Vicugna pacos (alpaca): 102542381 Help Entry 102542381         CDS       T08098                                  Symbol TOP2B Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism vpc  Vicugna pacos (alpaca) Pathway vpc01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:vpc00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102542381 (TOP2B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:vpc03032]     102542381 (TOP2B)    03036 Chromosome and associated proteins [BR:vpc03036]     102542381 (TOP2B) Enzymes [BR:vpc01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102542381 (TOP2B) DNA replication proteins [BR:vpc03032]  Eukaryotic type   DNA Topoisomerases    102542381 (TOP2B) Chromosome and associated proteins [BR:vpc03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102542381 (TOP2B)   Centrosome formation proteins    Centriole proteins     102542381 (TOP2B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c DUF7180 Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102542381 NCBI-ProteinID:  XP_006205373 UniProt:  A0A6I9I7C4 LinkDB All DBs Position 1 AA seq 1542 aa AA seqDB search MWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWN NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TACKEYKHSFKQTWLNNMMKTSEAKIKHFDGEDYTCITFQPDLAKFKMEKLDKDIVALMT RRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHI WVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQ TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDR YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKK HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD GFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN INLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ ELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY HTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK EFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQR GYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEE LIKQRDAKGREVSDLKRKSPSDLWKEDLAAFVEELERVEAQEREDVLAGMAGKAIKGKVG KPKVKKLQLEETMPSPYGRRVVPEITAMKADASKKLLKRKKGDLDTTTVKVEFDEEFGGT PVEGTGEEVLISSAPINKGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNPWSDDESK SESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEELKVKASPI ANDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFGSLFSFPSYSQKSEDDSA KFDSNEEDSASVFSPSFGLKQTEKVPSKTVAAKKGKPSLDTTPKPKRTPKQKKVETVNSD SDSEFGIPKKTAAPRGKGRGAKKRKASGSENEGDYNPGRRTSKPPSKKPKKTSFDQDSDV DLFPSDFTSEPPSLPRSGRARKEVKYFADSDEEDDVDFAMFN NT seq 4629 nt NT seq  +upstreamnt  +downstreamnt atgtgggtatatgatgaagatgtaggaatgaattgcagagaagttacctttgtgccaggt ttatacaagatctttgatgaaattttggttaatgcagctgacaataagcaaagggataag aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaat aatgggaaaggcattccagttgtagaacacaaagtagagaaagtttatgttcctgcatta atttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggt ggtcgcaatggttacggtgcaaaactttgtaatattttcagtacaaagtttacagtagaa actgcttgcaaagaatacaaacatagttttaagcagacatggctgaataatatgatgaag acttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaa ccagatctggccaaatttaagatggaaaaacttgacaaggatattgtggctctcatgacc agaagagcttatgatttggctggttcatgcaaaggagtcaaggttatgtttaatggaaag aaactgcctgtaaatggctttcgcagttatgtagatctttatgttaaagacaaactggat gaaactggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt ctcacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaacaaca aaaggtggacggcatgtggattatgtagtagaccaagttgtcggtaaactgattgaagta gttaagaaaaagaacaaggctggtgtatcagtgaaaccatttcaagtaaaaaaccatata tgggtttttattaattgccttatcgaaaatccaacttttgattctcagactaaggaaaac atgactctgcaacccaaaagttttgggtccaaatgccagttgtcagagaagttttttaaa gcagcctctaactgtggcattgtagagagtatcctgaactgggtgaaatttaaggctcag