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    102525703 (PPP3CA)
   04659 Th17 cell differentiation
    102525703 (PPP3CA)
   04662 B cell receptor signaling pathway
    102525703 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    102525703 (PPP3CA)
   04921 Oxytocin signaling pathway
    102525703 (PPP3CA)
   04924 Renin secretion
    102525703 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    102525703 (PPP3CA)
   04728 Dopaminergic synapse
    102525703 (PPP3CA)
   04720 Long-term potentiation
    102525703 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    102525703 (PPP3CA)
   04380 Osteoclast differentiation
    102525703 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102525703 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102525703 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    102525703 (PPP3CA)
   05163 Human cytomegalovirus infection
    102525703 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102525703 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102525703 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102525703 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    102525703 (PPP3CA)
   05020 Prion disease
    102525703 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    102525703 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    102525703 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102525703 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:vpc01009]
    102525703 (PPP3CA)
Enzymes [BR:vpc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     102525703 (PPP3CA)
Protein phosphatases and associated proteins [BR:vpc01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     102525703 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 102525703
NCBI-ProteinID: XP_006208984
LinkDB
Position
2
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgacggacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacggcaaaagaagtctttgataacgatgggaaa
cctcgagtggatatcctaaaggcacatctcatgaaggagggccggctggaagagagtgtt
gcgttgagaataataacagagggggcttccattcttcggcaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgtggggacatccatggacaattcttcgacttgatgaag
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagagcgtgtctatgacgcctgcatggat
gcctttgactgcctgcccttggctgccctgatgaatcagcaattcctgtgtgtacatggt
ggtttgtctccagagatcaacactttagatgacatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcaggggatgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatccatactccgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaacatcaggcaattcaactgttctcctcatcca
tactggcttcccaatttcatggatgttttcacttggtccctgccatttgttggggagaaa
gtgaccgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagaa
gaagatggatttgatggagccacggccgcagcccggaaggaggtgataaggaacaagatc
agagccattggcaagatggccagagtgttctcggttctcagagaagagagtgagagcgtg
ttgacgctgaaaggcctgacgcccacgggcatgctccccagcggagtgctctctggaggg
aagcaaacactgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggcgctcgcctcagagactaacggcacggacagcaatggcagtaacagcagcaatatc
cagtga

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