Vicugna pacos (alpaca): 102539863
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Entry
102539863 CDS
T08098
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial isoform X1
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00020
Citrate cycle (TCA cycle)
vpc00620
Pyruvate metabolism
vpc01100
Metabolic pathways
vpc01200
Carbon metabolism
vpc04934
Cushing syndrome
vpc05200
Pathways in cancer
vpc05211
Renal cell carcinoma
Module
vpc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
vpc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102539863 (FH)
00620 Pyruvate metabolism
102539863 (FH)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102539863 (FH)
09162 Cancer: specific types
05211 Renal cell carcinoma
102539863 (FH)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102539863 (FH)
Enzymes [BR:
vpc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
102539863 (FH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
102539863
NCBI-ProteinID:
XP_006198857
UniProt:
A0A6I9I090
LinkDB
All DBs
Position
23
AA seq
510 aa
AA seq
DB search
MDRALRLFARSRFLSRVPAAVPGPGPGPRGAAVFPLWTSNAARMASQNSFRIEYDTFGEL
KVPNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAI
MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDH
VNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLRDALDAKSKEFAQIIKIGRTHTQDAV
PLTLGQEFSGYVQQMKYAITRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVSAL
TGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE
NEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSA
RLLGDASVSFTENCVVGIQANTERIDKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS
TLKATAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atggaccgcgcgctccggctcttcgcgcgttcgcgttttctctcgcgggttccagccgcc
gtccccggccctggcccgggtccccgtggtgcggcagtcttcccgctctggacttcgaac
gccgctcgaatggcaagccaaaattcttttcggatagaatatgatacctttggtgagctc
aaggtcccaaatgataagtattatggcgcccagactgtgagatctacaatgaactttaag
attggaggtgtgacagaacgcatgccaatcccagttattaaagcttttggcatcttgaag
cgagcagctgctgaagtaaaccaggattatggtcttgatccaaagattgctaatgcaata
atgaaggcagcagatgaggtagctgaaggtaaattaaacgatcattttcctcttgtggtg
tggcagactggatcaggaacccagacaaatatgaatgtaaacgaagtcattagcaacaga
gcgattgaaatgctaggaggtgaacttggcagcaagaaacctgtgcatcccaacgatcat
gttaataaaagccagagctccaatgatacttttcccacagcaatgcacattgcagctgcc
atagaagttcacgaagtactgctgccaggactgcagaagctacgtgatgctctcgatgca
aaatccaaagagtttgcccagatcatcaaaattgggcgtactcatacacaggacgctgtt
ccacttactcttgggcaggaatttagtggttatgttcagcaaatgaaatatgcaataaca
agaataaaagctgccatgccgagaatctacgagctcgcagctgggggcactgctgtcggt
acgggtttaaatacaagaattggctttgcggaaaaggttgctgccaaagtgtctgcactc
acaggcttgccttttgtcacagctccaaataaatttgaagctctggctgctcatgatgct
ttggttgagctcagtggagccatgaacactactgcctgtagtctgatgaagatcgcaaat
gacattcgttttctgggttctggtcctcgctcaggtctgggagaactgattttgcctgaa
aatgaaccaggaagcagtatcatgccaggcaaggtgaaccccacccagtgtgaagcaatg
accatggttgcagcccaagtcatggggaatcacgtcgctgttactgttggaggcagcaat
ggacattttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcggcc
aggctactgggggatgcgtcggtttccttcacagaaaactgcgtggtgggaatccaggcc
aacacagaaaggatcgacaagctaatgaatgagtctctaatgttggtgacagctcttaat
cctcatatagggtatgacaaagcagccaagattgctaagaccgcacacaaaaatggatca
accttaaaggcaactgccattgaacttggctatctcacagcagagcaatttgatgagtgg
gtaaaacctaaggacatgttgggtccaaagtga
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