Vicugna pacos (alpaca): 102528960
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Entry
102528960 CDS
T08098
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04217
Necroptosis
vpc04380
Osteoclast differentiation
vpc04620
Toll-like receptor signaling pathway
vpc04621
NOD-like receptor signaling pathway
vpc04630
JAK-STAT signaling pathway
vpc04658
Th1 and Th2 cell differentiation
vpc04659
Th17 cell differentiation
vpc05145
Toxoplasmosis
vpc05160
Hepatitis C
vpc05161
Hepatitis B
vpc05162
Measles
vpc05164
Influenza A
vpc05165
Human papillomavirus infection
vpc05167
Kaposi sarcoma-associated herpesvirus infection
vpc05168
Herpes simplex virus 1 infection
vpc05169
Epstein-Barr virus infection
vpc05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102528960 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102528960 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102528960 (TYK2)
04621 NOD-like receptor signaling pathway
102528960 (TYK2)
04658 Th1 and Th2 cell differentiation
102528960 (TYK2)
04659 Th17 cell differentiation
102528960 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
102528960 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
102528960 (TYK2)
05160 Hepatitis C
102528960 (TYK2)
05171 Coronavirus disease - COVID-19
102528960 (TYK2)
05164 Influenza A
102528960 (TYK2)
05162 Measles
102528960 (TYK2)
05168 Herpes simplex virus 1 infection
102528960 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102528960 (TYK2)
05169 Epstein-Barr virus infection
102528960 (TYK2)
05165 Human papillomavirus infection
102528960 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102528960 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102528960 (TYK2)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102528960 (TYK2)
Protein kinases [BR:
vpc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102528960 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102528960
NCBI-ProteinID:
XP_015096519
UniProt:
A0A6J3BGR4
LinkDB
All DBs
Position
22
AA seq
1183 aa
AA seq
DB search
MPLCHCGATTRSRKPDGDEAQPMATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILDISGDTSLTLHYRMRFYFRNWHGMNPQE
PAVYRCGPPGAEASSEQAEKGIQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMAFLHLCHLALRDGVPLEKVAKKISFKDCIPRSFRRQIQQHNALTRLRLRSIFR
RFLRAFQPGCLSQQVVMVKYLATLEQLAPRFGTERVPVCHLELLAQAEGEPCYIRDGGQA
SLDPESAPGPPTHEVLVSGTDGIQWRLIQAEGPCGGADGDSSRNPRAGPSGKKAKIQEEG
NQPADRPREALWAYFCDFQDITHMVLKERRVSIHCQDNKCLELTLPSRAAALSLVSLVDG
YFRLTADSSHYLCHEVAPPRLVLSIQDGIHGPLLEPFVLAKLQPEDGLYLIHWSTSHLNR
LILTVAQRDQASGPKGLRLRKFPIEVQAGTITLEGWDRPFPSVRELRAALQGCSLRAGND
CFSLRRCCLPRPGEISNLIIMRGSQASTRPLNLSHLSFHRVRQEDITQLSHLGQGTRTNV
YEGLLRVEGGGPKEDKAGGRDPATPDEGCGQDLRVVLKVLDPGHHDIALAFYETASLMSQ
VSHVHLVFVHGVYVHGSENIMVTEYVEHGPLDVWLRRERGHVPLAWKLTVAQQLASALSY
LEDKSLVHGNVCGRNILLARLGQAEGTSPFIKLSDPGVGLSALSREERVERIPWTAPECL
SGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPELATL
TSQCLTYEPAQRPSFRTILRDLTQLQPQNLFDVLSVNPDLPVSDPTVFHKRYLKKIRDLG
EGHFGKVSLYCYDPTNDGTGEMVAVKALKAGSGPQLRTGWRREIDILRTLYHEHIVKYKG
CCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYVHRDL
AARNVLLDNNRLVKIGDFGLAKAVPDGHEYYCVREDGDSPVFWYAPECLKECKFYYASDV
WSFGVTMYELLTYCDSSQSPPSKFIELIGHTQGQMMVLRLTELLERGERLPQPEKCPCEI
YLLMKNCWGTEASSRPTFQNLIPILKTVHEKYRSQAPSVFSVC
NT seq
3552 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattgcggggccaccaccaggagcagaaagcccgatggggacgaagct
cagcccatggccaccagaggaggcttgaaggttcttctacactgggctggccccggtggc
ggggagccctgggtcaccttcagcgaggctacactgacggcagaggaggtctgcatccac
