Vicugna pacos (alpaca): 102526502 Help Entry 102526502         CDS       T08098                                  Symbol MDN1 Name (RefSeq) midasin isoform X2   KO K14572   midasin Organism vpc  Vicugna pacos (alpaca) Pathway vpc03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:vpc00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     102526502 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:vpc03009]     102526502 (MDN1) Ribosome biogenesis [BR:vpc03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     102526502 (MDN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_16 AAA_7 AAA_22 TsaE nSTAND3 Sigma54_activat Sigma54_activ_2 AAA_18 AAA_14 ABC_tran NACHT AAA_2 AAA_6 DUF815 MDN1_4th bpMoxR Dynein_heavy Rad17 Mg_chelatase AAA_25 PduV-EutP TniB ResIII ATPase UPF0122 Motif Other DBs NCBI-GeneID:  102526502 NCBI-ProteinID:  XP_006200398 UniProt:  A0A6I9I210 LinkDB All DBs Position 8 AA seq 5600 aa AA seqDB search MEHLLLEVAAAPLRLIAAKNEKSRSELGRFLVKQVWTPQDRQCILNTLAQLLLDKDCAVL IGRQLRPLLLDLLERNAEAIKAGGQVNHDLHERLCVSMSRLVGNHPDVLPFALRYFKDTS PVFQRLFLESSDANPVRYGRKRMKLRDLMEAAYKFLQQEQSVFRELWDWSVCVPLLRSHD TLVRWYTANCLALVTCMNEEHKLSFLKKIFNSEELIHFRLRLLEEAQLQDLEKALVLANP EASIWRKEKGLQYLQGHLVSADLSPRVTAVCGVVLPGQPPAPREQASNRSSSREQELAFR SYVLVESVCKNLQTLAMAVASQNAVLLEGPIGCGKTSLVEHLAAMTGRRKPPQLLKVQLG DQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATKGHWILLEDIDYAPLDVVSVLIPLLEN GELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNMDKTE LNEVLQNRYPSLSAAADHLLDIYIQLTGEKHHSVSDSSVGGEQAPEEVSETRRENKRLTL EGRELSLRDLLNWCNRIVHSFDSLSSSASLNIFQEALDCFTAMLSKHTSKLKMAEVIGSK LNISKKKAEFFCQLYKPEIVINELDVQVGRVRLLRKQNEAVHIQREKLTFAATRPSSVLI EQLAVCVSKGEPVLLVGETGTGKTSTVQYLAHVTGHRLRVVNMNQQSDTADLLGGYKPVD HKLIWLPLREAFEELFALTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDG KESKTGSLLKEKWEAFGLRLNHAQQQMKMTENALLFAFVEGALAQAVKKGEWILLDEINL AAPETLECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRN RFTELYVEELESKEDLQILIVDYLKGLSVNKSTVQGIITFYAAVRKESGTKLVDGTGHRP HYSLRTLCRALRFAASNPCGSIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVSGNVK SLLKQPIPEPKGGRLIQVEGYWISVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPV LIQGETSVGKTSLIRWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLID AMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLITETQEVVKAHPRFMLFATQNPPGL YGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRGS SVFAGKQGFITLRDLFRWAERYRLAEQTEKEYDWLQHLADDGFMLLAGRVRKQEEVDVIQ EVLEKHFKKKLCPQSLFSKENVLKLLSKLSTQIPTLESKFSHIVWTEGMRRLAMLVGRAL EFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVNCHLHMETSDFLGGLRPVRQKPNDKE EIDTSRLFEWHDGPLVLAMREDGFFLLDEISLADDSVLERLNSVLEVERSLLLAEKGNIE DKDNEVELLTAGRKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISR NLRPGLSLGRTDHRGADIAEVMLDFIDWLTHQEFGRRCVVSIRDILSWVNFMNTMGEEAA LKRPETISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKKLSKIVRLTE CQKNELKIYDRLKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLL RATKLNKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDIADLFGADLPVEGGKG GEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHE KTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIDKNIVKKM VAFNNQIDHEVTVEKKWGQTGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGER MRTREDKEKIIAVFKDVFGSNLNPYMGTRLFHITPCDVQLGYSVLSRGNYVPPPTHRPLL LLHQSLQSLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAINSAMDTTE LLGGFEQVDLIRPWRQLLEKVEGTVRALLRDSLLVSADDAEVVLRAWSHFFLTYKPKCLG EGGKGVTMEIVNKLEAVLLLMQRLNNKISSYSKAEFAKLVEEFRSFGVKLMQSASGRSHG TFEWVDSMLVRALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTVSERGMIDGSTPTI TPNPNFRLFLSMDPVHGEISRAMRNRGLEIYIPGEGDRSIPDALDLKVLLHSLGLVGDSV CDTLLALHTETRSAVVGSPASSVSTLIQTAVLIVQYLQRGLSLDRAFSEACWEAYVRSQH SPANQQLVHALLEKHVSSLRAHETWGSSILAMGLWPDSLPSALFATEDSHLSKVRSDGQI LAYCLNRLSMKTSSWARIQPLTLPDLEKIMQSSHPESLKFSSVEMDTYWIDEPDALAMAV KLLIERATNQDWMLRVKWLYHLAKNMPQGLESIQIHLEASAASLRNFYSNSLSSGVSNVI KILQPNVTDEFVIPLDPRWNMQALDIIRNSMDFDPQTDQPEQLFALLESVANKTIIYLDR EKRIFTEANLISVGGKKLRNSVLRMSFEFHKDPESYHSLPHEIVVNLAAFFELCDALVML WVQSSQGMVSDASVNKILGSVQWRDRFWSVADSVKVDAPGLALLALHWHWVLKHVVRQIP QLLMNHEDKYYKEVQTVSEHIQNCLGSPTGGFTGVKKLQKFLGRPFPFKDKLVVECFSQL RIFNKALAIRERMLALGESGWREDVSRLQVAASEWTLKKSLLQAWGLVLRANILEDVNLD ELKDLMNAQCLELKAKGISLGFLEKKHNEASSVSQPDFTSLIQLTRRVQLWPAMEYLAVL WQYKVTADFMTRACLRRSSKNQQPQIDEEISHHITFCLKHTPVALQELRDLWSLQHHQKM STEEMISLWSELFNSTFMSFWSSTVTTNPEYWLTWSPLPDVQQREMPKFLLDSTLKGPGS LGRAVFSKCCFEVLTSSCRASPWDVSGLPILSSLHVTLGEWVEKAQQLRDISSVLWTNMA VPSVAEFRRTDSQLQGLVLCRHLAGLAELLPEPRRQEYLQNCQQLLLGDSQAFQHVGQTL GDMAGQEELPKELLCLLLTSLRHLFGDGEGKRDLPEPARRGSLWVSLGLLQIQTWLPQAR FDPAVKREYKLKYAKEELHQLQCEWKTRNLSSQLQTGRELEDEVILNHSHPHVRLLRQRI DHLENLICSLSKKQAFRPQLPAYESLVQEIHHYITSIAKASAVQDLLARLLQALHVDGPR PAQAAQNLLKEEASWQQSHHQFRRRLAEEFALFPDSVAPLQASILQLQHGMRLVACEVHA SLHGSAVCADRLGALATSLLAFPSVDLTFPTYYAHADALCSVKSEEVLRGLGKLIKRSGG KELEGKGQGLCPTREQLLLNALLYLRSHVLCKGELDQRALQLFRHVCQEIINEWDEQERI AQEKAEQESSLYRYRSRSSRTALSEEEEEEREFRKQFPLHEKDFADILVESSLEEENGTS DGQEEEAITNPAILSQSSMKAVMLIHQQLCLSFARSLWYQQTPPTHGAEHYLSLFLSCYQ TGASLVTHFYPLMGVELNDQLLGSQLLACTLSHNTLLGEGTSDLLVKPDGPYDFYQHPNI PEARHCQPVLQGFSEAVRQLLQDWPEHPALEQLLVVMDRIRSFPLPSPISKFLNGLEILL AKAQDWEENASRALSLRKHLDLVSQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFSI YQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLMP QVEGKDSLCSVLWNLYHYYKQFLDQVQAKIVELRAPLEKELKEFVKISRWNDVSFWSIKQ SVEKTHRTLFKFMKKFEAVLNEPCRSSLLESDKEEQPDFLPRPTDATASEGSPIQSLNRA LRETLLARPAAAQATVPEQHQGAPLPMEGELLRRLPKLVHRMWKLCLTLMRGTPLPHLVE GLDQFTGEVISSVTELQSLKVDPSAEKEKQRSEAKHILMQKQRALADLFKHLAKAGLSYR KGLAWARSKNPQEMLHLHPLDLRSALSIVSSTQEADSRLLAEISSSWDGCQKYFYRSLAR HARLTAALAAPTKEMGVGNVERCKGFSAHLMKVLIRQRRSLTTLTEQWILLRNLLSCMQE IHGRLAGPPTYPVAFPPQDGVQQWTERLQHLAMQSQILLEQLSWLLQCCPGAGPAPGQGH DQTQGQPSAPDLEGPELTVRQLSGATLDLIPSDLSYPSPVPGSQLPAGCRMRKQDQLWQQ STVRLTEMLKTIQSVKADVDKIRQQSCETLFHSWKDFEVCSSGLSFLSQVSAHLQGLESL FILPGVEGEQTDSQMALVESLEYVRREINKATDDFTAWKTHLLAPGSQGGNQTLDDGLVE DFSGQMETAIRAILYAIQNLTERHSKKTESTDHTRTQEEEEAAGFERLQSGHLTKILEDD FWADVSTLHVQKIISAVSELLERLKSYGEDGLAAKHTFFTQSCCLLVRLVPMVSRYSDLV LFFLTVSLATHRSTAKLLSVLAQVFAELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIG EGEGLKDVSDKIENEEQAEDTFQKGQEKDKEDPDSKPDIKGEDNAIEMSEDFDGKMHDGE