acacagctgaacaagaagtgttcctcagtaaagtacagtaaaatcaaaggtattcccaaa ctggatgatgctaatgatgctggtggcaagcattcccttgagtgtacactgatactaaca gaaggagactctgccaaatcgttggctgtgtctggattaggtgtgattgggagagacaga tacggagtctttcccctcagggggaaaattcttaacgtacgggaagcttctcataaacag atcatggaaaatgcagaaataaacaatattatcaaaatagttggtctacagtacaagaaa agttatgatgatgcagaatctctgaaaactctacgctatggaaagataatgattatgact gatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaac tggccatcacttttgaagcatggtttccttgaagagttcattactcctattgtaaaggct agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaa catatagaaaaccagaaagcctggaaaataaaatactacaaagggctgggtaccagtaca gctaaagaagcaaaggagtattttgctgatatggaaaggcaccgcatcttatttagatat gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagatcgatgac agaaaagaatggttaacaaatttcatggaagatcggagacagcgtaggttacatggctta ccagagcaatttttatatggtacagcaacaaaacatttgacttacaatgatttcatcaac aaagaattgattctcttctcaaactcagacaatgaaaggtctataccatctcttgttgat ggctttaaaccaggccaacgaaaagttttatttacctgttttaagaggaatgataaacgc gaagtgaaagttgcccagttggctggatctgtggctgagatgtccgcttaccatcatgga gaacaagcattgatgatgactattgtgaatttggctcaaaactttgtgggaagtaacaac attaacttgcttcagcctattggtcagtttggaactcggcttcacgggggcaaagatgct gcaagtcctcgttatattttcacaatgttaagctctctagcaagactgctttttcctgct gtggatgacaacttgcttaaattcctttatgatgataatcaacgtgtagagcctgagtgg tatattcccataattcccatggttttaataaatggtgctgagggcattggtacaggatgg gcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctg gatggcttggatcctcatcccatgctgccaaactacaaaaactttaaaggaactatccaa gaacttggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacaca gtagagattacagagcttccagttagaacttggacacaggtgtacaaagaacaggtttta gaacctatgctaaatggaacagataaaacaccagcattaatttctgattataaagaatat catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagctcaagca gaagctgctggattgcacaaagtttttaaacttcagactactcttacttgtaattccatg gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattttaaaa gaattctttgatttacggttaagctattatggtttacgtaaagaatggcttgtaggaatg ttgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaa gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag gaagaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccct gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa ctgattaaacagagagatgcaaaagggagagaggtcagtgatcttaaaagaaaatctcct tcagatctttggaaagaagatttagcagctttcgttgaagaactggagagagtggaagcg caagaacgagaagacgttctagctggaatggctggaaaagcaataaaaggtaaagttggc aaacctaaggtgaagaagcttcaactggaagagacaatgccctcaccttatgggagaaga gtggttcctgaaattactgctatgaaggcagatgccagtaaaaagttgctgaagaggaaa aagggcgatcttgataccacaacagtgaaagtggaatttgatgaagaattcggtgggaca ccggtagaaggcacaggagaagaggtgctgatctcgtcagcgcctataaataaaggcccc aaacccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacccacatcttct gggaaacccagcgcgaagaaagtgaagaaacggaatccctggtcagatgacgaatccaag tcagaaagtgacttggaagaaacagaacctgtggttattccacgagattctctgcttagg agagcagctgctgaaaggcctaagtacacgtttgatttctcagaagaagaggatgatgat gctgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatctcccata gcaaatgatggagaagatgaatttgttccttcagatggccttgataaagatgaatataca ttttcaccaggcaaatcgaaagctactccggaaaagtcttcccacgacaagaaaagtcag gattttgggagtcttttctcatttccttcatactctcagaagtcagaagatgattcagct aaatttgacagtaatgaagaagattctgcttctgttttttcaccatcgtttggtctgaaa caaacagaaaaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtctttagat acaacccctaagcccaagagaactcccaagcagaagaaggtagagactgtgaactctgat tcggactccgagttcggcattccaaagaagaccgcggcgccgagaggtaaaggccgaggg gcaaagaaaaggaaggcatctggctctgaaaatgaaggtgattataaccctggcaggaga acttccaaaccaccaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtg gacctcttcccatcagacttcacttctgaacccccctctctgccacgcagcgggcgggct aggaaagaagtaaaatacttcgcagactctgacgaagaagatgatgttgattttgcaatg tttaattaa

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