KEGG   Vicugna pacos (alpaca): 102527219
Entry
102527219         CDS       T08098                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc01521  EGFR tyrosine kinase inhibitor resistance
vpc01522  Endocrine resistance
vpc04010  MAPK signaling pathway
vpc04014  Ras signaling pathway
vpc04015  Rap1 signaling pathway
vpc04066  HIF-1 signaling pathway
vpc04068  FoxO signaling pathway
vpc04081  Hormone signaling
vpc04114  Oocyte meiosis
vpc04115  p53 signaling pathway
vpc04150  mTOR signaling pathway
vpc04151  PI3K-Akt signaling pathway
vpc04152  AMPK signaling pathway
vpc04211  Longevity regulating pathway
vpc04213  Longevity regulating pathway - multiple species
vpc04510  Focal adhesion
vpc04550  Signaling pathways regulating pluripotency of stem cells
vpc04730  Long-term depression
vpc04750  Inflammatory mediator regulation of TRP channels
vpc04913  Ovarian steroidogenesis
vpc04914  Progesterone-mediated oocyte maturation
vpc04935  Growth hormone synthesis, secretion and action
vpc04960  Aldosterone-regulated sodium reabsorption
vpc05200  Pathways in cancer
vpc05202  Transcriptional misregulation in cancer
vpc05205  Proteoglycans in cancer
vpc05214  Glioma
vpc05215  Prostate cancer
vpc05218  Melanoma
vpc05224  Breast cancer
vpc05410  Hypertrophic cardiomyopathy
vpc05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102527219 (IGF1)
   04014 Ras signaling pathway
    102527219 (IGF1)
   04015 Rap1 signaling pathway
    102527219 (IGF1)
   04066 HIF-1 signaling pathway
    102527219 (IGF1)
   04068 FoxO signaling pathway
    102527219 (IGF1)
   04151 PI3K-Akt signaling pathway
    102527219 (IGF1)
   04152 AMPK signaling pathway
    102527219 (IGF1)
   04150 mTOR signaling pathway
    102527219 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    102527219 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102527219 (IGF1)
   04115 p53 signaling pathway
    102527219 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102527219 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    102527219 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102527219 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    102527219 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    102527219 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102527219 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    102527219 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102527219 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    102527219 (IGF1)
   04213 Longevity regulating pathway - multiple species
    102527219 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102527219 (IGF1)
   05202 Transcriptional misregulation in cancer
    102527219 (IGF1)
   05205 Proteoglycans in cancer
    102527219 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    102527219 (IGF1)
   05218 Melanoma
    102527219 (IGF1)
   05215 Prostate cancer
    102527219 (IGF1)
   05224 Breast cancer
    102527219 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102527219 (IGF1)
   05414 Dilated cardiomyopathy
    102527219 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102527219 (IGF1)
   01522 Endocrine resistance
    102527219 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:vpc04052]
    102527219 (IGF1)
Cytokines and neuropeptides [BR:vpc04052]
 Cytokines
  Growth factors (RTK binding)
   102527219 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 102527219
NCBI-ProteinID: XP_006205959
UniProt: A0A6I9IAZ3
LinkDB
Position
12
AA seq 159 aa
MGKISSLPTQLFKCCFCDFLKVKMHVTSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYQPPSTNKKTKSQRRRKGSTFEEHK
NT seq 480 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacgtcacgtcctcctcgcatctcttctacttggccctgtgcttgctc
accttcaccagctctgccacggctggacctgagacgctctgcggggctgagttggtggat
gctcttcagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcgcctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctgaggaggctggagatgtactgcgcacccctcaagcctgccaagtcagcccgctcc
gtccgtgcccaacgccacactgacatgcccaaggctcagaagtatcagcccccatctacc
aacaagaaaacgaagtctcagaggagaaggaaaggaagtacatttgaagaacacaagtag

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