LEGQDEDDEKSDSEGGDLDKQMGDLNGEEADKLDERLWGDDEDEDDEEEEDSKTEETGPG MDEEDSELVAKDDNLDAGKSNRDKNQQDKKEEKETAEANDEGQGQDKINEQIDEREYDEN EVDPYHGNQEKLPEPEALDLPDDLNLDSEDKDGSEDTDHEGEEENPLEIKEKPMDSEETD REAEALNEETEAAQSEGEGQSPHEPEEGHGEEDQVEPEEEMDMGADDQDEDATQHPEENS EEEQPSAEDKDASEESADSHVPVDQGLQPQQEKEEEGENPDTEERVPEATERKEHDSCGQ TGLESVQSMQAVELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIARLASQKHTRKNTQ SFKRKPGQADNERSLGDHNERVHKRLKTVDTDSHAEQNPAQPQAQVEDAEAFEHIKQGSA PYDAQTYDVASMEQQQSAKDSNKAPEEEETEDPFLDTEEQEELRAVDTEQLRPEEVKSGT TARLGFEEMEMETQTGKTEEDQDPRTDTSHKETENEKPERSRESTIHTAHQFLVDTTFQP FLKDVNELRQELERQLETWQPHESGNPEEEKAAAEMWQSYLVLTAPLSQQLCEQLRLILE PTQAAKLRGDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMV DNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKF QQKKTKIAQFLESVAGMFAAAQQLSQNVSPDTAQLLLVVSDGRGLFLEGKDRVLAAVQAA QNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPFYIILRDVNALP ETLSDALRQWFELVTASDQP NT seq 16803 nt NT seq  +upstreamnt  +downstreamnt atggagcaccttttgctggaggtggcggccgcgccgctgcggttaatcgctgccaagaac gagaagagccgcagcgagctgggcaggttcttggtcaagcaggtgtggacaccgcaagat cgccagtgtatcttgaataccttagcacagttactcctggataaggactgtgctgtgctg attggccgccagctgcgccctctccttttggatttattggaaaggaatgctgaagccatt aaagccggaggccaagtcaaccatgatttacatgaacggctctgtgtgtcaatgagcaga cttgtcggtaaccaccctgacgtcctcccgtttgctctcagatatttcaaggacacttct ccagtctttcaaagactcttcctagagagttcggatgcaaatccagttcgctatggacgc aagcggatgaagctccgggacctgatggaagcagcttacaagtttctgcagcaagagcag tctgtgttccgggagctctgggactggagtgtgtgcgtccctctcctcagaagccatgac accttggttcgctggtacacagccaattgtcttgctttagtcacctgtatgaatgaagaa cacaagttatcattccttaagaagatttttaatagtgaggaactgatccatttcaggctg aggttactagaagaggcccagctgcaggacttggagaaggccttggttttggccaatcca gaagcctccatttggcgtaaggagaaggggctgcagtacttacaaggacaccttgtttca gctgacctctcccccagggtgactgctgtctgtggtgtggtgctgcctgggcagccgccg gcccccagagaacaggctagtaataggagttcttctcgtgaacaggagctggcctttagg tcctatgtgctggttgaatcagtctgcaaaaatcttcagactctggctatggcagtggct tctcagaatgctgtgttattggaaggaccaattggatgtggcaaaacttccctagttgaa catttagctgcaatgacaggtagaaggaagccccctcagcttctcaaagtccagcttgga gatcagactgacagtaagatgctgttgggaatgtatcgctgcacagatgtcccaggagag tttgtgtggcagcctggcaccctgacacaggcagccacaaaaggacattggatccttctg gaagatattgactatgcccccttagacgtggtttctgtgctgatccctcttttggagaat ggagagctcttgattcctggccgaggggactgtctgaaagtggctcctggatttcagttc tttgcaaccaggaggctcttgagctgtggaggaaattggtatcgaccactgaatagtcat gcgactctgttagacaaatattggaccaaaattcacttggataacatggataagacagaa ctgaatgaggttcttcaaaacagatatcccagtttatcagcagcagccgatcacctgctt gacatttacatccagcttactggagagaaacatcactctgtgagtgatagttctgttgga ggggaacaggcacccgaagaagtttcagaaaccagaagagaaaataaaagactgaccctt gaaggaagagaattgtctctacgggatctactgaattggtgtaatagaattgtccacagc tttgacagtctgtcttcatcagcatcattaaatatttttcaagaggctttggactgtttc acagcaatgctttctaagcatacaagcaaactgaaaatggcagaagtcattggaagcaag ttgaacatttccaagaaaaaggctgaattcttctgtcaactttataaaccagaaattgtg atcaatgagttagatgtgcaagtgggtcgagtgcggcttcttcggaaacaaaatgaggct gtccacatacagagggagaagctcacctttgctgctacgaggccgtcctccgttcttatt gaacagcttgctgtgtgcgtcagcaaaggggagcccgtgttgctggtgggagagaccggc