KEGG   Vicugna pacos (alpaca): 102539859
Entry
102539859         CDS       T08098                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc01522  Endocrine resistance
vpc04010  MAPK signaling pathway
vpc04012  ErbB signaling pathway
vpc04014  Ras signaling pathway
vpc04024  cAMP signaling pathway
vpc04068  FoxO signaling pathway
vpc04071  Sphingolipid signaling pathway
vpc04137  Mitophagy - animal
vpc04140  Autophagy - animal
vpc04141  Protein processing in endoplasmic reticulum
vpc04210  Apoptosis
vpc04215  Apoptosis - multiple species
vpc04217  Necroptosis
vpc04310  Wnt signaling pathway
vpc04380  Osteoclast differentiation
vpc04510  Focal adhesion
vpc04517  IgSF CAM signaling
vpc04530  Tight junction
vpc04620  Toll-like receptor signaling pathway
vpc04621  NOD-like receptor signaling pathway
vpc04622  RIG-I-like receptor signaling pathway
vpc04625  C-type lectin receptor signaling pathway
vpc04657  IL-17 signaling pathway
vpc04658  Th1 and Th2 cell differentiation
vpc04659  Th17 cell differentiation
vpc04660  T cell receptor signaling pathway
vpc04664  Fc epsilon RI signaling pathway
vpc04668  TNF signaling pathway
vpc04722  Neurotrophin signaling pathway
vpc04723  Retrograde endocannabinoid signaling
vpc04728  Dopaminergic synapse
vpc04750  Inflammatory mediator regulation of TRP channels
vpc04910  Insulin signaling pathway
vpc04912  GnRH signaling pathway
vpc04914  Progesterone-mediated oocyte maturation
vpc04917  Prolactin signaling pathway
vpc04920  Adipocytokine signaling pathway
vpc04926  Relaxin signaling pathway
vpc04930  Type II diabetes mellitus
vpc04931  Insulin resistance
vpc04932  Non-alcoholic fatty liver disease
vpc04933  AGE-RAGE signaling pathway in diabetic complications
vpc04935  Growth hormone synthesis, secretion and action
vpc04936  Alcoholic liver disease
vpc05010  Alzheimer disease
vpc05012  Parkinson disease
vpc05016  Huntington disease
vpc05017  Spinocerebellar ataxia
vpc05020  Prion disease
vpc05022  Pathways of neurodegeneration - multiple diseases
vpc05132  Salmonella infection
vpc05133  Pertussis
vpc05135  Yersinia infection
vpc05142  Chagas disease
vpc05145  Toxoplasmosis
vpc05152  Tuberculosis
vpc05161  Hepatitis B
vpc05162  Measles
vpc05166  Human T-cell leukemia virus 1 infection
vpc05167  Kaposi sarcoma-associated herpesvirus infection
vpc05169  Epstein-Barr virus infection
vpc05170  Human immunodeficiency virus 1 infection
vpc05171  Coronavirus disease - COVID-19
vpc05200  Pathways in cancer
vpc05208  Chemical carcinogenesis - reactive oxygen species
vpc05210  Colorectal cancer
vpc05212  Pancreatic cancer
vpc05231  Choline metabolism in cancer
vpc05415  Diabetic cardiomyopathy
vpc05417  Lipid and atherosclerosis
vpc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102539859 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102539859 (MAPK10)
   04012 ErbB signaling pathway
    102539859 (MAPK10)
   04014 Ras signaling pathway
    102539859 (MAPK10)
   04310 Wnt signaling pathway
    102539859 (MAPK10)
   04668 TNF signaling pathway
    102539859 (MAPK10)
   04068 FoxO signaling pathway
    102539859 (MAPK10)
   04071 Sphingolipid signaling pathway
    102539859 (MAPK10)
   04024 cAMP signaling pathway
    102539859 (MAPK10)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102539859 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102539859 (MAPK10)
   04137 Mitophagy - animal
    102539859 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    102539859 (MAPK10)
   04215 Apoptosis - multiple species
    102539859 (MAPK10)
   04217 Necroptosis
    102539859 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102539859 (MAPK10)
   04530 Tight junction
    102539859 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102539859 (MAPK10)
   04621 NOD-like receptor signaling pathway
    102539859 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    102539859 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    102539859 (MAPK10)
   04660 T cell receptor signaling pathway
    102539859 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    102539859 (MAPK10)
   04659 Th17 cell differentiation
    102539859 (MAPK10)
   04657 IL-17 signaling pathway
    102539859 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    102539859 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102539859 (MAPK10)
