Variovorax paradoxus B4: VAPA_1c25120
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Entry
VAPA_1c25120 CDS
T02835
Symbol
leuA1
Name
(GenBank) 2-isopropylmalate synthase LeuA
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
vpd
Variovorax paradoxus B4
Pathway
vpd00290
Valine, leucine and isoleucine biosynthesis
vpd00620
Pyruvate metabolism
vpd01100
Metabolic pathways
vpd01110
Biosynthesis of secondary metabolites
vpd01210
2-Oxocarboxylic acid metabolism
vpd01230
Biosynthesis of amino acids
Module
vpd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
vpd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
VAPA_1c25120 (leuA1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
VAPA_1c25120 (leuA1)
Enzymes [BR:
vpd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
VAPA_1c25120 (leuA1)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AGU49612
UniProt:
T1X9M0
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All DBs
Position
1:2668585..2670288
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AA seq
567 aa
AA seq
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MLKQPQAKYRAFAPIGLKDRTWPDAVLTKAPIWLSTDLRDGNQALVEPMDIARKMRMFET
LVAIGFKEIEVGFPSASQIEFDFVRKLIEEDRIPDDVTIQVLTQARDHLIARTFESLQGA
PRAIVHLYNAVAPVMRRVVLGMDEDQIVELASSHARMFNDFAAKQPGTQWTFQYSPEMFS
GTDVVFSKRVVDAVTEVWAPTPQRKCIVNLPTTVEHSTPNIFADMIEWMHRNLARRDAIV
LCVHPHNDRGTGTAAGELALMAGAERIEGCLFGNGERTGNLDLVNVALNLYTQGVSPELD
FSNIDEIRATVEHCNQIPVHPRHPYVGDLVYTSFSGSHQDAIKKAFAARKEGDIWDMPYL
PIDPKDVGRSYEAVIRVNSQSGKGGMAYLLESEYGLEMPRRLQMEFMQTVQRVMDVAGKE
LTAADLWELFVREYGLEAAHSLQHRVIEEEGEGASASVVLRGDLPWDGEIRAIEGRGNGP
IDAFTQALSKATGHTVRVMDYHQHAIGAGADAKSVAYLELRVDEAQTLFGVGIDANVISA
SLKAIVSGVQRARTRGAHSAQSVVELA
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgctgaagcaacctcaagccaaataccgcgcattcgccccgatcggcctcaaggaccgc
acctggcccgatgccgtgctgaccaaggccccgatctggctgtcgaccgacctgcgcgat
ggcaaccaggcgctggtcgagccgatggacatcgcgcgcaagatgcgcatgttcgagacg
ctcgtggcgatcggcttcaaggaaatcgaagtcggctttccctccgcctcgcagatcgaa
ttcgacttcgtgcgcaaactgatcgaggaagaccgcattcccgacgacgtgacgatccag
gtgctgacacaggcgcgcgaccatctcatcgcccgcactttcgaatcgctgcagggggcg
ccgcgcgccatcgtccacctctacaacgccgtggcgcccgtgatgcgccgcgtggtgctc
ggcatggacgaagaccagatcgtcgagcttgccagcagccatgcgcgcatgttcaacgac
ttcgccgcgaagcagccgggcacgcagtggaccttccagtactcgcccgaaatgttctcg
ggcaccgatgtcgtgttctcgaagcgcgtggtcgacgcggtgacggaagtctgggcgccg
acgccgcagcgcaagtgcatcgtcaaccttcccacgacagtcgagcattccacgccgaac
atcttcgccgacatgatcgagtggatgcaccgcaacctcgcgcgccgcgacgccatcgtg
ctgtgcgtgcacccgcacaacgaccgcggcaccggcacggcggcaggcgagctggcgctg
atggcgggcgccgagcgcatcgagggctgcctgttcggcaacggcgagcgcaccggcaat
ctcgacctcgtcaacgtcgcgctcaacctctacacccagggcgtctcaccggagctcgac
ttctcgaacatcgacgagatccgcgcgacggtcgagcactgcaaccagattccggtacat
ccgcgccacccgtatgtgggcgatctcgtctacacctcgttctcgggctcgcaccaggac
gcgatcaagaaggccttcgctgcgcgcaaggagggcgacatctgggacatgccctacctg
cccatcgatccgaaggacgtgggccgcagctacgaggccgtgatccgcgtcaacagccag
tcgggcaaggggggcatggcctacctgctcgaaagcgaatacggcctcgagatgccgcgc
cgcctgcagatggagttcatgcagaccgtgcagcgcgtgatggacgtggccggcaaggag
ctcaccgccgccgacctctgggagctgttcgtgcgcgaatacggcctcgaggccgcgcat
tctttgcagcaccgcgtgatcgaggaagaaggcgagggcgccagcgcctcggtggtgctg
cgcggcgacctgccctgggacggcgagatccgcgccatcgaaggccgcggcaacgggccg
atcgacgccttcacgcaagcactgagcaaggccaccggccataccgtgcgcgtgatggac
taccaccagcacgccatcggcgcgggcgccgatgccaagtcggtggcgtacctcgaactg
cgcgtggacgaggcccagacgctgttcggcgtgggcatcgacgcgaacgtgatctcggct
tcgctgaaggccattgtctcgggcgtgcagcgcgcgcggacccgcggcgcgcacagcgca
caatcggtggttgagctcgcctga
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