actggcaaaacctccactgtccagtacttggctcatgttacaggccaccgtttgagggtt gtcaatatgaatcaacaaagtgacactgcagacttgcttggaggttacaaaccagtggac cataagcttatttggctacccttacgggaggcatttgaggaactctttgctctgacattt tccaagaagcaaaactttacatttttgggacacattcagacctgttaccggcagaaacgg tggcatgatctcctcagattaatgcagcatgtgcacaagtcggctgtcaacaaggatgga aaagagagtaaaactgggtcactactaaaagagaagtgggaagcatttggtcttaggctc aaccatgcacaacaacagatgaaaatgactgaaaatgccttattgttcgcatttgtagag ggtgcattagctcaggctgtaaagaaaggagagtggatcttgttggatgagattaatctg gctgctccagaaacattagaatgtctgagtggtttacttgaaggctcctctggctccctg gtgttgctggatcgaggagacacagaaccactggttcgccatcctgacttccgcttattt gcgtgtatgaatccagcaactgatgtgggtaaaagaaatctcccaccaggaataagaaac aggttcacagaactctatgtagaagaattagaaagtaaagaagacttacagattcttatt gtggattatctgaaaggattgagtgtgaacaagagcacagtgcaaggaatcataactttc tatgcagctgtgcggaaagaatctgggacaaaattggtggatggaaccggccatagacct cactacagccttcggactctctgtagggccctgcgatttgcagcctccaatccatgtggc agcatccaacgctctctctatgagggcttttgtttgggtttcttaacacagcttgacagg gcatcacatccaatagttcagaagctcatttgtcaacacattgtctctggcaatgttaaa agtctgctgaaacagcctattccggaaccaaaagggggtcggcttatccaggtggaaggc tactggatttcagtgggagacaaggaacctacaatagatgagacgtacatccttacctct tctgtcaagctgaacctgagagatatagtccgagtggtctctgcaggaacctatccagtg ctgattcagggagagacatcagttggtaaaacaagcctgatccggtggctggccgcagct actggtaaccactgtgtgcgtattaacaaccatgaacacactgatattcaggagtacatt ggttgttacacatctgactcctcagggaagcttgtgtttaaagaaggtgtccttattgat gctatgagaaagggctattggattattttagatgagttaaatttggcccctaccgatgtg ctagaggcattgaacagactgttggatgataaccgggaattgctcataacagaaacacaa gaagttgttaaagctcaccctcgcttcatgctttttgccacccagaatcccccaggactt tacggaggcagaaaggtgctttctagagccttcaggaatcggtttgtggaactgcacttt gacgaattgcctagttctgagttggaaacgatcttgcacaagcgatgtagtttgccaccc tcctactgcagcaagttggttaaagtcatgctggaccttcagtcctatcgcagaggttct tcagtgtttgctggaaagcagggcttcatcaccctccgtgatctgtttcgatgggctgag cggtacagattggccgaacagacagagaaggagtatgactggctgcagcacttagctgac gatggttttatgcttctggcaggtcgagtcaggaagcaggaggaggttgatgtgattcaa gaagtccttgaaaaacatttcaagaaaaaattatgtcctcaatccctcttctccaaagaa aatgtcctaaaattgctgagtaaactgtctactcagatacccacattggagtctaagttc agccacatcgtgtggactgagggcatgcggagactggcgatgctagtgggaagggcattg gaatttggagaaccggtgctgctggttggagatactgggtgtgggaaaaccactatctgt caggtgtttgcagccttggcaaatcagaaattgtactcagtcaactgccacttacacatg gagacatcagacttcctgggggggctgcgaccggtgagacagaagccaaatgacaaggaa gaaattgacacatcaagactctttgagtggcatgatggaccgctggttctggccatgaga gaggatggctttttcctcttagatgaaatctcactggctgatgactctgtcctggaaaga ctcaacagtgtccttgaagtggaaaggtctctgttactagctgaaaaaggcaacatagag gacaaagataatgaagtggagctgttgactgctgggagaaaattccgtatcttggcaacc atgaaccctgggggtgactttgggaaaaaagagctatctcctgccttaagaaaccgtttt acagaaatttggtgtcctcaaagcacaagccgtgaagatttaattcagattatcagccgc aatcttcgcccaggattgtctctgggcagaacagatcatagaggggctgacatagctgag gtgatgctggatttcattgactggctgacccaccaggagtttggccgaagatgtgtggtc agtatcagagatatcctgtcctgggttaacttcatgaacacaatgggggaggaagctgct ttgaaaaggccagagaccatctccactgtgacgtcttttgtccacgccgcatgcctggtg tacatagatggaataggttcaggggtaacttcctctgggtttggtacggcacttttggct