Vicugna pacos (alpaca): 102529688 Help Entry 102529688         CDS       T08098                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism vpc  Vicugna pacos (alpaca) Pathway vpc04064   NF-kappa B signaling pathway vpc04066   HIF-1 signaling pathway vpc04145   Phagosome vpc04151   PI3K-Akt signaling pathway vpc04217   Necroptosis vpc04613   Neutrophil extracellular trap formation vpc04620   Toll-like receptor signaling pathway vpc04621   NOD-like receptor signaling pathway vpc04936   Alcoholic liver disease vpc05132   Salmonella infection vpc05133   Pertussis vpc05134   Legionellosis vpc05135   Yersinia infection vpc05140   Leishmaniasis vpc05142   Chagas disease vpc05144   Malaria vpc05145   Toxoplasmosis vpc05146   Amoebiasis vpc05152   Tuberculosis vpc05161   Hepatitis B vpc05162   Measles vpc05164   Influenza A vpc05170   Human immunodeficiency virus 1 infection vpc05171   Coronavirus disease - COVID-19 vpc05205   Proteoglycans in cancer vpc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer vpc05321   Inflammatory bowel disease vpc05323   Rheumatoid arthritis vpc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:vpc00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     102529688 (TLR4)    04066 HIF-1 signaling pathway     102529688 (TLR4)    04151 PI3K-Akt signaling pathway     102529688 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     102529688 (TLR4)   09143 Cell growth and death    04217 Necroptosis     102529688 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     102529688 (TLR4)    04620 Toll-like receptor signaling pathway     102529688 (TLR4)    04621 NOD-like receptor signaling pathway     102529688 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     102529688 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102529688 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102529688 (TLR4)    05161 Hepatitis B     102529688 (TLR4)    05171 Coronavirus disease - COVID-19     102529688 (TLR4)    05164 Influenza A     102529688 (TLR4)    05162 Measles     102529688 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     102529688 (TLR4)    05135 Yersinia infection     102529688 (TLR4)    05133 Pertussis     102529688 (TLR4)    05134 Legionellosis     102529688 (TLR4)    05152 Tuberculosis     102529688 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     102529688 (TLR4)    05144 Malaria     102529688 (TLR4)    05145 Toxoplasmosis     102529688 (TLR4)    05140 Leishmaniasis     102529688 (TLR4)    05142 Chagas disease     102529688 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     102529688 (TLR4)    05321 Inflammatory bowel disease     102529688 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102529688 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102529688 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:vpc04131]     102529688 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:vpc04054]     102529688 (TLR4)    04090 CD molecules [BR:vpc04090]     102529688 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:vpc00536]     102529688 (TLR4) Membrane trafficking [BR:vpc04131]  Endocytosis   Phagocytosis    Toll-like receptors     102529688 (TLR4) Pattern recognition receptors [BR:vpc04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    102529688 (TLR4) CD molecules [BR:vpc04090]  Proteins   102529688 (TLR4) Glycosaminoglycan binding proteins [BR:vpc00536]  Hyaluronan   Cell surface receptors    102529688 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 TIR_2 LRR_5 LRR_9 LRR_Zer-1 LRR_6 LRR_EndoS ThsB_TIR LRR_LRWD1 Pentapeptide_4 ANG-1 Motif Other DBs NCBI-GeneID:  102529688 