Vicugna pacos (alpaca): 102545985 Help Entry 102545985         CDS       T08098                                  Symbol NF1 Name (RefSeq) neurofibromin isoform X1   KO K08052   neurofibromin 1 Organism vpc  Vicugna pacos (alpaca) Pathway vpc01521   EGFR tyrosine kinase inhibitor resistance vpc04010   MAPK signaling pathway vpc04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:vpc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102545985 (NF1)    04014 Ras signaling pathway     102545985 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102545985 (NF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 MIF4G_like_2 Motif Other DBs NCBI-GeneID:  102545985 NCBI-ProteinID:  XP_031541155 UniProt:  A0A6J3B2I4 LinkDB All DBs Position 16 AA seq 2818 aa AA seqDB search MRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREG NQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDC AKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAE KLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFLDSLRKAL AGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRG SQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSTFKHGL GTASALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKF KEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSH MPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEIL KWLREILICRNKFLLKNKQADRSSCHFLFLYGVGCDVPSSGNTSQMSMDHEELLRTCTPG TSLRKGKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCE EADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTE AWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQ EWINMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFM DRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTD TNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKL CQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEA VVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMS RRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDT LAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQ LLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQ HVSFEVDPTRLEQSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHS LLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRI ERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHS LSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVA DTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKT GQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVC AVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEE DLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVD ENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLL NIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTL AANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAIL DKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTA VALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLD VAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTE FSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEA CMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKAL ESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGT ALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLL KGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSL KHRKSLLLTDISMENVSMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAAAYPTAGQTS PRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAET DYEMETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFD QRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESP PQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESL LTPTSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPEYTRCINTSKDMWLEADLCWKFL ESTRRTLNSPPPLATVTVDELAMDPQARCRSKEALAVSNVIALRRSCEAFFLSFFKQT NT seq 8457 nt NT seq  +upstreamnt  +downstreamnt atgagaatatttggagaagctgctgaaaaaaatttatatctctctcagttgattatattg gatacactggaaaaatgtcttgctgggcaaccaaaggacacaatgaggttagatgaaaca atgctggtcaaacagttgctgccagaaatctgccattttcttcacacctgtcgtgaagga aaccaacatgcagctgaacttcggaattctgcctctggggttttattttctctcagttgt aacaacttcaatgcagtcttcagtcgcatttctaccaggttacaggaattaactgtttgt tcagaagacaatgttgatgttcatgatatagaattgttacagtatatcaatgtggattgt gcaaaattaaaacgactcctgaaggaaacagcatttaaatttaaagccctaaagaaggtt