KEGG   Vicugna pacos (alpaca): 102541172
Entry
102541172         CDS       T08098                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc04010  MAPK signaling pathway
vpc04012  ErbB signaling pathway
vpc04620  Toll-like receptor signaling pathway
vpc04664  Fc epsilon RI signaling pathway
vpc04668  TNF signaling pathway
vpc04912  GnRH signaling pathway
vpc04926  Relaxin signaling pathway
vpc04935  Growth hormone synthesis, secretion and action
vpc04936  Alcoholic liver disease
vpc05132  Salmonella infection
vpc05135  Yersinia infection
vpc05142  Chagas disease
vpc05161  Hepatitis B
vpc05166  Human T-cell leukemia virus 1 infection
vpc05167  Kaposi sarcoma-associated herpesvirus infection
vpc05169  Epstein-Barr virus infection
vpc05208  Chemical carcinogenesis - reactive oxygen species
vpc05417  Lipid and atherosclerosis
vpc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102541172 (MAP2K4)
   04012 ErbB signaling pathway
    102541172 (MAP2K4)
   04668 TNF signaling pathway
    102541172 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102541172 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    102541172 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102541172 (MAP2K4)
   04926 Relaxin signaling pathway
    102541172 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    102541172 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    102541172 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102541172 (MAP2K4)
   05161 Hepatitis B
    102541172 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102541172 (MAP2K4)
   05169 Epstein-Barr virus infection
    102541172 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102541172 (MAP2K4)
   05135 Yersinia infection
    102541172 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102541172 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102541172 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    102541172 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102541172 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vpc01001]
    102541172 (MAP2K4)
Enzymes [BR:vpc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102541172 (MAP2K4)
Protein kinases [BR:vpc01001]
 Serine/threonine kinases: STE group
  STE7 family
   102541172 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 102541172
NCBI-ProteinID: XP_031530676
UniProt: A0A6J3AD94
LinkDB
Position
Unknown
AA seq 408 aa
MAAPSPSGGGGSGGGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFANP
PFKSTARFTLNPNPAGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRG
AYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFRE
GDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIK
PSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVW
SLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKD
ESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1227 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggtaccccgggc
cccgtggggtccccggcgccgggccacccggccgtcagcagcatgcagggctttcagata
aacttctgtgaaaaggcacaaagtaaacgtaaagcactgaagttgaattttgcaaatcca
cctttcaaatctacagcaaggtttactctgaatcccaatcctgcaggagttcaaaaccca
cacatagagagactgagaacacacagcattgaatcgtcaggaaaactgaagatctcccct
gagcaacactgggatttcactgcagaggacttgaaagacctcggagaaattggacgagga
gcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatggcagttaaa
agaattcggtcaacggtggatgaaaaagaacaaaaacaactccttatggatttggatgta
gtgatgcggagtagtgactgcccgtacattgttcagttttatggtgcactcttcagagag
ggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttacaaatat
gtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcactttagca
actgtgaaagcactaaaccacttaaaagaaaacttgaaaattattcacagagatatcaaa
ccttccaatattcttctggacagaagtggaaatattaaactctgtgactttggcatcagt
ggacaacttgtggactccattgccaagacaagagatgctgggtgcaggccatacatggca
cccgagagaatagacccgagtgcgtcacgacaaggatatgacgtccgctctgatgtctgg
agtttggggatcacactgtacgagttggctacaggccggtttccttatccaaagtggaat
agtgtatttgatcagctaacacaagtcgtgaaaggagatcctccacagctgagtaactct
gaggaaagggaattctccccaagtttcatcaactttgtcaacttgtgccttacgaaggat
gaatccaaaaggccaaagtataaggaacttctgaaacacccctttatcctgatgtacgag
gagcgagctgtggaggtcgcatgctatgtctgcaagatcctggatcagatgcccgctacc
cccagctcccccatgtatgtggactga

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