NCBI-ProteinID:  XP_006211443 UniProt:  A0A6I9IIF1 LinkDB All DBs Position 4 AA seq 841 aa AA seqDB search MMPHTHLAAALMTAMAFLSCLRSESWEPCVQVVPNISYQCMELNLYKVPDNIPTSTKILD LSFNYLNHLGSHSFSSFPELQVLDLSRCEIQMIDDNAYQGLNHLATLILTGNPIQSLALR AFSGIPSLQKLVAVETNLASLEDFPIGHLKTLKELNVAHNLIHSFKLPKYFSNLPNLEYL DLSNNKIQNIYHGDLQVLHQMPLLNLSLDLSLNPLDFIEPGAFKEIKLNKLTMRSNFNSI DTMKTCIQGLAGLKINRLVLGEFKNERNLESFDKSVMEGLCNLTIEQFRIANIREFPEDV TDSFNCLANASMISLLSLYLENLEAIPEDFRWQHLELVNCKFERFPTLKLNSLKKFVFIH NTGMSTFVKTELPNLQFLALKGNDLSFKGCCSHTDFGTTKLKYLDLSFNDIITMNSNFMG LEQLEHLDLQHSTLKQANDFSIFLSLRNLHYLDISYTQTRIVFHGIFHGLVSLQTLKMAG NSFQNNLLPDIFTEVTNLTILDLSKCQLEQLSQRAFDPLTKLQVLNMSHNKLLSLDILPY EPLRSLQILDCSFNRIVASKEKELQHLPRSLAFLNLTQNDFACVCEHQHFLQWLKDQRQL LVEAEQMVCTQPLDMQDMPVLSFRNATCQISKMTISVSVLTVLLVSVAGVLVYKFYFHLM LLAGCKKYGKGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA ANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLL RQQVELYRLLSRNTYLEWEDTVLGRHIFWRRLRKALLEGKAWSPEGTADAESSQHEATTS A NT seq 2526 nt NT seq  +upstreamnt  +downstreamnt atgatgcctcacactcacctagctgcggctctgatgacagccatggcctttctctcctgc ctgagatccgagagctgggaaccctgtgtgcaggtggttcctaacattagttaccaatgc atggagctgaatctctacaaagtccctgacaacatccccacatcgaccaagatactggac ctcagctttaactacctgaatcatttaggcagccatagcttctccagcttcccagaactg caggtgctggatttatccagatgtgaaattcagatgattgacgataatgcgtatcagggg ctaaaccaccttgccaccttgatattgacgggaaaccctatccagagtttagccctgaga gccttttctggaataccgagtttacagaagctggttgctgtggagacaaacctagcatct ctagaggacttccccattggacatctcaaaactttgaaggagcttaatgtggctcacaat cttatacattcctttaagctacctaaatatttctctaacctgcctaacctggagtatttg gatctttctaataacaaaatccaaaatatttatcatggagacttgcaggttctacatcaa atgcccctactcaacctctctttggacttgtccctgaaccctttagacttcatcgaacca ggtgcctttaaagaaattaagctcaataaactgactatgagaagtaattttaatagtata gatacaatgaaaacttgtattcaaggtctggctggtttaaaaatcaataggttggttttg ggagaatttaaaaatgaaaggaacttggaaagttttgacaaatctgtcatggaaggactg tgcaatttgaccattgaacaattccggatagcaaacatcagagaattcccagaggatgtt actgactcatttaactgcttggcaaatgcttctatgatttctctgttgagtctgtattta gaaaatctagaagccattcctgaagatttcagatggcaacacttagaattagttaactgt aaatttgaacgatttcccacactgaagctcaactctctcaaaaagtttgttttcatacac aacacaggcatgagcacttttgttaaaactgagctaccgaaccttcagtttctagctctc aagggaaatgatttgagtttcaagggttgctgttctcacactgatttcgggacaaccaaa ctgaagtatttagatctgagcttcaatgatatcattaccatgaattcaaacttcatgggc ttagagcaactagaacatctggatctccagcattccactttgaaacaggccaatgatttt tctatcttcctatcactcagaaaccttcattaccttgatatttcttatacccagacccga attgtcttccatggcatctttcatggcctggtcagtctccaaaccttaaaaatggctggc aattcttttcagaacaacttgctgcctgatattttcacagaggtgactaacttaaccatc ttggacctctctaagtgccaactggaacagctatcccagcgggcatttgaccccctcact aaactgcaggtgctaaatatgagtcacaacaaactcttgtcattggatatacttccttat gaacctctccgctccctccagattctagactgcagtttcaatcgtattgtggcctccaag gagaaagaactacagcatttgccaaggagcctcgcttttttaaaccttactcagaatgac tttgcttgtgtttgtgaacaccagcatttcctgcagtggctcaaggaccagaggcagctc ctggtagaagctgaacaaatggtgtgtacacaacctttagacatgcaggatatgcccgtg ctgagtttcaggaatgccacctgtcagataagcaagatgaccattagtgtgtcggtcctc actgtacttctggtatctgtggcaggagtcctggtctacaagttctatttccacctgatg cttcttgctggctgcaaaaagtatggcaaaggtgaaaacatctatgatgcctttgttatc tactccagccaggacgaagactgggtgaggaatgaacttgtaaaaaacttggaggagggg gtgccgccctttcagctctgccttcactacagagactttattcctggtgtggccattgct gccaacatcatccaggaaggtttccacaaaagccggaaggttattgtggtggtgtcccag cacttcatccagagccgctggtgtatctttgagtatgagattgcccagacctggcagttt ctgagcagtcgtgccggcatcatcttcatcgtcctgcagaagttggagaagtccctgctg cggcagcaggtggagctgtatcgtcttctcagcaggaacacctacctggagtgggaggac actgtcctggggcggcacatcttctggagacggctcagaaaagccttgctggagggtaag gcatggagtccagaaggaacagcggatgcagagagcagccagcatgaagcgacaacctct gcctga

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