Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:vpc00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
102536001 (HMBS)
Enzymes [BR:vpc01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.61 hydroxymethylbilane synthase
102536001 (HMBS)
361 aa
MSGNGNAAAKAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKALYPGLQFEIIAMSTTG
DKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRETPY
DAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFKSIRGNLNTRLRKLDEL
QEFSAIILAAAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVCVLHD
PETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSMQETMQATIH
VPAQHEDGPDDDPQLVGITARNIPREAQLAAENLGVSLATLLLNKGAKNILDVARQLNDA
H
