Vicugna pacos (alpaca): 102539274
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Entry
102539274 CDS
T08098
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc04010
MAPK signaling pathway
vpc04020
Calcium signaling pathway
vpc04022
cGMP-PKG signaling pathway
vpc04024
cAMP signaling pathway
vpc04218
Cellular senescence
vpc04260
Cardiac muscle contraction
vpc04261
Adrenergic signaling in cardiomyocytes
vpc04270
Vascular smooth muscle contraction
vpc04530
Tight junction
vpc04713
Circadian entrainment
vpc04723
Retrograde endocannabinoid signaling
vpc04724
Glutamatergic synapse
vpc04725
Cholinergic synapse
vpc04726
Serotonergic synapse
vpc04727
GABAergic synapse
vpc04728
Dopaminergic synapse
vpc04911
Insulin secretion
vpc04912
GnRH signaling pathway
vpc04921
Oxytocin signaling pathway
vpc04924
Renin secretion
vpc04925
Aldosterone synthesis and secretion
vpc04927
Cortisol synthesis and secretion
vpc04929
GnRH secretion
vpc04930
Type II diabetes mellitus
vpc04934
Cushing syndrome
vpc04935
Growth hormone synthesis, secretion and action
vpc04973
Carbohydrate digestion and absorption
vpc05010
Alzheimer disease
vpc05020
Prion disease
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05031
Amphetamine addiction
vpc05207
Chemical carcinogenesis - receptor activation
vpc05410
Hypertrophic cardiomyopathy
vpc05412
Arrhythmogenic right ventricular cardiomyopathy
vpc05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102539274 (CACNA1D)
04020 Calcium signaling pathway
102539274 (CACNA1D)
04024 cAMP signaling pathway
102539274 (CACNA1D)
04022 cGMP-PKG signaling pathway
102539274 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
102539274 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
102539274 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
102539274 (CACNA1D)
04929 GnRH secretion
102539274 (CACNA1D)
04912 GnRH signaling pathway
102539274 (CACNA1D)
04921 Oxytocin signaling pathway
102539274 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
102539274 (CACNA1D)
04924 Renin secretion
102539274 (CACNA1D)
04925 Aldosterone synthesis and secretion
102539274 (CACNA1D)
04927 Cortisol synthesis and secretion
102539274 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
102539274 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
102539274 (CACNA1D)
04270 Vascular smooth muscle contraction
102539274 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
102539274 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
102539274 (CACNA1D)
04727 GABAergic synapse
102539274 (CACNA1D)
04725 Cholinergic synapse
102539274 (CACNA1D)
04728 Dopaminergic synapse
102539274 (CACNA1D)
04726 Serotonergic synapse
102539274 (CACNA1D)
04723 Retrograde endocannabinoid signaling
102539274 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
102539274 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
102539274 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
102539274 (CACNA1D)
05020 Prion disease
102539274 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
102539274 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
102539274 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102539274 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
102539274 (CACNA1D)
05414 Dilated cardiomyopathy
102539274 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102539274 (CACNA1D)
04934 Cushing syndrome
102539274 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
vpc04040
]
102539274 (CACNA1D)
Ion channels [BR:
vpc04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
102539274 (CACNA1D)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
NCAPD3_N
Motif
