Vicugna pacos (alpaca): 102545414 Help Entry 102545414         CDS       T08098                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism vpc  Vicugna pacos (alpaca) Pathway vpc01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:vpc00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102545414 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:vpc03032]     102545414 (TOP2A)    03036 Chromosome and associated proteins [BR:vpc03036]     102545414 (TOP2A) Enzymes [BR:vpc01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102545414 (TOP2A) DNA replication proteins [BR:vpc03032]  Eukaryotic type   DNA Topoisomerases    102545414 (TOP2A) Chromosome and associated proteins [BR:vpc03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102545414 (TOP2A)   Centrosome formation proteins    Centriole proteins     102545414 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102545414 NCBI-ProteinID:  XP_006214340 UniProt:  A0A6I9IMT8 LinkDB All DBs Position 16 AA seq 1533 aa AA seqDB search MEVSPLQPVNENMQVNKAKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ MWVYDEDIGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVIIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMNNMGKAGEMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGSKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRLLMDGAEPLPMLPSYKNFKGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTALDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVADSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQIGLPGKGGKA KGKKTQMAEVLPSPCGKRVIPQVTIEMKAEAEKKIKKKIKNENTEGNPQEDGMEVESLKQ RLEKKQKREPGTKTKKQTTLPFKPVKKAKKRNPWSDSESDMSSNESNFDVPPREKEPRRA AAKTKFTVDLDSDEDGSDFDEKTQDEDFVPSDASSLKTKTSPKHTNKELKPQRSAKSVMD FDADDAEDNVAPSPSSPAADFPAVTETINPVSKKNVTVKKTAAKSQSSTSTTGAKKRAAP KGTKKDPDMDSDVSKKPNPPKTKGRRKRKPSTSDDSDSNFEKMISKAVTSKKSKEESDEF HVDLDSAVASRAKSGRTKKPIKYLEESDEDDLF NT seq 4602 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcgccactgcagcctgtaaacgaaaatatgcaagtcaacaaagcaaagaaa aatgaagatgctaagaaaagactgtctattgagagaatctatcaaaagaaaacgcaattg gaacatattttgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa atgtgggtttacgatgaagatattggcatgaactatagggaagtcacttttgttcctggt ttatacaagatctttgatgagattctggtcaatgctgcagacaacaaacaaagggatcca aaaatgtcttgtattagagtcataattgacccggaaaacaatttaattagtatatggaat aatggaaaaggtattcctgttgttgaacacaaagtcgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgaagaaaagaaagtaacaggt ggtcgaaatggctatggagccaaattgtgtaacatatttagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacgtggatgaataacatggggaaa gctggtgagatggaactcaagcccttcaatggagaagattatacatgtattaccttccac cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt agaagagcatatgatattgctggatctactaaagatgtcaaggtctttctcaatggaagt aagcttccagtaaaaggattccgaagctatgtagatatgtatttgaaggataaggtagat gaaactggcaatccattgaaaattatccatgaacaagtaaaccacaggtgggaagtgtgt ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt gtgaagaagaagaacaaaggtggtgttgcagttaaagcacatcaggtaaaaaatcacatg tggatctttgtgaatgccttaattgaaaacccaacctttgactcccagacaaaagagaac atgactttacaagtcaagagctttggatcaacatgccagttgagtgaaaaattcatcaaa gctgcaacgggctgtggtattgtagaaagcatactaaactgggtgaaatttaaggcccag atccaattaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattcccaaa cttgatgatgccaatgatgcagggggccgaaactcaacggagtgtacacttatcctgaca gagggagactcagctaaaactttggctgtttcaggccttggtgtggttggaagagacaaa tatggggtttttcctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag ataatggaaaatgctgaaattaacaatataatcaagattgtgggtcttcagtataagaaa aactatgaagatgaagattcattgaagactctacgttatgggaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccaccacaac tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg tctaaaaataagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt tctacaccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcaca tcaaaagaagctaaagaatatttcgcagatatgaaaagacatcgtatccaattcaaatat tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat cgaaaggaatggttaactcatttcatggaagatagaaggcaacgaaagttacttggcctt cctgaggattacttatatgggcaaactaccacatatctgacatacaatgacttcataaac aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtagat ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga gaggtgaaagttgcccagctagctggatcagtagctgagatgtcctcatatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcacacattgaagtttttatatgatgacaaccagcgtgttgagcctgaatgg tacattcctattatacccatggtgctgataaatggcgctgaaggaattggtactggctgg tcctgcaaaatccccaactttgatgttcgtgaggttgtgaataacatcagacttttgatg gatggagcggaacctttgccaatgcttccgagttacaagaatttcaagggtactattgaa gagctggctccaaatcaatatgtgattagtggtgaagtagctattcttaattctacaacc attgaaatctcagaacttcccatcagaacatggacccagacatacaaagaacaggttcta gaacccatgttgaatggcactgagaagacgccccctctcataacagattatagggaatac catacagacaccactgtcaagtttgttgtgaagatgactgaagaaaaactggcagaggca gagagagctggactacacaaagtcttcaaactccaaactagtctcacatgcaactcgatg gtgctttttgaccatgtaggctgtttaaagaaatacgacacagcattggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg cttggcgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaatcatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg ggatatgattcggatcctgtgaaggcttggaaagaagcccaacaaaaggttccagatgaa gaagaaaatgaagagagtgacaatgaaaaggaaactgagaagagtgactctgtagcagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaaccaaggaaaag aaagatgaactgtgcaaactaagaaatgaaaaagagcaagagctggaaacattaaagaga aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagagctggaggct gttgaagcaaaggaaaaacaagatgaacaaataggacttcctgggaaaggagggaaggca aagggaaaaaaaacgcaaatggctgaagttttgccttctccatgtggaaaaagagtcatc ccccaagtgaccatagagatgaaagcagaggctgaaaagaaaatcaaaaagaaaattaag aatgaaaatactgaaggaaaccctcaagaggatgggatggaagtagaaagcctaaaacag agattggagaagaaacagaaaagagaaccaggtaccaagacaaagaaacaaactacattg ccatttaaaccagtcaagaaagcaaagaagagaaacccttggtctgattcagaatcagat atgagcagtaatgaaagtaactttgatgtccctccacgagaaaaagagccacggagagca gcagcaaaaaccaaattcacagtggatttggattcagatgaagatggctcagattttgat gaaaaaactcaagatgaagattttgtcccatcagatgctagttcacttaagaccaaaact tccccaaaacatactaacaaagaactcaagccacagagaagtgccaagtcagtaatggac tttgatgctgatgatgccgaggataatgtagcaccttctccaagctctcctgctgctgat ttcccagctgtaactgaaactataaaccccgtttctaaaaagaatgtgacagtgaagaag acggcagcaaaaagtcagtcttccacctccactacaggtgccaaaaaaagggctgcacct aaaggaaccaaaaaagatccagacatggattctgatgtctctaaaaagcctaatcccccc aaaaccaaaggtcgccgcaaaaggaagccttccacttctgatgattctgattctaatttt gagaaaatgatttctaaagcagtcacaagcaagaaatccaaggaggagagcgatgagttc catgtggacttagactcagctgtggcttctcgggcaaaatctggaaggacaaagaaacct ataaagtacctcgaagaatcagatgaagatgacctgttttaa

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