Vicugna pacos (alpaca): 102533620
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Entry
102533620 CDS
T08098
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00260
Glycine, serine and threonine metabolism
vpc00630
Glyoxylate and dicarboxylate metabolism
vpc00670
One carbon pool by folate
vpc01100
Metabolic pathways
vpc01200
Carbon metabolism
vpc01230
Biosynthesis of amino acids
vpc01240
Biosynthesis of cofactors
vpc01523
Antifolate resistance
vpc04981
Folate transport and metabolism
Module
vpc_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102533620 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102533620 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102533620 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102533620 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102533620 (SHMT1)
Enzymes [BR:
vpc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102533620 (SHMT1)
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Paralog
GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
102533620
NCBI-ProteinID:
XP_006213885
UniProt:
A0A6J3B7T3
LinkDB
All DBs
Position
16
AA seq
484 aa
AA seq
DB search
MVTPVNGAPWDADLWSSHSKMLAQPLKDSDEEVYDIIRKESRRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQLYGLDPRCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGRETQYNLELLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRVYQRQLVANCRALAEALMGLGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFRK
VAQFIHKGIQLTLQIQDAVGGRATLKEFTEKLAGEEAHRRALGALRAEVESFASLFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggtgactccagtcaacggggccccctgggatgccgacctgtggtcctcgcacagcaag
atgctggcacagcccctgaaggacagcgacgaggaggtctacgacatcatcaggaaggag
agccgccggcagcgggtcgggctggagctgatcgcctcggagaacttcgccagccgagct
gtcctggaggccctgggttcttgcttaaataacaagtactcggagggttaccccggccag
aggtactacggcgggactgagttcatcgacgagctggaggtcctctgtcagaagcgagcg
ctgcagctctatgggctggacccccggtgctggggcgtcaacgtccagccctactcaggc
tcccccgcgaacttcgccgtgtacaccgcgctggtagagccccacggccgcatcatgggc
ctggacctgcctgacgggggccacctgacccatgggttcatgacggacaagaagaagatc
tccgccacgtccatctttttcgagtctatgccctacaaggtgaacccggacaccggctac
atcaactatgaccagctggaggagaacgcccgcctcttccacccgaagctgatcatcgca
ggaaccagctgctattcccggaacctggactacgcccggctgcggaagatcgcagacgac
aatggggcgtatctcatggccgacatggcgcacatcagcgggctggtggcggccggcgtg
gtgccctccccctttgagcactgccacgtggtgtccaccaccacacacaagaccctgagg
ggctgccgcgccggcatgatcttctacaggaaaggagtgcgcagcgtggatcccaagaca
ggcagagagactcagtacaacctggagctgctcatcaactccgctgtgttcccaggcctg
cagggtggcccccacaaccacgccatcgctggggtcgccgtggctctgaagcaggccatg
actccggaattcagagtctaccagcgccagttggtggccaactgcagggcgctggccgag
gctttgatgggactgggctacaaggtggtcacaggtggttctgacaaccatctgatcctc
gtggacctccgatccaaaggcacggatggcggcagggccgagaaggtgctggaagcctgt
tccatcgcttgcaacaagaacacctgcccaggtgacaaaagtgcactgcggcccagcggg
ctgcggctggggactcctgcgctgacgtcccggggacttttagaagaagatttccgaaaa
gtcgcccagtttattcacaaagggatacaactgaccctgcaaatccaggatgccgtggga
ggcagggccaccctgaaggagttcacggagaagctggcgggggaagaggcgcaccggcgg
gccctgggggctctccgggcagaggtggagagctttgcctccctctttcctctgcccggc
ctgcctgacttctag
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