Vicugna pacos (alpaca): 102537861
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Entry
102537861 CDS
T08098
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04140
Autophagy - animal
vpc04141
Protein processing in endoplasmic reticulum
vpc04210
Apoptosis
vpc04932
Non-alcoholic fatty liver disease
vpc05010
Alzheimer disease
vpc05012
Parkinson disease
vpc05014
Amyotrophic lateral sclerosis
vpc05016
Huntington disease
vpc05017
Spinocerebellar ataxia
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102537861 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102537861 (ERN1)
09143 Cell growth and death
04210 Apoptosis
102537861 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102537861 (ERN1)
05012 Parkinson disease
102537861 (ERN1)
05014 Amyotrophic lateral sclerosis
102537861 (ERN1)
05016 Huntington disease
102537861 (ERN1)
05017 Spinocerebellar ataxia
102537861 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
102537861 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102537861 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102537861 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
vpc01001
]
102537861 (ERN1)
Enzymes [BR:
vpc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102537861 (ERN1)
Protein kinases [BR:
vpc01001
]
Serine/threonine kinases: Other
IRE family
102537861 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Motif
Other DBs
NCBI-GeneID:
102537861
NCBI-ProteinID:
XP_006199376
UniProt:
A0A6I9I0S9
LinkDB
All DBs
Position
16
AA seq
963 aa
AA seq
DB search
LLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPA
FLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLT
GEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAAALPEDDGD
YKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVMHINVAVETLRY
LTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGST
LPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSAS
TKMLERFPNNLPRHRENVIPADSEKKSFEEVIDLVDQTSENAPTTVSQDVEEKFVHAPAK
PEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQRQLQHQQLQKELEKIQLLQQQ
QLPFHPPGDAAPDIELLDLSGQYSESSGTSSPSTSPRASNHSLHSSGSTSKAGTGPFLEQ
DDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQ
LLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTS
GLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGT
EGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGAYSLDC
LQSEKHEDVIARELIEKMIAKDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESL
DGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYREL
PEEVRETLGSLPDDFVRYFTARFPHLLLHTYRAMELCCHERPFQPYYSLERPESRPPMTP
DAL
NT seq
2892 nt
NT seq
+upstream
nt +downstream
nt
ctgctgcctggccccgggatttttggaagccccagcactgtgacgcttcctgaaacctta
ctgtttgtgtcaaccctggatggaagtttgcatgctgtcagcaagaggacaggctccatc
aaatggactttaaaagaagatccagtcctgcaggttccaacacatgttgaagagcctgcc
ttcctcccagatcccaatgatggcagcctgtatacgctcgggggcaagaataatgaaggc
ctgacgaaacttccctttacgatcccggagttggtgcaggcatccccatgccgaagttca
gatggaatcctctacatgggtaaaaagcaggacatttggtatgttattgacctcctgact
ggggagaagcagcagactttgtcatcggcctttgcagatagtctgtgcccgtcaacctct
cttctgtaccttgggcgaacagagtacaccatcaccatgtacgacaccaagacccgcgag
ctgcggtggaacgccacctacttcgactacgcggccgcgctgcccgaggacgacggggac
tacaaaatgtcccactttgtgtccaatggcgatgggctggtggtaactgtggatagtgaa
tctggagacgtcctgtggatccagaactatgcttcccccgtggtggccttctacatctgg
cagcgggagggcctgcggaaggtgatgcacatcaatgttgctgtggagaccctgcgctac
ctgaccttcatgtccggggaggtggggcgcatcaccaagtggaagtatccattccccaag
gagacggaggccaagagcaagctgacgcccaccctgtacgttgggaagtactccaccagc
ctctatgcttccccctcaatggtacatgagggggtcgctgttgtgccccgaggcagcacc
cttcctctgctggaaggcccccagaccgacggtgtcaccatcggggacaagggggagtgt
gtgatcacgcccagcacggacctgaagttcgaccccgggctcaaagggaagagcaagctc
aactacctgaggaactactggctgctgataggacaccacgaaaccccactgtcagcatcc
accaagatgctggagagattccccaacaacctgcccagacaccgggagaacgtgattcct
gccgactccgagaaaaagagctttgaagaggttatcgacctggttgaccagacttcagaa
aacgcccctaccacggtttcccaggatgtggaagagaagttcgttcatgcacctgccaag
cccgaggcccccgtggactccatgctcaaggacatggccaccatcatcctgagcaccttc
ctgctcattggctgggtggccttcatcatcacctaccccctgagcatgcatcagcagcgg
cagctccagcaccagcagctccagaaggaactggagaaaatccagctcctgcagcagcag
cagctgcccttccacccacctggagacgcggctccggacatcgagctcctggacttatcc
ggccagtactctgagagctcgggcaccagcagccccagcacatccccccgagcctccaac
cactcgctccactccagcggctctacctccaaggctggtaccggccccttcctggagcag
gacgacgaggatgaggaaaccagcatggtgatggttgggaaaatctctttctgtccgaag
gatgtcctgggccacggagctgagggcacaattgtgtaccggggcatgtttgacaaccgc
gacgtggcagtcaagaggatcctccccgagtgtttcagttttgcagatcgtgaggtccag
ctgctgcgagaatctgacgagcacccgaacgtgatccgttacttctgcaccgagcgggac
cggcagttccagtacatcgccattgagctgtgtgccgccaccctgcaggagtacgttgag
cagaaggacttcgcccacctcggcctggagcccatcaccctgctgcagcagactacgtcg
ggcctggcacacctgcactccctcaacatcgttcacagagacctgaagccccacaacatc
ctcctctccatgcccaatgcacatggcaggatcaaggccatgatctccgacttcggcctc
tgcaagaagctggcagtgggcaggcacagcttcagccgccgttcaggggtgcccggtaca
gaaggctggatcgccccggagatgctgagcgaagactgcaaggaaaaccctacctacacg
gtggacatcttctctgcgggctgcgtcttttactatgtgatatctgagggcagccacccc
tttggcaagtccctgcagcggcaggccaacatcctcctgggcgcctacagcctcgactgc
ctgcagtccgagaagcacgaagacgtcatcgcccgggaactgatagagaagatgatcgcg
aaggatcctcagaagcgcccgtctgcgaagcacgtgctgaaacacccattcttctggagc
ctcgagaagcagctccagttcttccaggatgtgagtgaccgaatagagaaggagtccctg
gacggcccgatagtgaagcagctggagcggggcgggcgggccgtggtgaagatggactgg
agggagaacatcaccgtccccctgcagacagatctgcgtaaattcagaacctataaaggc
ggctccgtccgagacctcctccgggccatgagaaataagaagcaccactaccgggagctc
cccgaggaggtgcgggagacgctgggctccctccccgacgacttcgtgcgctacttcacc
gcccgcttcccccacctcctcttgcacacctaccgggccatggagctgtgctgccacgag
agacccttccagccttactactccctcgagcgcccggagtcccggccccccatgactcca
gacgccctctga
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