KEGG   Vicugna pacos (alpaca): 102531272
Entry
102531272         CDS       T08098                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X3
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc04010  MAPK signaling pathway
vpc04014  Ras signaling pathway
vpc04015  Rap1 signaling pathway
vpc04020  Calcium signaling pathway
vpc04151  PI3K-Akt signaling pathway
vpc04520  Adherens junction
vpc04550  Signaling pathways regulating pluripotency of stem cells
vpc04714  Thermogenesis
vpc04810  Regulation of actin cytoskeleton
vpc04928  Parathyroid hormone synthesis, secretion and action
vpc05200  Pathways in cancer
vpc05205  Proteoglycans in cancer
vpc05215  Prostate cancer
vpc05218  Melanoma
vpc05224  Breast cancer
vpc05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102531272 (FGFR1)
   04014 Ras signaling pathway
    102531272 (FGFR1)
   04015 Rap1 signaling pathway
    102531272 (FGFR1)
   04020 Calcium signaling pathway
    102531272 (FGFR1)
   04151 PI3K-Akt signaling pathway
    102531272 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102531272 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    102531272 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102531272 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    102531272 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    102531272 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102531272 (FGFR1)
   05205 Proteoglycans in cancer
    102531272 (FGFR1)
   05230 Central carbon metabolism in cancer
    102531272 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    102531272 (FGFR1)
   05215 Prostate cancer
    102531272 (FGFR1)
   05224 Breast cancer
    102531272 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vpc01001]
    102531272 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:vpc04090]
    102531272 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:vpc00536]
    102531272 (FGFR1)
Enzymes [BR:vpc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102531272 (FGFR1)
Protein kinases [BR:vpc01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   102531272 (FGFR1)
CD molecules [BR:vpc04090]
 Proteins
  102531272 (FGFR1)
Glycosaminoglycan binding proteins [BR:vpc00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   102531272 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set ig Ig_3 Ig_2 V-set C2-set_2 Ig_4 ABC1 V-set_CD47 Pkinase_fungal DUF1615 zf-CCCH_9
Other DBs
NCBI-GeneID: 102531272
NCBI-ProteinID: XP_006201180
UniProt: A0A6I9I2Z3
LinkDB
Position
26
AA seq 820 aa
MWSWKCLLLWAVLVTATLCTARPAPTLPEQAQPWGAPVEVESLLVHPGDLLQLRCRLRDD
VQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSD
ALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGK
PLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHK
NIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVS
CAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRL
PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKP
SNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPD
TRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
NT seq 2463 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgcctcctcctctgggctgtgctggtcacagccacgctctgcacg
gccaggccggccccgaccttgcctgaacaagcccagccctggggagcccccgtggaagtg
gagtccctcctggtccaccccggtgacctgctgcagctccgctgtcggctgcgggacgat
gtgcagagcatcaactggctgcgggacggggtgcagctggtggaaagcaaccgcacccgc
atcacaggggaggaggtggaggtgcgggactccgtgcccgccgactccggcctctacgcc
tgtgtgaccagcagcccctcgggcagcgacaccacctacttctccgtcaacgtctcagat
gccctcccctcctcggaggacgacgatgacgatgatgactcctcttcagaggagaaagag
acggataacaccaaaccaaaccgtatgcccgtggctccctactggacgtccccagaaaag
atggaaaagaaattgcacgcagtgccagctgccaagacagtgaagttcaaatgcccctcc
agtgggactcccaaccccaccctgcgctggctgaaaaatggcaaggaattcaaacctgac
cacaggatcggaggctacaaggtccgttatgccacctggagcatcataatggattcagtg
gtgccttcagataaaggcaactacacctgcatcgtggagaacgaatacggtagcatcaac
cacacctaccagctggacgtcgtggagcggtcccctcaccggcccatccttcaggcaggc
ttgcccgccaacaagacagtggccctgggcagcaacgtggagtttatgtgtaaggtgtac
agtgacccacagccccacatccagtggctgaagcacatcgaggtgaacgggagtaagatt
ggtccagacaacctgccttatgtccagatcttgaagactgccggagttaataccaccgac
aaagagatggaggtgcttcacttaaggaatgtctcctttgaggacgcgggggagtataca
tgcttggcgggtaactctatcggactctcccatcactctgcatggttgaccgttctggaa
gccctggaagagcgaccagcggtgatgacctcgcccctgtacctggagatcatcatctac
tgcacaggggccttcctcatctcctgcatggtggggtctgtcatcatctacaagatgaag
agcggcaccaaaaagagtgacttccacagccagatggccgtgcacaagctggccaagagc
atccctctgcgcagacaggtgtcggctgactccagcgcgtccatgaactcaggagtcctg
ctggttcggccctcccggctctcctccagtggaacccccatgctggctggggtctctgaa
tacgagcttcccgaagaccctcgctgggagctccctcgagacagactggttttaggcaaa
cccctgggagagggctgctttgggcaggtggtgttggccgaggccattgggctggacaag
gacaaacccaaccgtgtgaccaaagtggctgtgaagatgctgaagtcggatgcaacagag
aaagacttgtcagacctgatctccgagatggagatgatgaagatgatcgggaaacacaag
aacatcatcaacctgctgggggcctgcacgcaggacggtcctctctatgtcatcgtggag
tacgcctccaagggcaacctccgggagtacctgcaggcccggaggccgcccgggctggaa
tactgctacaaccccagccacaacccggaggagcagctctcctccaaggacctggtatcc
tgcgcctaccaggtggcccgaggcatggagtatctcgcctccaagaagtgcatacaccga
gacctggccgccaggaacgtcctggtgacagaggataacgtgatgaagattgcagacttt
ggcctcgctcgcgacatccaccacatcgactactataaaaagacgaccaacggccggctg
cctgtgaagtggatggcgcccgaggcattgtttgaccggatctacacccaccagagtgat
gtgtggtcttttggggtgctcctatgggagatcttcactctgggcggctccccgtatcct
ggtgtacctgtggaggagcttttcaagctgctgaaagagggtcatcgtatggacaagccc
agtaactgcaccaatgagctgtacatgatgatgcgagactgttggcatgcagtcccctca
caaagacctaccttcaagcagctggtggaagacctggaccgcatcgtggccttgacctcc
aaccaggagtatctggacctgtcgatgcccctggaccaatactcccccagcttccccgac
acccgcagctccacctgctcctccggagaggattccgtcttctctcatgagcccttgccc
gaggagccctgcctgccccgacacccggcccagcttgccaatggcggactcaaacggcgc
tga

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