Vicugna pacos (alpaca): 102535933
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Entry
102535933 CDS
T08098
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc01521
EGFR tyrosine kinase inhibitor resistance
vpc01522
Endocrine resistance
vpc04010
MAPK signaling pathway
vpc04014
Ras signaling pathway
vpc04015
Rap1 signaling pathway
vpc04066
HIF-1 signaling pathway
vpc04068
FoxO signaling pathway
vpc04081
Hormone signaling
vpc04114
Oocyte meiosis
vpc04140
Autophagy - animal
vpc04144
Endocytosis
vpc04150
mTOR signaling pathway
vpc04151
PI3K-Akt signaling pathway
vpc04152
AMPK signaling pathway
vpc04211
Longevity regulating pathway
vpc04213
Longevity regulating pathway - multiple species
vpc04510
Focal adhesion
vpc04520
Adherens junction
vpc04550
Signaling pathways regulating pluripotency of stem cells
vpc04730
Long-term depression
vpc04913
Ovarian steroidogenesis
vpc04914
Progesterone-mediated oocyte maturation
vpc05200
Pathways in cancer
vpc05202
Transcriptional misregulation in cancer
vpc05205
Proteoglycans in cancer
vpc05214
Glioma
vpc05215
Prostate cancer
vpc05218
Melanoma
vpc05224
Breast cancer
vpc05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102535933 (IGF1R)
04014 Ras signaling pathway
102535933 (IGF1R)
04015 Rap1 signaling pathway
102535933 (IGF1R)
04066 HIF-1 signaling pathway
102535933 (IGF1R)
04068 FoxO signaling pathway
102535933 (IGF1R)
04151 PI3K-Akt signaling pathway
102535933 (IGF1R)
04152 AMPK signaling pathway
102535933 (IGF1R)
04150 mTOR signaling pathway
102535933 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
102535933 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102535933 (IGF1R)
04140 Autophagy - animal
102535933 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
102535933 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102535933 (IGF1R)
04520 Adherens junction
102535933 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
102535933 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102535933 (IGF1R)
04914 Progesterone-mediated oocyte maturation
102535933 (IGF1R)
09156 Nervous system
04730 Long-term depression
102535933 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
102535933 (IGF1R)
04213 Longevity regulating pathway - multiple species
102535933 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102535933 (IGF1R)
05202 Transcriptional misregulation in cancer
102535933 (IGF1R)
05205 Proteoglycans in cancer
102535933 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102535933 (IGF1R)
05214 Glioma
102535933 (IGF1R)
05218 Melanoma
102535933 (IGF1R)
05215 Prostate cancer
102535933 (IGF1R)
05224 Breast cancer
102535933 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102535933 (IGF1R)
01522 Endocrine resistance
102535933 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102535933 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
vpc04090
]
102535933 (IGF1R)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102535933 (IGF1R)
Protein kinases [BR:
vpc01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
102535933 (IGF1R)
CD molecules [BR:
vpc04090
]
Proteins
102535933 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Furin-like
Recep_L_domain
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
102535933
NCBI-ProteinID:
XP_006211568
UniProt:
A0A6I9IIM2
LinkDB
All DBs
Position
27
AA seq
1246 aa
AA seq
DB search
MTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDL
CPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENHECCHPECLGSCSA
PDDDAACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHDG
ECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLL
INIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFY
VLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRN
NGERASCESDVLHFTSTTTSKNRIIVTWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQ
DACGSNSWNMVDVDLPPNKDIEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEI
LYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHN
YCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKV
FENFLHNAIFVPRPERKRREVMQVANTTTSSRSRNTTVVDTYNITDPEELETEYPFFESR
VDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWE
PRPENSIFLKWPEPENPNGLILMYEIKYGSLVEDQRECVSRQDYRKYGGAKLNRLNPGNY
TARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK
RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGV
VKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMEL
MTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVV
LWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLE
IISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRHS
GHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
3741 nt
NT seq
+upstream
nt +downstream
nt
atgaccaacctcaaggacatcgggctgtacaacctgaggaacatcacccggggggccatc
aggatcgagaagaacgccgacctctgctacctctccacggtggactggtccctgatcctg
gacgccgtgtccaacaactacatcgtggggaacaagcccccgaaggagtgtggggacctg
tgtccagggacgatggaggagaagccgttgtgtgagaagaccaccatcaacaatgagtac
aactaccgctgctggaccacgaaccgctgccagaaaatgtgcccgagcgcgtgcgggaag
cgggcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagcgcg
cccgacgatgacgcggcctgcgtggcctgccgccactactactacgccggcgtctgcgtg
cccagctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgacttc
tgcgccaacatccccagcgccgagagcagtgactccgagggcttcgtgatccacgacggc
gagtgcatgcaggagtgcccctcgggcttcatccgcaacggcactcagagcatgtactgc
atcccttgcgaaggcccttgccccaaagtctgtgaggaagaaaagaaaacaaagaccatt
gattcagtcacttctgctcaaatgctccaaggatgcaccatcttcaagggcaacctgctc
attaatatccgacgtggcaacaacatcgcttctgaactggagaacttcatggggctcatt
gaggtggtgacgggctacgtgaagatccgtcactcccacgccttggtctccttgtccttc
ctgaagaacctgcgccagatcctaggagaggagcagctcgaggggaattactccttctac
gtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgactatc
aaagctgggaaaatgtactttgctttcaatcccaaattgtgtgtctccgaaatttaccgc
atggaggaggtgaccggaactaaagggcgccagagcaaaggggacataaacaccaggaac
aacggagagagagcctcctgcgaaagcgatgtcctgcacttcacctccaccaccacctcg
aagaaccgcatcatcgtcacctggcaccggtaccggccgcctgactacagggacctcatc
agcttcaccgtctactacaaggaggcaccctttaaaaacgtcacggagtatgacgggcag
gatgcctgtggctccaacagctggaacatggtggatgtggacctccctcccaacaaggac
atcgagcctggcatcttactgcaggggctgaagccctggacgcagtatgctgtctacgtc
aaggccgtgaccctcaccatggtggagaacgaccacatccgtggggccaagagcgagatc
ttgtacattcgcaccaacgcttcagttccttccattcccctggatgttctctcagcatca
aactcctcttctcagctgatcgtgaagtggaaccctccctctctgcccaacggcaatctg
agttactacatcgtgcggtggcagcgccagcctcaggacagctacctttaccggcacaac
tactgctccaaagacaaaatccccatcaggaagtatgctgatggcaccatcgacgtcgag
gaggtgacggagaatcccaagaccgaagtgtgtggtggcgagaaagggccgtgctgcgct
tgccccaaaaccgaggccgagaagcaggccgagaaggaggaggccgagtaccgcaaggtc
ttcgagaattttctgcacaacgccatcttcgtgcccagacccgaaaggaagcggagagag
gtcatgcaggtcgccaacaccaccacgtccagccgaagcaggaacaccacggtggtggac
acctacaacatcacagacccagaagagctcgagacagagtaccctttctttgaaagcaga
gtggacaacaaggagagaaccgtaatctctaacctccggccttttactttgtaccgcatc
gacatccacagctgtaaccacgaggctgagaagctgggctgtagcgcctccaactttgtc
ttcgcgagaaccatgcctgcagaaggagcagatgacattcctggaccggtgacctgggag
ccaaggccggagaactccatctttttaaagtggccagaacctgagaatcccaatggattg
attctaatgtatgaaataaaatacggatcactcgtcgaggatcagcgggagtgtgtgtct
agacaggactacaggaagtatggaggggccaagctgaaccggctcaacccggggaactac
acggcccggatccaggccacctctctctctgggaatgggtcgtggacggatcctgtgttc
ttctacgtccaggccaaaacgacgtatgaaaatttcatccatctgatcatcgccctgcct
gtggccgtgctgttgattgtgggcgggttggttataatgttgtacgtcttccacaggaaa
agaaataacagcaggctggggaacggagtgctgtatgcttcggtgaacccggagtacttc
agtgcagccgatgtgtacgtgcctgacgagtgggaagtcgcccgggagaagatcaccatg
agccgagagctggggcagggctcattcggcatggtttacgagggcgttgccaagggtgtg
gtcaaagatgagcctgagaccagggtggccattaagacggtgaacgaggccgcgagcatg
cgcgagaggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgtcaccac
gtggtgcgcctgctgggcgtggtgtcgcagggccagccgacgctggtcatcatggagctc
atgacccggggggacctcaaaagttatctccggtctctgaggccagaaatggagaataac
ccagtcctagcacctccaagcctaagcaaaatgatccagatggctggagagattgcagac
ggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcccggaactgc
atggtggccgaagatttcacagtcaaaatcggagattttgggatgacgagagacatctat
gagacagactattaccggaaaggagggaaagggctgctgcccgtgcgctggatgtccccc
gagtccctcaaggatggagtcttcaccacgcactccgatgtctggtccttcggggtcgtc
ctctgggagattgccacgctggccgagcagccgtaccagggcttgtccaacgagcaagtc
cttcgcttcgtcatggagggtggccttctggacaagccggacaactgtcctgacatgctg
tttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccctccttcctggag
atcatcagcagcatcaaggatgagatggagcccggcttccgggaggtgtccttctactac
agcgaggagaacaagccgcccgaacccgaggagctggacctggagccggagaacatggag
agcgtccccctggacccctcggcctcctcgtcctccctgccgctgcccgacagacactca
ggacacaaggccgagaacggccccggccccggcgtgctggtcctgcgagccagcttcgac
gagagacagccttacgcgcacatgaacgggggccgcaagaacgagcgggccctgcctctg
ccccagtcttcgacctgctga
DBGET
integrated database retrieval system