cgcaaagaatgtctgaaattcctaatcaagaaactttccaagatagtccgacttacagaa tgtcagaaaaatgaattgaagatttatgacaggctcaaagccaaagaattcactgggata gataacctttggggaattcatccattttttataccaaggggacctgtcctgcacaggaat aatatcgctgactatgcactcagcgcaggcaccacagctatgaatgcccagaggctttta agagctaccaaactgaacaaacctatcctcctggagggctcccccggtgtgggcaagacg agcttggtgggagcattagcaaaggcttcaggcaacacccttgtccgaatcaacttgtca gagcagacggacatcgcagacctttttggagcagatctacctgttgaaggtggcaaggga ggagagtttgcctggcgcgatggccccttgctggcagccctgaaagcaggccactgggtt gtgttggatgagctgaacctggcttctcagtcagtcttggaaggactcaatgcttgtttt gatcaccgaggagaaatctatgttcctgagttaggaatgagctttcaagtgcagcatgaa aagacgaagatttttgggtgtcaaaatccttttagacaaggaggtgggaggaagggcttg cccaggtctttcctaaacagattcactcaggtctttgtggatcccctcacagtaattgac atggagtttattgctagtactctgtttccagcaattgacaaaaatattgttaaaaaaatg gttgctttcaacaaccaaattgatcatgaagtgactgtcgagaagaaatgggggcaaaca ggaggaccctgggaattcaacctccgggaccttttccgctggtgtcagttgatgctagtt gaccagtcccctgggtgttatgatcctgggcagcatgtgtttttggtctatggcgaaaga atgagaaccagggaagataaagaaaagatcattgctgtattcaaggatgtgtttggttca aatttgaacccatacatgggaaccagactatttcacatcactccctgtgatgttcagctg ggctactcagtgctttcccgcggcaactatgtccctcccccgacccaccgtcccctgttg ctcctgcaccagtctttacagtctctggagtcaattatgaagtgtgtacaaatgagctgg atggtcatccttgtgggcccagcctcagtgggcaagaccagcttggttcagctcctggca caccttactggtcacacgttaaagatcatggccataaacagtgcaatggacaccacggag cttctgggtggatttgagcaggtggatcttatacggccatggaggcagctcctcgagaag gtggagggcactgtaagggcactgttaagagacagcctcctcgtcagtgctgatgatgca gaagtagtgttgcgagcctggagccatttcttcttgacatataagcccaagtgtcttgga gaaggtggtaaaggtgtcacgatggagattgtcaacaagctcgaagcagtgttactgctt atgcagagactcaacaataaaatcagttcatactccaaggcagagtttgccaaactcgtg gaagaattccgaagttttggggtgaagcttatgcagtcagccagtggccgcagccatggc acgttcgaatgggttgacagcatgctggttcgggccctgaagtctggagattggcttttg atggacaatgttaacttctgcaacccatcggtgctggatcgtttgaacgctttgcttgaa cctggaggtgttctcactgttagtgagagaggaatgattgatggatccactcccaccata acaccaaatccaaatttcaggctttttctctcaatggatcctgttcatggagaaatatct cgagctatgaggaatcgtggacttgaaatctacattccaggagaaggagacaggagcatc ccagatgccctggatttgaaagttctactgcacagccttgggttggtgggggacagtgtg tgtgacaccctcttggctttgcacacagagacccgaagtgctgttgtaggttctccagca tcctctgtgtcaactctgattcagacagccgtactcatcgtgcagtacctacagcgaggg ctgagcttggacagagccttttctgaagcgtgctgggaggcctatgtccgctcccagcac tcaccagccaaccagcagcttgtgcatgctttattggagaaacacgtttcttctctgcga gcacatgaaacctggggtagctccattcttgccatggggctgtggccagattctctgccc tcagctctctttgctacagaagattctcacctttctaaagtccgaagcgatgggcagatc ttagcatattgtctcaacagactgagcatgaaaacaagcagctgggcaaggattcagcct cttactttgccagatttagagaaaattatgcagtcctcccacccggagagcttgaagttc agttcagttgaaatggatacttactggatcgatgaaccagatgctctggccatggctgtt aagttgctcatagaaagagcaaccaatcaagattggatgctcagagttaaatggctttat catttagccaaaaatatgccacaggggcttgagtcaatacagattcatttggaagccagt gctgcatctcttaggaatttttactcaaattctctctcatctggggtcagtaatgtcatc aaaatattacaaccaaatgtaacagatgaatttgtgatccctctggacccccgatggaat atgcaggctttggacatcattagaaattcgatggattttgacccacaaacggaccagcct gagcagctctttgctcttttagagtctgttgcaaacaagacaatcatatatcttgaccgg gaaaaacggatttttactgaagcaaatttgatttctgttggtggcaaaaagttgagaaat