Vicugna pacos (alpaca): 102544377
Help
Entry
102544377 CDS
T08098
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00010
Glycolysis / Gluconeogenesis
vpc00020
Citrate cycle (TCA cycle)
vpc00620
Pyruvate metabolism
vpc00785
Lipoic acid metabolism
vpc01100
Metabolic pathways
vpc01200
Carbon metabolism
vpc01210
2-Oxocarboxylic acid metabolism
vpc04066
HIF-1 signaling pathway
vpc04922
Glucagon signaling pathway
vpc05230
Central carbon metabolism in cancer
vpc05415
Diabetic cardiomyopathy
Module
vpc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102544377 (PDHA1)
00020 Citrate cycle (TCA cycle)
102544377 (PDHA1)
00620 Pyruvate metabolism
102544377 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102544377 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102544377 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102544377 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102544377 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102544377 (PDHA1)
Enzymes [BR:
vpc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102544377 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
102544377
NCBI-ProteinID:
XP_006217769
UniProt:
A0A6I9INH5
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSSLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaacgatgctacatttgaaattaagaaa
tgcgatcttcaccggctggaagagggccctcctgtcactacggtgctcaccagggaggac
gggctcaaatactaccgaatgatgcagactgtgcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacctgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggctggaataaaccccacagaccatctgatcacagcctaccgggct
catggctttacctttactcgtgggctttctgtccgagaaattctcgcagaacttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcaatgcatatgtatgccaagaacttc
tacgggggcaatggcattgtgggagctcaggtgcccttgggagctgggattgctctggcc
tgtaagtataatggaaaagatgaggtctgtttgactttgtatggcgatggtgctgctaat
cagggtcagatattcgaagcttacaacatggcagctttgtggaagttgccttgtattttc
atctgtgagaataaccgctatggaatgggaacatctgtggagagggcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgagaggccacgaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccacggacacagcatgagtgatcccggagtcagt
tatcgtacacgagaagaaatacaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggataggatggtgaacagcagtcttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgctacagccgatcctgaaccacct
ttggaagaactcggctatcacatctactgcagtgatccgccttttgaagtccggggtgca
aaccagtggatcaagtttaaatccatcagttaa
DBGET
integrated database retrieval system
