Vicugna pacos (alpaca): 102542351 Help Entry 102542351         CDS       T08098                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X2   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism vpc  Vicugna pacos (alpaca) Pathway vpc00010   Glycolysis / Gluconeogenesis vpc00620   Pyruvate metabolism vpc01100   Metabolic pathways vpc01200   Carbon metabolism vpc01230   Biosynthesis of amino acids vpc04910   Insulin signaling pathway vpc04930   Type II diabetes mellitus vpc04932   Non-alcoholic fatty liver disease vpc04950   Maturity onset diabetes of the young Module vpc_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate vpc_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:vpc00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102542351 (PKLR)    00620 Pyruvate metabolism     102542351 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102542351 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102542351 (PKLR)    04950 Maturity onset diabetes of the young     102542351 (PKLR)    04932 Non-alcoholic fatty liver disease     102542351 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:vpc04147]     102542351 (PKLR) Enzymes [BR:vpc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      102542351 (PKLR) Exosome [BR:vpc04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    102542351 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Neuregulin Motif Other DBs NCBI-GeneID:  102542351 NCBI-ProteinID:  XP_006214704 UniProt:  A0A6I9IKQ5 LinkDB All DBs Position 21 AA seq 593 aa AA seqDB search MSVQEDMQPQGLWLSKSQRDLAKSILIGAPGGKKEQQMERRGKDRQPCNDMEGPAGYLRR ASVAQLTQELGIAFFQRQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSV ERLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAVESFATSPFSYRPVAIALDTKGPE IRTGILQGGPASEVQLVKGSQVLVTVDLEFRTRGDANTVWVDYPNIVRVVPVGGRIYIDD GLISLVVKKIGPEWLETQVENGGVLGSRKGVNLPGTQVDLPGLSEQDVQDLRFGVEHGVD IIFASFVRNASDVAAVRAALGPEGQGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLG IEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADC IMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVE AAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPVLYREPP EAIWADDVDRRVQFGIESGKLRGFLRSGDLVIVVTGWRPGSGYTNIMRVLSIT NT seq 1782 nt NT seq  +upstreamnt  +downstreamnt atgtcagtgcaggaggacatgcaaccccaggggctttggctctctaagtctcagagggat ttagcaaagtccatcctgattggggctccaggaggtaagaaggagcaacagatggagaga agggggaaagacagacagccgtgcaacgacatggaggggccagcagggtacctgcggcgg gccagcgtggcccaactgacccaggagctgggcattgccttcttccagcggcagcagctg ccggcagccatggcagacaccttcctggaacacctctgcctgctggacattgactccgag cccgtggccgctcgcagtaccagcatcattgccaccatcgggccggcatctcgctccgtg gagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgactcaacttctcccac ggctcccacgagtaccacgctgagtccatcgccaacatccgggaggcggtggagagcttt gcaacttccccgttcagttaccgacccgtggccatagctctggacaccaagggaccggag atacgcactgggatcctgcaggggggcccggcgtcggaagtgcagctagtgaagggctcc caggtgctagtgaccgtggacctggagttccggacgcggggggacgcgaacaccgtgtgg gtggactaccccaatatcgtccgggtcgtgccggtggggggccgcatctacattgacgac gggctcatctccctagtggtcaagaaaatcggtccagagtggctagagacccaagtggaa aatggcggtgtcctgggcagccggaagggcgtgaacttgccgggcacccaagtggacctg cccgggctgtctgagcaagatgtccaggacctgcgcttcggggtggaacatggcgtggac atcatctttgcctcctttgtgcggaatgccagcgacgtggctgccgtcagggctgctctg gggccggaaggacagggcatcaagatcattagcaaaattgagaaccatgaaggggtcaag aagtttgatgaaatcctggaagtgagcgatggcattatggttgcacggggtgacctgggc attgagatcccagcggagaaggttttcctggctcagaagatgatgattggccgttgcaac ttggcgggcaagcctgtcgtctgtgctacacagatgttggagagcatgatcactaagcct cggccaactcgggcagagacaagtgatgtggccaatgccgtgctggatggagcagactgc atcatgctgtcgggggagactgccaagggcaactttcctgtggaggctgtaaagatgcag catgcgattgcccgggaggcagaggctgcagtgtaccaccggcagctctttgaggagctg cgccgggcggcaccgctgagccgggatcccacagaggtcaccgctatcggcgctgtggag gctgccttcaagtgctgtgccgctgccatcatcgtgctgaccacaactggccgttcagca cagcttctgtctcggtaccgacctcgggcagcagtcattgctgtcacccgctctgcccag gctgcccgccaggcccacctatgccgaggagtcttccctgtgctctaccgtgaacctcca gaggccatctgggcagacgatgtggatcgccgggtccaatttggcattgaaagtggaaag ctccgtggcttcctccgttctggggacctggtgattgtggtgacaggctggcgaccaggc tctggctacaccaacatcatgcgagtgctgagcataacctga

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