Vicugna pacos (alpaca): 102537306
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Entry
102537306 CDS
T08098
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04020
Calcium signaling pathway
vpc04022
cGMP-PKG signaling pathway
vpc04024
cAMP signaling pathway
vpc04148
Efferocytosis
vpc04260
Cardiac muscle contraction
vpc04261
Adrenergic signaling in cardiomyocytes
vpc04380
Osteoclast differentiation
vpc04919
Thyroid hormone signaling pathway
vpc04972
Pancreatic secretion
vpc05010
Alzheimer disease
vpc05017
Spinocerebellar ataxia
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05410
Hypertrophic cardiomyopathy
vpc05412
Arrhythmogenic right ventricular cardiomyopathy
vpc05414
Dilated cardiomyopathy
vpc05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
102537306 (ATP2A2)
04024 cAMP signaling pathway
102537306 (ATP2A2)
04022 cGMP-PKG signaling pathway
102537306 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102537306 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102537306 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
102537306 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
102537306 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
102537306 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
102537306 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102537306 (ATP2A2)
05017 Spinocerebellar ataxia
102537306 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
102537306 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102537306 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
102537306 (ATP2A2)
05414 Dilated cardiomyopathy
102537306 (ATP2A2)
05415 Diabetic cardiomyopathy
102537306 (ATP2A2)
Enzymes [BR:
vpc01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
102537306 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
102537306
NCBI-ProteinID:
XP_006204921
UniProt:
A0A6I9I6V0
LinkDB
All DBs
Position
32
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKLVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKIPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTTKAFTGREFDEL
NPSAQREACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacaggactgagcctggagcaggtcaagaagctcaaggagaaatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtaattgagcagtttgaagactta
ctagttagaattttattgttggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccttttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgcaatcgaagcccttaag
gagtatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagtcgaccagtcaattctt
acaggtgaatctgtctctgtcatcaagcacactgaccctgtccctgacccacgggctgtc
aaccaggataagaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagttaacaccgaaattggcaagatccgagatgaaatggtg
gcgacggagcaggagagaacgcccctccagcagaaactagatgagtttggggaacagctt
tccaaagtcatctcccttatttgcattgcagtctggatcataaacattgggcactttaac
gacccagttcacggcggctcctggatcagaggtgctatttactactttaaaattgccgtg
gccctggctgtagcagccatccctgaaggtctgcctgctgtcatcaccacctgcctggct
ctcgggactcgcagaatggcaaagaaaaatgccattgttcgaagtctcccttctgtggaa
accctcggttgtacttctgttatctgctcagacaagactggtacgcttacaacaaaccag
atgtcagtctgtaggatgttcattctggacaaagttgaaggtgatacttgttcccttaat
gagttcaccataactggatcgacatacgcacctattggagaagtacataaagatgataaa
ctagtgaagtgtcatcagtatgatggtcttgtggaattggcaacaatctgtgctctctgt
aatgactctgctttggattataatgaggcgaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtatttgataccgaactgaaa
ggtctttctaaaatagaacgagccaatgcctgcaactcggtcattaaacagttgatgaaa
aaagaatttactctagagttttcacgggatagaaaatcaatgtcagtttattgtacacca
aacaaaccgagccggacatccatgagcaagatgtttgtgaagggtgctcctgaaggcgtc
attgacaggtgcactcacatccgcgtcgggagtacgaagatccccatgactccaggagtc
aagcagaagatcatgtctgtcatccgggagtggggcagcggcagtgacaccctgcgatgc
ctggccctggccactcacgacaaccccctgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatatgagaccaacctgacgttcgttggctgtgtgggcatgctggac
cctccgaggattgaagtggcctcctctgtgaagctgtgccggcaggcgggcatccgggtc
atcatgatcacaggcgacaacaagggcaccgccgtggccatctgccgccgcatcggcatc
tttgggcaggacgaggatgtgaccacgaaggctttcacgggtcgggagtttgatgagctc
aatccctccgcccagagagaagcctgcttgaacgcccgctgttttgctcgggttgaacct
tcccacaagtctaaaattgtagaatttctccagtcttttgatgagattacagccatgact
ggggacggtgtgaacgatgctcccgctctcaagaaatctgagattggcattgccatgggc
tctggcaccgcggtggctaaaactgcctctgagatggtcctggctgacgacaacttctcc
accatcgtggctgccgtggaggaggggcgggcgatatacaacaacatgaagcagttcatc
cgctacctcatctcgtccaacgtgggggaagttgtctgtattttcctgacagcagccctt
ggctttcctgaggcattaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccactgccctggggttcaaccctcctgatctggacattatgaacaaaccgccc
cggaaccccaaggaaccgctgatcagcgggtggctctttttccgctacctggctattggc
tgttatgttggcgctgctactgtgggggctgccgcgtggtggttcattgctgccgatggt
ggtccgagggtgaccttctaccagctgagtcatttcctacagtgtaaagaggacaacccg
gacttcgaaggagtggattgtgcaatctttgaatccccgtacccgatgacaatggcgctg
tctgttctagtcaccatagagatgtgtaatgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccttgggagaatatctggctcgtgggctccatctgcctgtccatg
tcactccacttcttaatcctctacgtggaacccttgccacttatcttccagatcacaccg
ctgaatgtgacccagtggctgatggtgctgaaaatctccttgcccgtgattctaatggac
gagaccctcaaatttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gctaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccctttgtgctg
cttataatgcccctggtgatctgggtctatagcacagacactaactttagtgacatgttc
tggtcttga
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