Vicugna pacos (alpaca): 102545159
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Entry
102545159 CDS
T08098
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00020
Citrate cycle (TCA cycle)
vpc00480
Glutathione metabolism
vpc01100
Metabolic pathways
vpc01200
Carbon metabolism
vpc01210
2-Oxocarboxylic acid metabolism
vpc01230
Biosynthesis of amino acids
vpc04146
Peroxisome
vpc05230
Central carbon metabolism in cancer
Module
vpc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
vpc_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102545159 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102545159 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
102545159 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102545159 (IDH2)
Enzymes [BR:
vpc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
102545159 (IDH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
102545159
NCBI-ProteinID:
XP_006198510
UniProt:
A0A6I9HZR2
LinkDB
All DBs
Position
27
AA seq
504 aa
AA seq
DB search
MGRRARAAPPQPYPRGPLLASLRSPPPGSREQRPALGSPLIQLVRLPARPFGMAGYLRVL
RSLCRASGSGPAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKE
KLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKL
KKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADR
AGTFKVVFTPKDGSGAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIRKKWPLYM
STKNTILKAYDGRFKDIFQEIFEKHYKTEFDKNKIWYEHRLIDDMVAQVLKSSGGFVWAC
KNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNP
IASIFAWTRGLEHRGKLDGNQDLMRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLN
EHFLNTSDFLDTIKNNLDKALGQQ
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atggggaggcgggcccgggcagccccgccccagccttacccgcgcggcccgctcctggca
agcctccgcagcccgccgccaggcagccgggagcagcggccggcgctcggatctcccttg
atccagttggttcgcttgcctgcccgaccgttcgggatggctggttacctgcgggtctta
cgctcgctctgcagagcctccggctccgggccggcctgggcaccggcagccctgacagcc
cccaacttgcaagagcagccgcggcgccactatgctgacaagaggatcaaggtggcgaag
ccagtggtggagatggatggcgatgagatgacccgtatcatctggcagttcatcaaggag
aagctcatcctgccgcacgtggacgtccagctcaagtattttgacctggggcttccaaac
cgggaccagaccaatgatcaggtcaccatcgactcagcgttggccacccagaagtacagt
gtggctgtcaagtgtgccaccatcacccccgatgaggcccgtgtggaagagttcaagctg
aagaagatgtggaagagtcccaatggaaccatccggaacatccttggggggactgtcttc
cgggagcccatcatctgtaaaaacatcccacgcctcgtgcctggctggaccaagcccatc
accattggcaggcacgcccacggcgaccagtacaaggccacagacttcgtggctgaccgg
gccggcacgttcaaggtggtcttcaccccgaaggacggcagtggcgctaaggagtgggag
gtgtacaacttccctgctggcggcgtgggcatgggcatgtataacacggacgagtccatc
tcgggttttgcgcacagctgcttccaatatgccatccggaagaagtggccgctgtacatg
agcaccaagaacaccattctgaaagcctatgacgggcgcttcaaggacatcttccaggag
atctttgagaagcactataagaccgagttcgacaagaacaagatctggtacgagcaccgg
ctcattgacgacatggtggctcaggtcctcaagtcttcaggtggctttgtgtgggcctgc
aagaactatgatggagacgtgcagtcggacatcctggcccagggctttggctcccttggc
ctgatgacgtccgtgctggtctgcccggatgggaagaccattgaggctgaggctgctcat
gggactgtcactcgccactatcgggagcaccagaagggccggcctaccagcaccaacccc
atcgccagcatctttgcctggacacgtggcctagagcaccggggaaagttggacggaaac
caagatctcatgaggtttgcccagaccctggagaaggtgtgcgtcgagacagtggagagt
ggagccatgaccaaggacctggcaggctgcatccacggcctcagcaatgtgaagctgaac
gagcacttcctgaacacctcggacttcctggacaccatcaagaacaacctggacaaagct
ctgggccagcagtag
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