Vicugna pacos (alpaca): 102532981
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Entry
102532981 CDS
T08098
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04066
HIF-1 signaling pathway
vpc04137
Mitophagy - animal
vpc04140
Autophagy - animal
vpc04148
Efferocytosis
vpc04659
Th17 cell differentiation
vpc04919
Thyroid hormone signaling pathway
vpc05167
Kaposi sarcoma-associated herpesvirus infection
vpc05200
Pathways in cancer
vpc05205
Proteoglycans in cancer
vpc05208
Chemical carcinogenesis - reactive oxygen species
vpc05211
Renal cell carcinoma
vpc05230
Central carbon metabolism in cancer
vpc05231
Choline metabolism in cancer
vpc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102532981 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102532981 (HIF1A)
04137 Mitophagy - animal
102532981 (HIF1A)
04148 Efferocytosis
102532981 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
102532981 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102532981 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102532981 (HIF1A)
05205 Proteoglycans in cancer
102532981 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
102532981 (HIF1A)
05230 Central carbon metabolism in cancer
102532981 (HIF1A)
05231 Choline metabolism in cancer
102532981 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102532981 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
102532981 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
102532981 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
vpc03000
]
102532981 (HIF1A)
Transcription factors [BR:
vpc03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
102532981 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
bHLH_HIF1A
Motif
Other DBs
NCBI-GeneID:
102532981
NCBI-ProteinID:
XP_015105262
UniProt:
A0A6J0AXN3
LinkDB
All DBs
Position
6
AA seq
764 aa
AA seq
DB search
MRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTEC
VLKPVESSDMKMTQLFTKVETEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTE
ADDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPSSETPKPLRSSADPALNQEVALKLE
PNPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKL
FAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSASTVTVF
QPTQMQEPPVTTTSTTATTDELKTVTKDGMEDIKILIAFPSPPHVPKETACATTSTYSDT
GSRTSSPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTTPEEELNPKILALQNAQRKRKI
EHDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRL
LGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atgaggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggat
attgaagatgaaatgaaggcacagatgaactgcttttatttgaaagccttggatggtttt
gttatggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatac
atgggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccgtgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaa
gagcaaaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccggggg
agaactatgaacataaaatccgcaacatggaaagtacttcactgcacaggccatattcat
gtgtacgataccaacagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgc
ttggtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagc
aagacttttctcagtcgtcacagcctggatatgaaattttcttattgtgatgaaagaatt
actgaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattat
catgctttggactctgatcatctgaccaaaactcatcacgatatgtttactaaaggacaa
gtcaccacaggacagtacaggatgcttgccaaaagaggtggatacgtctgggttgaaact
caagcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaat
tacgttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgt
gtcctcaaaccagttgaatcgtcagatatgaaaatgactcagctattcaccaaagttgaa
acagaagatacaagtagcctctttgataaacttaagaaggaacctgatgctttaacttta
ctggccccagctgctggagacacaatcatatctttagattttggcagcaatgacacagaa
gctgatgaccaacaacttgaggaagttcccttgtataatgatgtaatgctcccctcatcc
aatgagaaattacagaatataaatttggcgatgtctccattaccttcctctgaaactcca
aagcctcttagaagtagtgctgaccctgcactcaatcaggaagttgcattaaagttagaa
ccaaatccagagtcactggaactttcttttaccatgccccagattcaagatcagccagct
agtccttctgatggaagcaccagacaaagttcacctgagcctaacagtcccagtgaatat
tgttttgatgtggatagtgatatggtcaatgaattcaagttggaattggtagagaaactt
tttgctgaagacacagaagcaaagaatccattttccactcaggacactgatttagacttg
gagatgttagctccttatatcccaatggatgatgacttccagttacgttccttcgatcag
ttgtcaccattggaaagcagttctacaagccctcaaagtgcgagcacagttacagtattc
cagccgactcaaatgcaagaacctcctgttaccaccacctctacaactgccaccactgat
gaattaaaaacagtgacaaaagatggtatggaagacattaaaatattgattgcatttcca
tctcctccccacgtacctaaagaaactgcttgtgccacaacatcaacatatagtgatact
ggaagtcggacatcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaag
tctcatccacgaagccctaatgtgttatctgtcgctttgagtcaaagaactaccactcct
gaggaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaata
gaacatgatggttcactttttcaagcagtaggaattggaacattattacagcaaccagat
gatcgtgcaactactacatcactttcttggaaacgtgtaaaaggatgcaaatctagtgaa
cagaatggaatggaacaaaagacaattattttaataccttctgatttagcatgtagactg
ctggggcaatcaatggatgagagtggattaccacagctgaccagttatgattgtgaagtt
aatgctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttg
gatcaagttaactga
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