KEGG   Vicugna pacos (alpaca): 102537789
Entry
102537789         CDS       T08098                                 
Symbol
PLD2
Name
(RefSeq) phospholipase D2
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc00564  Glycerophospholipid metabolism
vpc00565  Ether lipid metabolism
vpc01100  Metabolic pathways
vpc04014  Ras signaling pathway
vpc04024  cAMP signaling pathway
vpc04071  Sphingolipid signaling pathway
vpc04072  Phospholipase D signaling pathway
vpc04144  Endocytosis
vpc04666  Fc gamma R-mediated phagocytosis
vpc04724  Glutamatergic synapse
vpc04912  GnRH signaling pathway
vpc04928  Parathyroid hormone synthesis, secretion and action
vpc05200  Pathways in cancer
vpc05208  Chemical carcinogenesis - reactive oxygen species
vpc05212  Pancreatic cancer
vpc05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    102537789 (PLD2)
   00565 Ether lipid metabolism
    102537789 (PLD2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102537789 (PLD2)
   04072 Phospholipase D signaling pathway
    102537789 (PLD2)
   04071 Sphingolipid signaling pathway
    102537789 (PLD2)
   04024 cAMP signaling pathway
    102537789 (PLD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102537789 (PLD2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    102537789 (PLD2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102537789 (PLD2)
   04928 Parathyroid hormone synthesis, secretion and action
    102537789 (PLD2)
  09156 Nervous system
   04724 Glutamatergic synapse
    102537789 (PLD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102537789 (PLD2)
   05208 Chemical carcinogenesis - reactive oxygen species
    102537789 (PLD2)
   05231 Choline metabolism in cancer
    102537789 (PLD2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102537789 (PLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vpc04131]
    102537789 (PLD2)
Enzymes [BR:vpc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     102537789 (PLD2)
Membrane trafficking [BR:vpc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102537789 (PLD2)
 Endosome - Golgi transport
  Others
   Others
    102537789 (PLD2)
SSDB
Motif
Pfam: PLDc PX PLDc_2 PH PH_2
Other DBs
NCBI-GeneID: 102537789
NCBI-ProteinID: XP_006217630
UniProt: A0A6J0B1P3
LinkDB
Position
Unknown
AA seq 933 aa
MAATPESLFPTGGDLDSSQLHMEPDEVDTLKEGEDPADRMHPFLAIYNLQPLKMHPLVFA
PGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLLRHKVL
MSLLPLARFAVAYAPAQEAANREMPSLPRAGPEGSARHASSKQKYLENYLNRLLTMSFYR
NYHAMTEFLEVSQLSFIPDLGCKGLEGVIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV
KDSFLMYMCLETGAISFVQLFDPGFEVQVGKRSTEAQYGVRIDTSHRSLILKCSSYRQAR
WWAQEITELAQGPGKDFIQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILQAQEEIF
ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL
MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGNSSE
SATPQPPTLCSDSLDTPDLSHNQLFWLGKDYSNLITKDWVHLDRPFEDFIDRETTPRMPW
RDIGVVIHGLPARDLARHFIQRWNFTKTTKAKYKIPLYPYLLPKSNSTANQLPFVLPGGQ
CATVQVLRSVDRWSAGTSENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNAIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWRNYMSICGLRTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTETEPSLMGGVEYQAGRFALSLRKHCFSVILGADARPNLDLQDPICD
