Vicugna pacos (alpaca): 102532821
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Entry
102532821 CDS
T08098
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04020
Calcium signaling pathway
vpc04022
cGMP-PKG signaling pathway
vpc04024
cAMP signaling pathway
vpc04148
Efferocytosis
vpc04260
Cardiac muscle contraction
vpc04261
Adrenergic signaling in cardiomyocytes
vpc04380
Osteoclast differentiation
vpc04919
Thyroid hormone signaling pathway
vpc04972
Pancreatic secretion
vpc05010
Alzheimer disease
vpc05017
Spinocerebellar ataxia
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05410
Hypertrophic cardiomyopathy
vpc05412
Arrhythmogenic right ventricular cardiomyopathy
vpc05414
Dilated cardiomyopathy
vpc05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
102532821 (ATP2A1)
04024 cAMP signaling pathway
102532821 (ATP2A1)
04022 cGMP-PKG signaling pathway
102532821 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102532821 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102532821 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
102532821 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
102532821 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
102532821 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
102532821 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102532821 (ATP2A1)
05017 Spinocerebellar ataxia
102532821 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
102532821 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102532821 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
102532821 (ATP2A1)
05414 Dilated cardiomyopathy
102532821 (ATP2A1)
05415 Diabetic cardiomyopathy
102532821 (ATP2A1)
Enzymes [BR:
vpc01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
102532821 (ATP2A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
102532821
NCBI-ProteinID:
XP_006201301
UniProt:
A0ABM5BRD5
LinkDB
All DBs
Position
18
AA seq
1000 aa
AA seq
DB search
MEAAHAKTTEECLAYFGVSETTGLTPDQVKRQLEKYGHNELPAEEGKSLWELVLEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSALDFNETKGVYEKVGEATETALTTLVEKMNVFNTDVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KEKILSVIKEWGTGRDTLRCLALATRDTPPKREDMVLDDSSRFMEYEMDMTFVGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDL
PLAEQREACHRACCFARVEPSHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYADDGPHVTYSQLTHFMKCGEDNPDFEGVDCEVFEAPQPMTMAL
SVLVTIEMCNALNSLSENQSLVRMPPWVNIWLVGSIGLSMSLHFLILYVDPLPMIFKLQA
LDLPHWLMVFKISLPVIGLDEILKFVARNYLEDPEDERRK
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacacgccaagaccacagaagaatgtttggcctattttggggtgagcgag
actacaggcctcaccccggaccaagttaagcggcaactggagaaatacggccacaatgag
ctccctgctgaggaagggaagtccctgtgggagttggtgttagagcagtttgaagacctc
ctggtgcggatccttctcctggccgcctgcatttcctttgtgttggcctggtttgaagaa
ggcgaagagactgtcactgcttttgttgaaccctttgtcatcctcttgatcctcattgcc
aatgccatcgtgggagtttggcaggagcgtaatgcagagaatgccatcgaggctctgaag
gaatatgaacccgaaatgggaaaagtctaccgggctgaccgcaagtcagtgcaaaggatc
aaggcccgggacattgtccccggagacattgtggaggtggctgtgggagacaaagtccct
gcagatatccgcatccttgccatcaagtccaccaccctccgggtcgaccaatccatcctg
acaggcgagtctgtctctgtcatcaagcacacagagcctgttcccgatcccagagctgtc
aaccaggataagaagaacatgcttttctcgggcaccaacattgctgctggcaaggcctta
ggcatcgtggccaccactggtgtgagcaccgagattgggaagatccgtgaccaaatggcc
gcaacagagcaggacaagaccccgttgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgcgtggccgtctggctcatcaacattggccacttcaat
gatcctgtccacgggggctcctggatccgtggtgccatctactactttaagattgccgtg
gctctggctgtggctgccatcccagaaggccttcctgccgtcatcactacctgcctggcc
ttgggcacccgccggatggccaagaaaaacgcaatcgtgaggagcttgccctccgtagag
actctgggctgcacctctgtcatctgttccgacaagacaggcaccctcaccaccaaccag
atgtctgtctgcaagatgtttatcatcgacaaagtggatggggacatctgccttctgaac
gagttctctatcactggttccacttatgctccagaaggagaggtcttgaagaatgataag
ccagtccgggcagggcagtatgatgggctggtggagctggccaccatttgtgccctctgc
aatgactccgccttggactttaatgagaccaaaggtgtttatgagaaggtgggtgaggcc
accgagacagcactcaccaccctggtggagaagatgaatgtattcaacacagacgtgaga
aacctctccaaggtggagagggctaacgcctgcaactcggtgatccgccagctaatgaag
aaggaattcaccctggagttctcccgggacagaaagtctatgtctgtctattgctctcca
gccaaatcccgggctgccgtgggcaacaagatgtttgtcaagggtgcccctgagggggtc
atcgaccgctgtaactatgtgcgagttggcaccactcgggtgccaatgacagggccggtg
aaggagaagattctgtcagtgatcaaggagtggggcactggccgggacaccttgcgctgc
ctggccctggccacccgggacacccccccaaagcgagaggatatggtcctggatgactct
tccaggttcatggagtacgagatggacatgacattcgttggcgtagtgggcatgctggac
ccgccccgcaaggaggtcacgggctctatccagctgtgccgtgatgctggcatccgggtg
atcatgatcactggggacaacaagggcacagccattgccatctgccgacgaattggcatc
tttggggagaatgaggaggtggccgaccgagcctacactggccgggagttcgatgacctg
cccctggccgagcagcgggaggcctgccatcgcgcctgctgcttcgcccgtgtggaaccc
tcccacaagtcaaagatcgtggagtatctgcagtccttcgatgagatcacagcaatgaca
ggtgatggtgtcaatgatgcccctgccctgaagaaggctgagattggcattgccatggga
tctggcactgctgtggccaagacggcctcagagatggtgctggccgatgacaacttctcc
accatcgtggctgccgtggaggagggccgcgccatctacaacaacatgaagcagtttatt
cgctacctcatctcctccaacgtgggcgaggtggtctgcatcttcctgacagccgccctg
gggctgcctgaggccctgatccctgtgcagctgctgtgggtgaacttggtgacggacggc
ctcccggccacagccctgggcttcaaccccccagacctggacatcatggaccggccgccc
cggagtcccaaggagcccctcatcagtggctggctcttcttccgctacatggcaattggg
ggctatgtgggtgcagccaccgtgggagcagcggcctggtggttcctgtatgctgatgat
ggacctcatgtcacctacagccagctgactcactttatgaagtgtggggaggacaacccc
gactttgagggtgtggattgtgaagtctttgaggccccccagcccatgaccatggccttg
tctgtgctggttaccatcgagatgtgcaatgctctcaacagcctgtctgagaaccagtcc
ctcgtgcggatgccgccctgggtgaacatctggctggtgggctccattggcctctccatg
tccctccacttcctcatcctctacgtggaccccctgccgatgatcttcaagctccaggcc
ctggacctgccccactggctcatggtcttcaagatctcattaccagtcatcgggcttgac
gaaatcctcaagttcgttgctcggaactacctggaggatccagaagatgaaagaaggaag
taa
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