Vicugna pacos (alpaca): 102530120
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Entry
102530120 CDS
T08098
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00230
Purine metabolism
vpc00670
One carbon pool by folate
vpc01100
Metabolic pathways
vpc01523
Antifolate resistance
Module
vpc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102530120 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102530120 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102530120 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
vpc04147
]
102530120 (ATIC)
Enzymes [BR:
vpc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
102530120 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
102530120 (ATIC)
Exosome [BR:
vpc04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
102530120 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
102530120
NCBI-ProteinID:
XP_006210030
UniProt:
A0A6I9IGK2
LinkDB
All DBs
Position
5
AA seq
591 aa
AA seq
DB search
MSSVSALFSVSDKTGLVEFARNLASVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEML
GGRVKTLHPAVHAGILARSIPEDSADMARLDFNLIRVVVCNLYPFAKTVASPDVTVEEAV
EQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVSAEMQGSDSKDTSLETRRQLALKAFTH
TAQYDEAISEYFRKEYSKGISQMPLRYGMNPHQTPAQLYTLKPRLPITVLNGAPGFINLC
DALNAWQLVKELKETLGIPAAASFKHVSPAGAAVGIPLSEDEARVCMVHDLYKTLTPIST
AYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNGN
YCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLPESALRDLIVA
TIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTG
VKRAEISNAIDQYVTGTIGEGEDLVKWKALFEEVPELLTEAEKKDWVDKLNEVSISSDAF
FPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1776 nt
NT seq
+upstream
nt +downstream
nt
atgtcttctgtttcagccttgtttagtgtctctgacaaaaccggccttgttgaatttgcc
aggaacttagcttctgttggtttgaatctgatcgcttctggagggactgcaaaagctctc
agagatgctggtctggcagtcagagatgtctctgagctaacaggatttcctgaaatgtta
ggggggcgtgtgaagaccttacatcctgcagtccatgctggaatcttggctcgcagtatc
ccagaagatagtgctgacatggccagacttgatttcaatcttataagagttgtcgtttgt
aatctgtatccctttgcgaagacagtggcttctccagatgtaactgttgaagaggctgtg
gagcaaattgacattggtggagtgaccctgctgagagcggcagccaaaaaccacgctcga
gtgacagtagtgtgtgaaccggaggactacgtggccgtgtccgcagagatgcagggctcc
gacagcaaggacacatctttggagacgagacgccagttagccttaaaggctttcacgcat
acggcacaatatgatgaagcaatttcagagtacttcaggaaagagtatagtaaaggaata
tctcagatgcccttgagatatggaatgaaccctcatcaaacccctgcccagttatacacg
ctgaagcccaggcttcccatcacagttctaaatggagcccctggttttataaacttgtgt
gatgctttgaatgcctggcagctggtaaaggaactcaaagaaactttaggcattccagct
gccgcctctttcaaacacgtcagcccagcaggcgctgctgttggaattccactcagtgaa
gatgaagccagagtctgcatggtccatgatctgtacaaaaccctcacacccatatccact
gcatatgcaagagcaagaggggccgataggatgtcttcctttggtgactttgttgcgtta
tctgatgtttgtgatgtccctactgccaaaattatctcccgggaggtgtctgatggtatt
gttgccccgggatatgaagacgaagctttgaaaatactttctaaaaagaaaaatgggaac
tactgtgttcttcagatggaccaatcttacaaaccagatgaaaatgaagttcgaactctc
tttggtcttcgtttaagccagaagagaaataatggtgtcatcgacaggtcattatttagc
aacgttgttaccaagaataaggatttgccggaatctgcgctcagagacctcattgtagcc
accattgctgtcaagtatactcagtctaactctgtgtgctatgccaagaacgggcaggtt
attggcatcggagcaggacagcagtctcggatacactgcacccgccttgcaggggataag
gcaaactattggtggcttaggcatcacccacaagtgctgtcaatgaagtttaaaactgga
gtgaagagagcagaaatctccaatgccattgatcaatacgtaactgggaccatcggcgag
ggtgaagatttggtgaagtggaaggcactgtttgaggaggtccctgagttattaactgag
gcagagaagaaggactgggttgacaaacttaatgaagtttccatcagctctgatgctttc
tttcctttcagggacaatgtagacagagccaagaggagtggcgtggcctacatcgctgct
ccgtccggttccgccgccgacaaggtcgtgattgaggcttgcgatgagctgggaataatc
ctcgctcacacgaaccttcggctgttccatcactga
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