Other DBs
NCBI-GeneID:
102539274
NCBI-ProteinID:
XP_031542275
LinkDB
All DBs
Position
17
AA seq
2160 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDVVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEETKRNTSMPTSETESVNTENVS
GEGENQGCCGSLWCWWRGRGAAQAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYRAIDSNGENVGP
IYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIVDVALSEADNSEESNRISI
TFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKV
AMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTC
GSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPE
AKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVR
TALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDY
FRKFKKRKEQGLVGKYPAKNSTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEE
EDVFKRNGALLGNHVNHVNSDRDSLQQTNTTHRPLHVQRPSVPPASDTEKPLFPPAGNSV
CHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEHVSENGHHSSHKHGREPQ
RRSSIKRSDSGDEQFPTICREDPEIHGYFRDPHCLGEQEYFGCEDCYEGDSSPTGSRQSY
GYGCGYYNRHPGSSLDFERPRGYHHPQGFSEDDDSPVCYDSRRSPRRRLLPPTPTSHRRS
SFNFECLRRQSSQEEVPPSPALPHRAALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSW
ATPPATPSYRDWTPCYTPLIQVERPEALDQVNGSLPSLHRSSWYTDEPAISYRTFTPASL
TVPSSFHSKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMES
AASTLLNGNVHPRANGDVGPVSHRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq
6483 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagccgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctccgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgtgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataat
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaaatcgggaggctttgacgtcaaagccctccgc
gcctttcgagtgttaagaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattgttt
gtaatcattatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgattcagatgttgtagctgaagaggacccagcaccatgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacggagtgtcggagtggctgggttggcccc
aatggaggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagggagaaggctaaagcccgggga
gacttccagaagctccgggagaagcagcagctggaagaggatctaaagggctacttggat
tggatcacccaagcagaggacattgaccctgagaatgaagaagaaggaggcgaggaaacc
aaacggaataccagcatgcccaccagtgagacagagtctgtgaatacggagaacgtgagc
ggggaaggcgagaaccaaggctgctgtgggagcctctggtgctggtggagaggaagaggc
gctgcgcaggccgggccctctggttgtcggcggtggggtcaagccatctcaaaatccaag
ctcagccgacgctggcgtcgctggaaccgcttcaatcgccgaagatgcagggctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagcctgactggttgacacagattcaagacattgctaacaaa
gtccttttggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcgtatttcgtgtctctttttaatcggtttgattgctttgtggtgtgtggtggaattacc
gaaaccatcttggtggaactggaaatcatgtctcccctgggcatctctgtgtttcgatgt
gtgcgcctcctgagaattttcaaagtgaccaggcactggacgtccctgagcaacttggtg
gcatccttgttaaactccatgaagtccatcgcttcgctgctgcttctgcttttcctcttc
atcatcatcttttccttgcttgggatgcagctgttcggcggcaagtttaatttcgacgaa
acgcaaaccaagaggagcacctttgataatttccctcaagcacttctaacggtgttccag
attctgacaggtgaagactggaatgctgtgatgtatgatggcatcatggcgtatgggggc
ccatcatcttcaggaatgatcgtctgcatctacttcatcatcctcttcatctgcggtaac
tatattctactgaatgtctttttggccattgctgtagacaacttggctgatgctgaaagc
ttgaacactgctcagaaggaggaagctgaagaaaaggaaaggaaaaagattgccagaaaa
gaaagcctggaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aacaaggttacaattgacgactaccgagaagaggatgaggacaaggacccctacccgcct
tgtgatgtgccagtaggtgaagaggaagaagaggaggaggaggatgagcctgaggttcca
gctggcccccgtcctcgcagaatctctgagttgaacatgaaagagaaaattgcccctatt
cccgaagggagcgctttcttcattcttagcaagaccaacccgatccgagtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatccttgtcttcatcatgctgagcagc
gctgccctggcggctgaggaccctatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctattgaagatgacaact
tttggagctttcctccacaaaggggctttctgcaggaactacttcaacttactggatatg
ctggttgttggggtgtctctggtgtcatttgggatccaatccagtgccatctctgttgtg
aagattctgagggtcttaagggtcctgaggccactcagggcaatcaacagagcaaaagga
cttaagcacgttgtccagtgcgtctttgtggccatccggacaattggcaacatcatgatc
gtcaccaccctgctccagttcatgttcgcctgcattggggttcagctgttcaagggaaag
ttctatcgctgtaccgacgaagccaaaagtaaccctgaagaatgcagggggctcttcatc
ctctacaaggatggagatgtggataaccctgtggtccgtgagaggatctggcagaacagt
gatttcaactttgacaacgtcctctcggccatgatggctctgttcacagtctccacgttt
gagggctggcccgcgttgctgtacagagccatcgactcgaacggagagaacgtcggcccc
atctacaactaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtagcg
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacttttcaggagcagggggag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagctcgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgtttaatgacgccatggacatcctg
aacatggtcttcactggggttttcactgtcgagatggttttgaaagtcattgcttttaaa
cccaaggggtactttagtgatgcctggaacacgtttgactccctcatcgtaatcggcagc
attgtagacgtggccctcagcgaagctgacaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcgcctggtgaagcttctcagcaggggggaaggc
atccggacattgctgtggactttcattaagtcattccaggcgctcccctatgtcgccctt
ctcatagccatgctgttcttcatctacgcggttatcggcatgcagatgtttgggaaagtt
gccatgagagataacaaccagatcaacaggaacaataatttccagacctttcctcaggca
gtgctgctgctcttcaggtgtgcgacgggggaggcctggcaggaaatcatgctggcctgc
ctaccggggaagctctgtgaccccgagtcggattacaaccccggcgaggagtacacgtgt
ggaagcaacttcgccatcgtctatttcatcagtttttacatgctctgtgcgtttctgatc
atcaacctgttcgtggctgtcatcatggacaattttgattatctgacccgggactggtct
attctggggcctcatcatttagatgaattcaaaagaatatggtccgaatacgaccctgaa
gcaaagggaaggatcaagcacctggacgtggtcactctgctccgccgaatccagcctccc
ctgggatttgggaaattgtgcccacacagagtagcctgtaagagactagttgccatgaac
atgccgctcaacagtgatgggacagtgatgtttaatgcaactctgtttgctttggttcga
acggctcttaaaatcaagacggaagggaacctggaacaagctaatgaagaactccgagct
gtgatcaagaaaatttggaagaaaaccagcatgaaacttcttgaccaagttgtccctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggactggtgggaaaataccccgcgaagaac
agcacaattgccctacaggcgggattaaggacactgcacgacattgggccagaaatccgg
cgtgctatatcatgtgatttgcaagatgacgagccagaggaaacaaaacgagaagaagaa
gaagatgtattcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gatagagattcccttcagcagaccaataccacccaccgtcccctgcatgtccaaaggcct
tcagttccacctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtg
tgtcataaccatcataaccataattccataggaaagcaagttcccagctcaacaaatgcc
aatctcaataatgccaatatgtccaaagctgcccctggaaagcggcccagcattgggaac
cttgagcatgtgtctgaaaatgggcatcattcctcccacaagcatggccgtgagcctcaa
agaaggtccagtattaaaaggtctgactcaggagatgagcagttcccaactatttgccgg
gaagatccagagatacacggctactttagggacccccactgcttgggggagcaggagtat
tttggctgcgaggactgctacgagggcgacagctcgccgaccgggagcaggcaaagctac
ggctacggctgcggctactacaaccgacacccaggcagcagcttggatttcgagcggccc
cgagggtaccatcacccgcaaggcttctcggaggatgatgactcgcctgtttgctacgat
tcccggaggtctccaaggagacgcctactacctcccactccaacatcccaccggaggtcc
tccttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccgccatccccc
gccctcccccaccgcgcggccctgcctctgcacctgatgcagcaacagatcatggcagtt
gctggcctagattccagtaaagcccagaagtactcgccgagccactccacccggtcgtgg
gccacccctccagcgaccccatcgtatcgggactggacgccatgctacacccccctgatc
caggtcgagcggccagaggccctggaccaggtcaacggcagcctgccgtccctgcaccgc
agctcgtggtacacggacgagcctgccatctcctatcggaccttcacaccagccagcctg
accgtccccagcagcttccacagcaaaaacagtgacaagcagaggagcgcagacagcttg
gtggaggcagtcctgatatctgaaggcttaggacgatatgcgagggacccaaaattcgtg
tcagcaacaaaacacgaaattgccgatgcctgtgacctgaccattgacgagatggagagt
gcggccagcaccctgctgaacgggaacgtgcatccccgggccaacggggacgtgggccct
gtctcacaccggcaggactatgagctccaggacttcgggccgggctacagcgacgaggag
ccagaccctgggagggacgaggaggacctggcagatgaaatgatttgcatcaccaccctg
taa
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integrated database retrieval system