   04920 Adipocytokine signaling pathway
    102539859 (MAPK10)
   04912 GnRH signaling pathway
    102539859 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    102539859 (MAPK10)
   04917 Prolactin signaling pathway
    102539859 (MAPK10)
   04926 Relaxin signaling pathway
    102539859 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    102539859 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    102539859 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    102539859 (MAPK10)
   04722 Neurotrophin signaling pathway
    102539859 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102539859 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102539859 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102539859 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    102539859 (MAPK10)
   05231 Choline metabolism in cancer
    102539859 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102539859 (MAPK10)
   05212 Pancreatic cancer
    102539859 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102539859 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    102539859 (MAPK10)
   05161 Hepatitis B
    102539859 (MAPK10)
   05171 Coronavirus disease - COVID-19
    102539859 (MAPK10)
   05162 Measles
    102539859 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102539859 (MAPK10)
   05169 Epstein-Barr virus infection
    102539859 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102539859 (MAPK10)
   05135 Yersinia infection
    102539859 (MAPK10)
   05133 Pertussis
    102539859 (MAPK10)
   05152 Tuberculosis
    102539859 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102539859 (MAPK10)
   05142 Chagas disease
    102539859 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102539859 (MAPK10)
   05012 Parkinson disease
    102539859 (MAPK10)
   05016 Huntington disease
    102539859 (MAPK10)
   05017 Spinocerebellar ataxia
    102539859 (MAPK10)
   05020 Prion disease
    102539859 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    102539859 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102539859 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    102539859 (MAPK10)
   05415 Diabetic cardiomyopathy
    102539859 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102539859 (MAPK10)
   04936 Alcoholic liver disease
    102539859 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    102539859 (MAPK10)
   04931 Insulin resistance
    102539859 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102539859 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102539859 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vpc01001]
    102539859 (MAPK10)
Enzymes [BR:vpc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102539859 (MAPK10)
Protein kinases [BR:vpc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102539859 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 102539859
NCBI-ProteinID: XP_031544381
LinkDB
Position
2
AA seq 389 aa
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENASTHEHFKRKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQI
YDKQLDEREHTIEEWKELIYKEVMTSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVND
ISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1170 nt   +upstreamnt  +downstreamnt
atgagcctccatttcttgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaacctaaagcctattggctccggggctcagggaatagtttgtgct
gcatatgacgctgtccttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacacatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggag
ttagaccatgagcgaatgtcttacctgctgtaccaaatgttgtgtggcatcaagcacctt
cactctgctggaattattcacagggacttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctagactttggactggccaggacagcaggcacgagcttcatgatg
actccgtatgtggtgacacgttattacagggcccctgaggtcattctgggcatgggctac
aaggagaacgctagtactcatgagcactttaaaagaaaagccagccaagccagggacttg
ttgtcaaagatgctagtgattgacccagcgaagaggatatcagtggacgacgccttgcag
catccgtacatcaatgtctggtatgaccctgccgaagtggaggcgcccccacctcagata
tatgacaaacaattggatgaaagagaacacaccattgaagagtggaaagaacttatctac
aaggaagtaatgacttccgaagagaagactaagaacggtgttgtgaaaggacagccttct
ccttcaggtgcagcagtgaacagcagtgagagtctccctccatcctcgtctgtcaatgac
atctcctccatgtccaccgaccagaccctggcatctgacactgacagcagcctggaagct
tcggcaggacccctgggttgttgcaggtga

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