agtgttttgagaatgtcctttgaattccataaagatccagagagctatcacagcctgcct catgaaatcgtggtcaatcttgctgctttttttgaactttgtgatgcactagtcatgctc tgggtacagtcctcccaggggatggtgtctgatgccagtgtcaacaagatcttgggttct gtgcagtggcgggaccgattttggagtgtggctgactcagtaaaagtggatgccccaggc ctggccctgcttgcccttcactggcactgggttttaaaacatgtggtccgtcagatcccc caactcctgatgaaccatgaagacaaatattacaaagaggttcagaccgtctcagaacac atacagaactgcttggggagcccaaccggaggattcactggtgtaaagaagttgcagaag ttcctaggacgaccgtttccttttaaggacaagctggtggtggagtgtttttcacaactg agaatctttaacaaagcccttgccatcagggagcggatgcttgcccttggggagagtgga tggcgggaagacgttagtcggctccaagtggctgcttctgagtggacattaaagaaaagt ctcctgcaagcttgggggctggtcctcagagctaacattctggaagatgtcaacctggat gaattaaaggatctcatgaatgctcagtgtttagaactaaaagccaaaggaatttcactt ggttttctggagaaaaaacataatgaagcttcctccgtgtcccagccagactttacctcc ttaatccagctcaccaggcgtgttcagttgtggcctgcaatggagtacctggctgtgctt tggcagtacaaagtgacagctgattttatgacacgggcttgtctgagaaggtccagcaaa aatcagcaaccccagatagatgaggagataagtcatcacatcaccttttgtcttaagcac acgccagttgctctacaagagcttcgagacctttggtccttacagcaccatcaaaagatg tctactgaagaaatgatctctttgtggtccgagttatttaattccacgtttatgtctttc tggagcagtactgtgaccacaaatccagagtactggctcacatggagccctctgcctgat gtgcagcagagggagatgcccaagttccttttggactccacattgaagggtcctggcagt ctcggtagagccgttttctccaagtgctgcttcgaagtcttgaccagcagctgtagagca agtccctgggatgtgagcggcctccctatcctgtcctccttgcatgtcacgcttggggag tgggttgagaaagcccagcaactccgggacatcagctcggtgctttggaccaacatggct gtcccttcagtagcagagttcagacgcacggattcccagctccaggggctggtgctgtgc cggcacctggccggcctggcggagctgctccccgagccccggcggcaggagtacctacag aactgccagcagctgctgcttggggacagccaggccttccagcatgttggccagactctc ggggacatggccgggcaggaggagctgcccaaggagctgctgtgtctcttgctcacctcc ctgcgccacttgtttggggatggggagggtaagcgggacctgcctgagccagcccgccgt gggagcctgtgggtgagccttggcttgctccagatccagacctggcttccccaggcacgc tttgaccccgccgtgaagagagaatacaagctcaagtatgccaaggaagagttacaccag ctgcagtgtgaatggaagacccggaacctctcatcccagctacagaccggaagagagctg gaggatgaagttattctcaatcactctcatcctcatgtcaggttgcttcgccaaagaatt gatcacctggagaatttaatctgcagcctgtccaagaagcaggccttcaggccccagctg cctgcctacgagtccctggtgcaggagatccaccactacatcaccagcattgccaaggcc tctgctgttcaggatctgctcgcgcggctcctgcaggccctccacgtcgacggacctcgg cctgcccaggcggcccagaacctcctgaaggaggaggcctcctggcagcagtcgcaccac cagttcaggaggcggctggccgaggagttcgcccttttcccggactctgtggccccgctg caggcatccatcctgcagctgcagcacggcatgcggctggtggcatgcgaggtccacgcc tcgctccatggcagcgcagtctgcgcggacaggctgggtgccctggccacatccctgctg gctttcccatcggtggacctcactttccccacctactatgctcacgcagatgctttgtgc tcagtgaagtcggaggaggtgctgcgaggccttgggaagctgatcaagcgctcgggagga aaggaactggaaggcaagggccaggggctctgccctacccgagaacagctgctgctgaac gccctcctttacctgcgctcccacgtgctgtgcaagggagagctggaccagcgggccctg cagctcttcagacacgtgtgtcaggaaatcatcaatgagtgggacgaacaggaacgcatc gcccaagagaaggccgagcaggaaagcagcctatacagataccggagcaggagctccaga acggccctgagcgaggaggaggaggaggagcgggagttcaggaagcagttcccgctgcat gaaaaggacttcgcagatattttggtagaatcatcactggaggaggaaaatggaacttca gatgggcaagaagaggaggccataaccaaccccgccatcctgtcccagagctcaatgaag gctgtgatgctgatacaccagcagctgtgtctcagctttgctcggtccctctggtaccag