gcacagttagcagttataaatagcctggaaaaagcattttggaactgggtagaaaattat ccagatgaatttacaaagctataccagattccacagactgatatggctgagtgtgcagaa aaactgtttgacttggtagatggttttgctgaaagcaccaaacgtaaagcagcagtttgg ccactacagatcattctccttatcttgtgtccagaaataatccaggatatatccaaggat gtggttgatgaaaacaacatgaataagaagttgtttctggacagtctacgaaaagcactc gctggccatggaggaagcaggcagctgactgaaagtgctgccatcgcctgtgtcaaactg tgtaaagcgagtacttacatcaattgggaagataattctgttattttcctactagttcag tccatggtggttgatcttaagaacctgctttttaatccaagtaaaccattctcaagaggc agtcagcctgcagatgtggatctcatgattgactgtctagtttcttgctttcgtataagc cctcacaacaaccaacacttcaagatctgtctggctcagaattccccttctacatttcac tatgtgctggtaaattcactccatcgaatcatcaccaatagcactttcaagcatggactt ggcactgcttctgcactggattggtggcctaagattgatgctgtatattgtcactcagtt gaacttcggaatatgtttggtgaaacacttcataaagcagtccagggttgtggagcacac ccagcgatacgaatggcaccgagtcttacatttaaagaaaaagtgacaagccttaaattt aaagaaaaacctacagacctagagacaagaagctataaatatcttctcttgtccatggtg aaactaattcatgcagatccgaagctcttgctttgtaatccaagaaaacaggggcctgaa acccaaggcagtactgcagaattaattacagggcttgtgcaactagtccctcagtcacat atgccagagattgctcaggaagcaatggaggctctgctggttcttcatcagttagatagc attgatttgtggaatcctgatgctcctgtagaaacattttgggaaattagctcacaaatg cttttttacatctgcaagaaattaactagccatcaaatgcttagtagcacagaaattctg aaatggttgcgggaaatcttgatctgcaggaataaatttcttcttaaaaataagcaggca gatagaagttcctgtcactttctcttcctttatggagtaggatgtgatgttccttcaagt ggaaataccagtcagatgtccatggatcatgaagagttactacgtacttgtactcctgga acctctctccggaaagggaaaggaaactcatccatggatagtgcagcagggtgcagtgga accccaccaatatgccgacaagcccagaccaaactagaggtggccctgtacatgtttctg tggagccctgacactgaagctgttctggttgccatgtcctgttttcgtcacctctgtgag gaagcggatatccggtgtggggtggatgaagtatcagtgcacaacttcttgcccaactat aacacattcatggaatttgcctctgtcagcaatatgatgtcaacaggaagagcagcactt cagaaaagagtgatggcactactacggcgaattgagcatcccactgcgggaaacacggag gcttgggaagatacacatgcaaagtgggaacaagctacaaaactaatcctcaactaccca aaagccaaaatggaagatggccaggctgctgaaagccttcacaagaccattgttaagagg cgaatgtctcatgtgagtggaggaggatccatagatttgtctgacacagactccctgcaa gaatggatcaacatgactggcttcctttgtgcccttgggggagtgtgcctgcagcagaga agcaattctggcctggcaacctatagcccacccatgggcccagtcagtgaacgcaagggt tccatgatttcagtgatgtcctcagagggaaacgcagatacacctgtcagcaaatttatg gatcggctgctatccttaatggtctgtaaccatgagaaagtgggacttcagatacggact aatgttaaggatctggtgggtctagaactgagtcctgctctttatccaatgctcttcaat aagttgaagaataccatcagcaagttttttgactcccaaggacaggttttattgactgac accaatactcaatttgtggagcaaaccatagctataatgaagaacttactagataatcat actgaaggcagctctgaacatctggggcaagctagcattgaaacaatgatgttaaatctg gtcaggtatgttcgtgtgcttgggaatatggtccatgcaattcaaataaaaacgaaactg tgtcagttagttgaggtaatgatggcaaggagagacgacctctcattttgtcaagagatg aaatttaggaataagatggtagaatacctgacagactgggttatgggaacatcaaaccaa gcggcagatgacgatgtgaaatgtcttacgagagatttggaccaggcaagcatggaagca gtagtttcactcctggctggtcttccgctgcagcctgaggaaggagatggtgtggaactg atggaagccaaatcacagttatttcttaagtatttcacattgtttatgaaccttttgaat gactgtagtgaagttgaagatgaaaacgcacaaacaggtggcaggaaacgtggcatgtct cggaggctggcatcactgaggcactgtacagtcctggcaatgtcaaacttgctcaatgct aacgtggacagtggcctcatgcactccataggtttaggttatcacaaagatctgcagaca agagctacgtttatggaagtgctgacaaaaatcctccaacaaggcacagaatttgacaca cttgcagagacggtgttggcagatcgttttgagagactggtggagttggtcacgatgatg ggtgatcagggagagctccctatagctatggctctagccaatgtggtcccttgttctcag tgggatgaactagctcgagttctagtgactctgtttgactctcggcatttactctaccaa ctgctctggaacatgttttctaaggaagtagaattggcagactctatgcagactcttttc cgaggcaacagcttagccagtaaaataatgaccttctgtttcaaggtatatggtgctacc tacctacaaaaactcctggatcctttattacgcattgtgatcacatcttctgattggcaa catgttagctttgaagtggatcctaccaggttggaacagtcagagagccttgaggaaaac cagcgaaacctccttcagatgactgaaaagttcttccatgccatcatcagttcctcctcc gaattcccccctcagctacgaagcgtttgccactgtttgtaccaggcaacttgccactcc ctactgaataaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccag cgtttccctcagaacagcatcggtgcagtaggaagtgccatgttcctcagatttatcaat cctgccattgtctcaccatatgaagcagggattttagataaaaagccaccacctagaatc gaaaggggcttgaagttaatgtcaaagatacttcagagtattgccaatcatgttcttttc acaaaagaagagcatatgcggccttttaatgattttgtgaaaagcaactttgatgcagca cgaaggttttttcttgatatagcatctgattgccctacaagtgatgcagtaaatcacagt ctttccttcatcagtgatggcaatgtgcttgctttacatcgtctactctggaacaatcag gagaaaattggccagtatctttccagcaacagggatcacaaagctgttggaagacgacct tttgataagatggcaacacttctcgcatacctgggtcctccagagcacaaacctgtggca