Vibrio parahaemolyticus O1 K33 CDC_K4557: M636_20035
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Entry
M636_20035 CDS
T02760
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
vpk
Vibrio parahaemolyticus O1:K33 CDC_K4557
Pathway
vpk00290
Valine, leucine and isoleucine biosynthesis
vpk00620
Pyruvate metabolism
vpk01100
Metabolic pathways
vpk01110
Biosynthesis of secondary metabolites
vpk01210
2-Oxocarboxylic acid metabolism
vpk01230
Biosynthesis of amino acids
Module
vpk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
vpk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
M636_20035
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
M636_20035
Enzymes [BR:
vpk01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
M636_20035
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
NAD_binding_10
Motif
Other DBs
NCBI-ProteinID:
AGQ99304
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All DBs
Position
I:2562894..2564441
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AA seq
515 aa
AA seq
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MNDQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDVIEAGFPISSPGDFESVQT
IAKHIKNSRVCALSRAVAKDIDAAAEALKVADQFRIHTFLATSTIHVQDKLRRSYDDVLE
MAVNAVKHARNYTDDVEFSCEDAGRTPIDNLCRMVEAAIDAGASTINIPDTVGYTVPSEF
GGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAVQAGARQIEGTINGIGERAGNCS
LEEIAMIIKTRQELLGVSTGIKHEEIHRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIH
QDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYKEDEYNLDALYADF
LKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSVMATTSIKMQCGDAEMCE
AAVGNGPVDALYQCIYRVTGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVS
TDIVEASGQALLHVINSIHRADTIAEMKQKKIATV
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgaacgatcaggtcattatattcgacaccaccttgcgtgatggcgagcaagcgttgtca
gcaagcttgacggttaaagaaaaactgcagattgcctatgcgcttgaaaggctgggcgtt
gatgttatcgaagctggttttcctatctcttcccctggcgatttcgagtccgtacaaact
attgcaaaacacatcaaaaatagccgagtttgtgccctttcgcgtgccgttgcgaaagac
atcgatgccgcagctgaagcgctaaaagttgctgaccaattccgtatccacacttttcta
gccacttccacgattcacgttcaagacaagctacgccgcagttacgatgacgtacttgaa
atggcggtcaacgccgttaaacacgcgcgtaactacaccgatgatgtcgaattttcttgt
gaagacgcaggccgaacaccaatcgacaatctatgtcgcatggttgaagccgcgattgat
gctggagcaagcaccatcaacattcccgataccgttggctacacagtgccaagcgagttc
ggtggcatcatccaaacgcttttcaaccgcgtgccgaacatcgacaaggccatcatttct
gtgcactgtcatgatgacttgggcatgtcggtcgcaaactcaattgcagcagtacaagcc
ggtgctcgccaaattgaaggcaccatcaatggtatcggcgagcgtgcgggtaactgctca
ctagaagagatcgcgatgatcatcaagacgcgtcaagagcttctgggcgtaagcacgggg
atcaaacacgaagaaatccatcgtactagcaagttggtgagtcaactgtgcaacatgccg
atccaaagcaacaaagcgatcgtgggtgccaatgcattcagccattcttcaggtatccac
caagacggcatgttaaagaacaagaacacttacgagatcatgacgcctgagtcgattggt
cttaaaaaccaagcgcttaacctaaccagtcgtagcggccgagcggcggtgaagagccac
atggattccatgggttataaagaagatgagtacaacctagacgcactgtacgccgatttc
ttgaaactggccgaccgtaaaggccaagtgtttgattacgatttagaagcactaatgcac
ttctccaacttgcgtgaagaagatgatttctacaagttgaattacctaagcgtgcaatcg
ggcagcgtgatggcaaccaccagcatcaagatgcaatgtggtgatgcggaaatgtgtgaa
gcggcggtcggcaatggtccggttgatgcgctataccaatgtatctaccgcgtgacaggt
tacgagatcgtactagataaattcgatctaaccgcaaaaggtgaaggtgaggatggtcta
ggtcaagcagacatcattgccaactacaaaggtagaaaataccacggtacgggcgtttca
accgatatcgtagaagcttctggtcaagcactattgcatgttatcaacagcatccatcgc
gcagacaccattgccgagatgaagcagaaaaagattgctacggtatag
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