cagactccaccaacacacggggcagagcactacctcagcctgtttctgtcctgttaccag actggagcatctcttgtgacacacttctaccccttgatgggagttgagctgaatgaccag ctcctgggcagccaactcttggcctgcaccctgtcccataacactctccttggggagggg acctcggacctgctagtgaagcctgacgggccctatgacttctaccaacaccccaacatc ccggaagctcggcactgtcagcctgtgctacaaggcttctcagaggctgtcaggcagctg ctacaggactggccagagcacccagcgctggagcagctgctggttgtaatggacagaatt cgtagcttcccacttcctagtcccatctcaaagttcctgaatggcttagagatcctcctg gcaaaggcacaggattgggaggagaatgcaagtcgagctctgtctctgcggaaacatctt gatctggtcagtcagatgatcatccgttggcgtaaactggaactgaactgctggtctatg agtttggataacaccatgaagcgccacactgagaaatccaccaagcactggttctccatc tatcagatgcttgagaagcacatgcaggaacaaacagaggagcaggaagatgacaaacag atgaccctgatgttgctggtcagcacgttacaagcatttattgaaggatcttcactggga gaattccacgtacgacttcagatgttactggttttccattgtcatgtcttgctgatgcca caagttgaaggaaaagattcactttgcagtgttctgtggaatttgtaccattattacaag caattcttggaccaagttcaggccaaaattgtggaacttcgtgcccccctagaaaaagag cttaaagaatttgttaagatatccaggtggaatgatgtcagcttctggtctattaaacaa tctgtggaaaaaacacacaggaccctctttaaattcatgaagaaattcgaagctgtcctg aatgaaccctgccggtcatccctgctggagagtgacaaggaggaacagcctgactttttg ccaaggccaacagatgcaaccgcgagtgaggggtcccccattcagagtctgaacagggcc ctgagggagaccctgttagcccggccagcagctgcacaggccacggttccagaacagcat cagggtgctcctctccccatggagggggagcttctgcgccgcttgccgaagctcgtgcac cgaatgtggaagttgtgcctgacgctgatgaggggaacccccctgccccacctcgtagag ggcctggaccagttcaccggcgaggtaatttcctctgtaactgagctgcagagcttaaag gtggatccctctgcagagaaggagaagcagcgatcagaagccaagcacattctcatgcag aagcagcgagctttagcagacctctttaaacacctcgcaaaagccggtttgtcatatcgc aaaggtcttgcctgggcccgttcaaaaaaccctcaagagatgcttcatctccacccattg gatctccgaagcgcactgtctatagtcagcagcactcaggaggctgattctaggctgctt gcagaaatctcatcttcgtgggatgggtgccagaaatatttctaccgctcccttgcgcgg cacgccaggcttactgcggccttagcagctcctaccaaggagatgggcgtgggcaacgtg gagcggtgtaaagggttctcggcgcacttgatgaaggtgctgatccgacagcggcgctcc ctgaccacgctgacggagcagtggatcctcctcaggaacctcctcagctgcatgcaggag attcacggcaggctggcagggccacccacctaccccgtggccttcccgcctcaggatggg gtgcagcagtggacggagaggctgcagcacctggccatgcagagccagatcctgcttgag cagctctcctggctcctccagtgctgccccggtgcaggcccagctccaggccaaggccat gaccagacacagggtcaaccttctgcccccgacctagaaggcccagagctcaccgtgagg cagctttccggtgcaacgctggaccttatcccgtcagatctaagctacccatccccagtt cctggaagtcagctgcctgctggttgccggatgcggaaacaggaccagctttggcaacag tcaactgtgagattaacagagatgctgaaaaccattcagtcagtgaaagctgatgtcgac aaaattaggcagcagtcttgtgagactctgtttcattcttggaaagattttgaagtttgc tcttctgggctgagtttcctgtcccaggtgtcagctcatttgcaaggcctagagtccttg ttcattcttccaggggtagagggagagcaaacagactcacaaatggcattagttgagagc ctggaatacgtaagaagagagatcaataaagccacagatgactttactgcctggaagaca cacttgctcgccccaggcagccaaggaggaaaccaaacgctggatgatggacttgtggag gatttttcagggcaaatggaaactgccatccgggccatcctttatgccatccagaactta acagaaagacacagtaagaaaacagagagcactgaccacacaaggacacaagaagaggag gaggcagcaggctttgagagactgcagtcaggacatctaaccaaaatcttagaggacgac ttctgggccgacgtgagcactttgcacgtgcagaaaataatttccgccgtctctgagctg ttggagaggctgaagtcatacggcgaggatggcttagcggccaagcacacgttcttcacc cagtcctgctgcttgttggtgcgcctggtgcccatggtctccaggtactcagaccttgtc