atcgcacacaaagtcggcatcactccaccctgcttcaatctcttcgccctctttgatgcc
caggcccaggtctggctacctccaaaccacatcctagatatctctggagacacgagcctg
acgttgcactaccgcatgaggttttatttccggaactggcatggcatgaatcctcaggag
ccggctgtgtaccgctgcgggcccccaggggctgaggcttcctcagaacaggcagagaag
gggatacaactcctggacccagcctcctttgagtacctctttgagcagggcaagcatgaa
tttgtcaatgacgtggcatcgctgtgggagctgtcaagtgaggaggagatccaccacttt
cagaacgagagcctgggcatggccttcctgcacctctgccaccttgctctccgcgatggt
gtcccccttgagaaggtggccaagaagatcagctttaaggactgcatcccacgctccttc
cgacggcagatccagcagcacaacgcgttgacacggctgcgcctgcgcagcatcttccgc
aggttcctgagggccttccagccgggatgcctttcccagcaggtcgtcatggttaaatac
ctggccacgctggagcagctggcaccccgctttggcacagagcgcgtgcccgtgtgccat
ctcgagctgctggcccaggccgagggggagccctgctacatccgggatggcgggcaggcc
tctctggaccccgagtctgcccccggaccccccacccacgaggtgctggtgtcgggcact
gacggcatccagtggcggctaatacaggcagagggtccctgtggtggtgctgatggtgac
agcagcaggaatccccgtgctggcccatctgggaagaaagccaagatccaagaagagggc
aaccagccagcggacaggcctcgggaggcactgtgggcctacttctgtgacttccaggac
atcactcacatggtgctgaaagaacgccgtgtcagcattcattgtcaggacaacaagtgc
ctggagctgaccctgccttcccgggctgcggccctgtccttggtgtcattggtggatggc
tacttccgcctgaccgccgactcgagccactacctatgccacgaggtggctcctccacgg
ctggtgttgagtatccaggatggtatccatggacccctgctggagccattcgtgctggcc
aagcttcagcccgaggatggcctctacctcattcactggagcaccagccacctcaaccgc
ctcatcctcacggtggcccagcgtgaccaggcatctggcccgaagggcttgcgcctgcgg
aagttccccatagaggtacaggctgggaccatcacgctggagggctgggaccggcccttc
cccagtgtgcgggagctgcgggctgccctgcagggatgctccctgcgggccggcaacgac
tgtttttccctgcgccgctgctgcctgccccggccaggagagatctccaacctcatcatc
atgcgggggtctcaggccagcaccaggccactcaacctcagccacctcagcttccaccgc
gtccgccaggaagacatcacccagctgtcccacttgggccagggcacaaggaccaacgtg
tatgagggcctcttgcgagtggagggcggaggccccaaggaggacaaggcaggaggcagg
gaccctgcaacgcctgacgagggctgtgggcaggacctgcgagtggttctcaaggtgcta
gaccccggtcaccatgacatcgccctggccttctatgagacagccagcctcatgagccag
gtctcccacgtgcacctggtcttcgtgcacggcgtctatgtgcacggctccgagaacatc
atggtgacggagtatgtggagcatgggcccttggacgtgtggctgcggcgggagaggggc
cacgtgcctctggcctggaagttgacagtggcccagcagctggccagcgccctcagctac
ctggaagacaagagtctggttcatggcaacgtttgtggccggaacatcctgctggcacgg
ctggggcaggcggagggcaccagccccttcattaagctgagtgacccgggcgtgggcctg
agcgccctctccagggaggagcgagtagagcggatcccttggacagccccagagtgcctg
tctggtggagccaacagcttaagcaccgcggcagacaagtggggctttggagccaccctc
ctggagatttgctttgatggggaggcccctctgcagggccgtagcccctccgagaaagag
cgcttctaccaaaagcagcacaagctgccggagccctcgtgcccagagctggccacactc
accagccagtgcctgacttacgagccagcccagcggccatccttccgcaccatcctgcgt
gacctcactcagctgcagccccaaaatctctttgatgtcttgtctgtgaacccggacttg
cctgtgtcagatcccacggttttccacaagcgttatttgaaaaagatccgggatctgggc
gagggtcacttcgggaaggtcagcctatattgctatgacccgaccaacgatggcactggt
gagatggtggcggtgaaggcccttaaggcaggcagcggtcctcagctccgcacgggttgg
aggcgagagatcgacatcctgcgcacgctctaccacgagcacattgtcaagtacaagggc
tgctgcgaggaccaaggtgagaagtcggtgcagctcgtcatggagtacgtgcccctgggc
agcctccgagactacttgccccggcacagcgtcgggctagcccagctgctgctcttcgcc
cagcagatctgcgagggtatggcctacctgcacgcgcagcactatgtgcaccgagacctg
gctgcgcgcaacgtgctgctggacaacaacaggctggtcaagatcggggacttcggccta
gccaaggccgtgcccgacggccacgagtactactgcgtgcgcgaggatggggacagccca
gtgttctggtatgccccagagtgcctgaaggagtgtaagttctactatgcatccgacgtc
tggtcctttggggtcaccatgtatgagctgctgacctattgtgactccagccagagtccc
ccttcgaaattcattgagctcataggccacacccagggacagatgatggtgctgaggctc
actgagctgctggaacgaggggagaggctgccacagccagagaaatgtccctgtgagatc
tatctgctcatgaagaactgctggggaacagaggcctcatcccggccgaccttccagaac
ctcatacccatcctcaaaacggtccatgagaaataccgaagccaggccccctcagtattc
agtgtctgctga
DBGET
integrated database retrieval system