gatacacactggtccagccttaaccttaccagttcaaagtttgaggaatttatgactagg catcaagtacatgaaaaagaagaattcaaggctttgaaaacattaagtattttctaccaa gctgggacttccaaagctgggaatcctatattttattatgttgcacggaggttcaaaact ggtcaaatcaatggtgatttgctgatataccatgtcttgctgactttaaagccatattat gcaaagccatatgaaattgtagtggaccttacccatactgggcctagcaatcgctttaaa acagactttctctccaagtggtttgttgtttttcctggctttgcttacgacaatgtctgt gcagtttatatctataactgtaactcctgggtcagggagtataccaagtaccatgagcgg ctgctgactggcctcaaaggcagcaaaaggctcattttcatagactgtcctgggaaactg gctgagcacattgagcatgaacaacagaaactacctgctgccacgttggctttagaagag gatctgaaggtattccacaatgctctcaagctagctcacaaagacaccaaagtttctatt aaagttggttctaccgctgttcaagtaacctcagctgagcgaacaaaagtcctggggcaa tcagtctttctaaatgatatctattatgcttcggaaattgaagagatctgcctagtggat gagaaccagttcaccttaactattgcaaaccagggcacaccactcaccttcatgcaccag gagtgcgaagccattgttcagtctatcattcacatccggacacgctgggagctgtcacaa cctgactccatcccccagcataccaagattcggccaaaagatgtccctgggaccctactc aatattgcattacttaatttaggcagttcagaccctagtttgcggtcagctgcctataat cttctgtgtgccttaacttgtacctttaatttaaaaatcgagggccagttactagagaca tcaggtttatgtatccctgccaacaacaccctctttattgtctctattagtaagacgctg gcagccaatgagccacacctcaccttagaatttttggaagagtgtatttctgggtttagc aaatccagtattgaattgaaacatctttgtttggaatacatgactccatggctgtcgaat ctagtacgcttttgtaagcacaatgatgatgccaaacgacaaagggttaccgcgattctt gataaactgataacaatgaccataaacgagaaacagatgtatccatctattcaagcaaaa atatgggggagccttgggcagattacagacctccttgatgttgtactggacagtttcatc aaaactagtgcaacaggtggcttgggatccataaaagctgaggtgatggcagatactgct gtagctttggcttctggaaatgtgaaactggtttcaagcaaggttattggaaggatgtgc aaaataattgacaagacgtgcttatctccaacgccgactttagaacagcatcttatgtgg gacgatatcgccattctagcacgctacatgctcatgctgtccttcaacaactcccttgat gtagcagctcacctcccctacctcttccatgttgttactttcttagtagccacagggcca ctctcccttagagcttccacgcatggattggtcattaatatcattcactctctgtgtact tgttcacagcttcattttagtgaagaaaccaagcaagttttgagactcagtctgacagag ttctcattacccaaattttacctgctgtttggcattagcaaagtcaagtcagctgctgtc attgcctttcgctccagttaccgggacaggtcattctctcctggctcctatgagagggag acttttgctttgacatccttggaaacagtcactgaagctttgctggagatcatggaggca tgtatgagagatattccaacatgcaagtggctggaccagtggacagaactagctcaaaga tttgcattccagtataatccatccctgcaaccaagagctctagttgtctttggctgtatt agcaaacgagtgtctcatgggcagataaagcagattatccgaattcttagcaaggcgctt gagagttgcttaaaaggacctgatacttacaacagtcaagttctgatagaagctacagta atagcactaaccaaattacaaccacttcttaataaggactcccctctgcacaaagccctc ttttgggtagctgtggccgtgctgcagctcgatgaggtcaacttgtattcagcaggcacc gcacttctggaacaaaacctgcacaccttggacagtctccggatattcaatgacaagagt ccagaggaagtatttatggcaatccggaatcctctagaatggcactgcaagcaaatggat cattttgttggactcaatttcaactctaactttaacttcgcactggttggacacctctta aaaggatacaggcatccttcacctgcgattgttgcaagaacagtcagaattttgcataca ctactaactctggttaataaacatagaaattgtgacaaatttgaggtgaatacacagagc gtggcttacttggcagctttactcacagtgtctgaggaggttcgaagtcgctgtagccta aaacatagaaagtctcttcttcttactgatatttcaatggaaaatgtttctatggataca tatcccattcaccatggcgaccctagctataggacactaaaggagaatcagccatggtcc tctcccaaaggttctgaagggtaccttgccgccgcctatccaactgcaggccagaccagt ccccgagcccggaaatccatgagcttggacatggggcagccttctcaagccaacacgaag aagttgcttggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaa aggcaagaaatggaatcagggatcacaacaccccccaaaatgaggagagtagcagaaact gattatgaaatggaaactcaaaggatttcctcatcacaacaacacccacatttacgtaaa gtttcagtgtctgaatcaaatgttctcttagacgaagaagtacttactgatccaaaaatc caagcacttcttcttactgttctggctactctggtgaaatataccacagatgagtttgat cagcgaattctttatgaatacttagcagaagccagtgttgttttcccaaaagtttttcct gttgtgcacaatttgttggactctaagatcaacaccctcttgtcattgtgccaagatccg aatttgttaaatccgatccatggaattgtgcagagtgtggtgtaccatgaagaatcccca ccacaataccagacgtcttacctgcaaagttttggttttaatggcctgtggcgatttgca ggacccttttcaaagcaaacacaaatccctgactatgctgagcttattgttaagtttctt gatgccttgattgacacgtatttgcctggaattgatgaagaaaccagtgaggagtccctc ctgacacccacatctccttatcctcctgcagtgcagagccagcttagtattactgctaac cttaacctttctaattccatgacctcacttgcaacttcccagcattccccagaatatact cggtgtataaacaccagtaaggatatgtggctagaagctgacctctgctggaagtttctg gaatcgacaaggagaacgttgaactctcccccaccactggccactgtaacagtggacgaa ctcgccatggatccgcaagccaggtgcagaagcaaagaagcgctggcagtttcaaacgta atagcattaagaagatcgtgtgaagctttctttctttcctttttcaaacagacttaa

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