DFFQLWQDTAESNANIYEQIFRCLPSNAIRSLRALREYVAVEPLATVSPPLAQSELTQVQ
GHLVHFPLKFLEDESLLPPLGSKEGVMPLEVWT
NT seq 2802 nt   +upstreamnt  +downstreamnt
atggcggcaacccctgagagccttttccccaccgggggtgacctggactccagccagtta
catatggagcccgatgaggtggacactctaaaggagggagaggacccagctgaccggatg
cacccctttctggccatctacaaccttcagcccctgaaaatgcaccccttggtgtttgcc
cctggggtccccgtcatagcccaggtggtgggcactgaaagatacaccagtggatccaag
gtgggaacgtgcactctgtattctgtccgcttgactcacggcgactttacctggacaacc
aagaagaagttccgtcatttccaggagctgcatcgggacctcctgagacacaaagtcttg
atgagtctgctccctctggctcgttttgccgttgcctacgctccagcccaagaggcagcc
aacagggagatgccctctctaccccgagcaggtcctgagggctccgccagacatgcatcc
agcaaacagaaatatctggaaaattacctcaaccgtctcctgaccatgtctttctaccgc
aactaccacgccatgacggagttcctggaagtcagtcagctatcctttatcccagacctt
ggatgcaaagggctggagggggtgatccggaagcgctcaggtggccaccgcgttcctggc
ctcacctgctgtggccgagaccaagtttgttatcgctggtccaagaggtggctggtggtg
aaggactccttcctgatgtacatgtgcctggagaccggcgccatctcatttgttcagctc
tttgaccctggcttcgaggtgcaggtggggaaaaggagcacagaggcacagtacggggtc
cggatcgacacctcccacaggtccctgattctgaagtgtagcagctaccggcaggcgcgg
tggtgggctcaggagatcaccgagctggcccagggccctggcaaggacttcatacagctg
caccggcatgacagctacgccccgccccggcctgggaccttggcccggtggtttgtgaat
ggggcaggttactttgctgctgtggcagatgccatcctgcaagctcaggaagagattttc
atcacagattggtggttgagtcctgaggtttacctgaagcgtccggcccattcagatgac
tggagactagacattatgctcaagaggaaggcggaggagggtgtccgggtgtccatcctg
ctgtttaaggaagtggagttggccttgggcatcaacagtggctacagcaagagggctctg
atgctgctgcaccccaacataaaggtgatgcgccacccagatcaggtgacactgtgggcc
catcatgagaagctcctggtggtagaccaagtagtggccttccttggggggctagacctc
gcctatggccgctgggatgacctgcactaccgactgactgaccttgggaactcctctgag
tcagctaccccccagcctcccaccctgtgctcagactccttggacaccccagacctctct
cacaaccagctcttctggctgggcaaggactacagcaatctcatcactaaggactgggtg
catctggatcggccttttgaggatttcattgatagggagaccacaccccggatgccatgg
cgggacatcggcgtggtcattcacggcctgcctgcccgggaccttgcccggcatttcatc
cagcgctggaacttcaccaagactaccaaggccaagtacaagatacccttgtacccctac
ctgctgcccaagtccaacagcactgcaaaccagctcccctttgtgctcccaggagggcag
tgcgccaccgtgcaggtcttacggtcagtggaccgctggtctgcggggacttcagagaac
tccatcctcaatgcctacctgcacaccatcagagagagccagcacttcctctacattgag
aatcagttcttcattagctgctcagatgggcggacagttctgaacaaggtgggcgatgag
attgtggacagaatcctgaaagcccacaaacaggggcagtgcttccgagtctacgtgctt
ttgcccctgctccccggatttgagggtgacatctccacaggtggtgggaatgccatccag
gccattctgcacttcacttacaggaccctctgtcgtggggaatattcgatcctgcatcgc
ctcaaagcagccatggggacagcgtggcggaactatatgtccatctgtgggcttcgcaca
catggagagctgggcgggcacccggtctcagagctcatctatatccacagcaagatgctc
attgcagatgaccggacagtcatcattggctctgccaacattaatgatcgaagcctgctg
gggaagcgggacagtgagctggccgtgctgatcgaggacacggagacggagccatccctc
atgggcggtgtggagtatcaagcgggcaggtttgccttgagtttgaggaagcactgcttc
agcgtgattcttggggcagatgcccggccgaacctagatctccaagacccgatctgtgat
gatttcttccagttgtggcaagacacagctgagagcaatgccaatatctatgagcagatc
ttccgctgcctgccgtccaacgccatacgctccctgcgggcactccgggagtatgtggcc
gtggagcccctagccacggtcagccctcccttggcccagtctgaactcacccaggtccag
ggccatctagtccacttccccctcaagttcctggaggatgagtctttgctgccccccctg
ggtagcaaggagggtgtgatgcccctagaagtgtggacatag

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