ctcttcttcctgaccgtgtccttggcaactcaccgcagcactgccaagctgctctctgtg ctcgcccaggtctttgcggagctggctcagaagggattttgcctgcccaaagaatttatg gaggattcagcaggagagggagcaactgagttccacgactacgagggaggtggaattgga gaaggcgagggcttgaaggatgtgagtgacaagatagaaaatgaagagcaggcagaagat acatttcagaagggccaagaaaaggataaggaagatcctgactcaaaaccagacattaag ggcgaggataatgccatcgagatgtcagaagactttgatgggaaaatgcacgatggggag cttgaaggacaagatgaggatgatgagaaatcagacagtgagggcggagacctggataaa cagatgggtgacctgaacggtgaggaagctgacaaactagatgagaggctttggggtgat gacgaagatgaggacgatgaggaggaagaagacagtaaaactgaagaaacaggaccagga atggatgaggaagattctgaacttgttgctaaagatgacaacttagatgctgggaagtca aacagagataaaaaccagcaagataagaaggaagaaaaggaaacagcagaagctaatgat gagggacaaggccaagataaaattaatgaacagatagacgagagggaatacgatgagaat gaggtggacccttaccatggcaaccaggaaaaactgccagaacctgaggccttggacctt ccggatgacttaaacctggacagcgaagacaaggatggcagtgaggacacagaccacgaa ggagaagaagagaatcctttggagattaaagaaaaaccaatggatagtgaagaaacagat cgagaagctgaggcactaaacgaagagactgaggctgcccagagtgaaggtgaaggtcag agcccacacgagcctgaggaaggccacggggaggaggatcaggtggagccggaggaagag atggacatgggagctgatgaccaagacgaggatgccacccagcatcctgaagaaaactcc gaggaggagcagccatctgcagaggacaaggacgccagtgaggaaagtgcagacagtcac gtccctgtggatcaaggtctccagcctcagcaagaaaaagaagaagaaggggagaatcct gacactgaggagcgggtgccagaggccacagagaggaaggagcatgactcctgcgggcag acaggcttggagagcgtgcagagcatgcaggcggtggagctggccggggccgcgcccgag aaggagcaggggaaggaggaacacgggagtggagctgcggatgcaaaccaggcagaaggc catgaatccaacttcatcgcccggttggcctcccagaaacacaccaggaaaaacacacag agttttaagaggaaacctgggcaggctgacaatgaacgctccttgggagatcacaatgag cgtgtgcataagaggctgaagactgtggatacggacagccacgccgagcagaacccggcc cagccgcaggcccaggtggaggacgcggaggcatttgagcacattaagcaaggcagcgcg ccctatgatgcgcagacctacgatgtggccagcatggagcagcaacaatcagctaaggac tccaacaaggctccggaagaggaggagacagaggatcccttcttggacacagaggagcag gaggagctcagagcagtggacacagagcagctgagaccagaggaggtcaagtcggggacc acggcacgcctgggctttgaagagatggagatggagacccaaactggtaaaacagaggaa gaccaagaccccaggacagacacatcccacaaggagacagagaatgagaaaccagagaga agccgagagtcaaccattcatacagcccatcagttccttgtggacacgactttccagcct ttcttaaaagatgtcaatgaactaagacaggagctggagagacagctggaaacatggcag ccacacgaatctggaaacccagaagaagagaaggccgcagccgagatgtggcagagctac ctggtcctaactgcgcctctttcacaacagctgtgtgaacagcttcgtctcatactagag cccacccaggcggccaaactgagaggagactatcgaactgggaagcgactgaacatgcgg aaggtcattccatacattgctagtcagttccggaaagacaagatttggcttcgaaggacc aagcccagtaaacgccaatatcagatttgtttggctatcgatgactcttccagcatggtg gacaaccacacgaaacagcttgcttttgaatctttggccgtgattggaaatgctctaacc cttctggaagtgggtcagattgcagtgtgcagttttggagagtctgtaaaactgttacac ccattccatgaacagttcagtgactactcagggtcccagattctgcggctctgcaaattc cagcaaaagaaaaccaagattgctcagttcctagagtctgtggccggtatgtttgcagct gctcagcagctctcacagaacgtcagtccagacaccgcacagctcctcctggtggtctct gatggacgcggcctcttccttgagggcaaagacagagtcctagcagcagttcaggctgcc cagaatgctaacatctttgtcatttttgttgtgttggacaaccccagttcgcgggattct atcttggacattaaagtaccaatatttaaaggacctggagagatgcctgaaatccgatcc tacatggaagagttcccattcccattctacataattcttcgtgacgtgaatgcacttcct gagactctaagcgatgctcttaggcagtggtttgagctggtgacggcctctgaccaacca tag

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