Vibrio paracholerae: SA104470976_00459
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Entry
SA104470976_00459 CDS
T08432
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vpl
Vibrio paracholerae
Pathway
vpl00260
Glycine, serine and threonine metabolism
vpl00261
Monobactam biosynthesis
vpl00270
Cysteine and methionine metabolism
vpl00300
Lysine biosynthesis
vpl01100
Metabolic pathways
vpl01110
Biosynthesis of secondary metabolites
vpl01120
Microbial metabolism in diverse environments
vpl01230
Biosynthesis of amino acids
Module
vpl_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vpl_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vpl_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vpl00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SA104470976_00459 (thrA)
00270 Cysteine and methionine metabolism
SA104470976_00459 (thrA)
00300 Lysine biosynthesis
SA104470976_00459 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SA104470976_00459 (thrA)
Enzymes [BR:
vpl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SA104470976_00459 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SA104470976_00459 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
SYZ80609
LinkDB
All DBs
Position
1:484340..486799
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADPERFLRAADIIVNNAQQEEVAVVLSAPGKTTNKLVAVIESALRQGKA
EAQIVELESSFYALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMCPDNVNA
RIISKGERVSIQLMKAVMEAKGLPANLIDPVKYLLAKGDHLEAMVDVEISTQRFRQSPLP
QQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTLIGQDTG
EDKLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSAADVSIVLITQSSSEYSISF
CIEAQHKALAQQALADAFELELKDGLLEPVEFVDNVAIITLVGDGMRTSRGVASQFFSSL
AEVHVNVIAIAQGSSERAISAVIPDDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIQRQQAKLAEKGIMMRVCGLANSKGMLLDSQGLPLEQWRDRMVNADQAFSLENLVAL
VQRNHIINPVLVDCTSSDEIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRNVARHSR
RKLMYETTVGAGLPVIENLQNLIAAGDELEKFSGILSGSLSFIFGKLDEGMTLSQATLLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELNDVDVEQALPAGFDASGSVEEFMA
RLVQADAAFAERVAQAKAEGKVLRYVAQIVDGQCQVRIVAVDENDPMFKVKEGENALAFY
SRYYQPISLVLRGYGAGSEVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattaaagtttggaggttcatcactggcggatccagagcgttttttacgtgct
gctgatatcatcgtaaataacgcacagcaggaagaggtggccgttgtcctctctgctccg
ggaaaaaccactaataaactggtggcagtgattgaaagtgctttacgtcagggaaaggcg
gaagcgcaaatcgtagagctagagagctcattctatgccttgcttgatggcattaaagcg
cagctcccgaatttggatgacagtgcttatcaacagcaagtgcactcttccatgactcag
ttacgccagtttgtgcatggcattactttgctcggtatgtgcccagacaatgtcaatgcg
cgtattatcagtaaaggtgagcgcgtttccattcaattgatgaaagcggtgatggaagcc
aaaggtctgccggctaatctgattgaccccgtcaaatatctattggcaaaaggtgatcac
cttgaagctatggtcgatgtggaaatctcgactcagcgtttcagacaatcgccgttacca
cagcagcacgtcaatatcatgccgggctttactgcgggtaatgcgcaaggtgagttggtc
tgtttagggcgtaacggttcggattattcagcagcggtactggctgcctgtttacgtgcg
gattgttgcgagatttggacggatgtggatggcgtttacaactgtgatccacgtttagtg
gatgatgcgcgccttcttaaatcgctcagctatcaagaggcgatggagctttcttacttc
ggggcatctgtgctgcatcctaaaaccattgcgccgattgctcaatttcaaattccttgc
ctgatcaaaaacagcttcaatccacaaggtgcaggcaccttgattggccaagatactggt
gaagataagctcgcgatcaaaggtatcaccactctgagcaatctcactatggttaacgtg
tccggccccggaatgaaaggcatggtggggatggcgagccgcgtgtttggcgcgatgtca
gcggccgatgtgtcgatcgtgctcattactcaatcttcttcggaatacagcatcagtttc
tgtatcgaagcacaacataaagctttggcacagcaagcgctggcggatgcatttgaactg
gaactcaaagatggcttgcttgagccggttgagtttgtcgataacgtcgccatcatcacg
ctggttggtgatggtatgcgcacctctcgcggtgtcgcgtcgcaatttttctcatctctg
gccgaagtgcacgtcaacgtgattgcaattgcccaaggctcttctgagcgtgcgatttct
gcggtgatccccgatgataagatttcagaagcgatcaaagcttgtcacgaaaaccttttc
aactctaaacactttttagatgtgtttgtggtcggtgtgggtggcgtgggcggtgagttg
gtggatcaaattcagcgtcaacaagccaagcttgcggaaaaaggcatcatgatgcgcgtt
tgtggactcgctaacagtaaaggcatgctgcttgatagccaaggcttgccgttggagcag
tggcgcgatcgtatggtcaatgcggatcaagcgttcagtttagagaatctagtagctttg
gtgcagcgtaatcatatcattaacccagtattggtggattgcacgtccagtgatgagatt
gctaaccagtatgcggatttcctcgccgcgggtttccatgtggtgaccccgaacaagaaa
gccaataccgctagcatgagttattaccatcagctacgtaatgtagcgcgtcactcgcgt
cgtaaactaatgtatgaaactacagttggcgcgggtctgcccgttatcgaaaacttgcaa
aacctaattgcagcaggggatgagctggaaaaattcagcggtattctctcaggttctctc
tcctttatcttcggtaaattggatgaaggcatgactttgagccaagcaacgctgcttgct
aaagagaaaggctttacagagccagatccgcgcgatgatctctctggtatggatgtggcg
cgtaagttactgattttggcgcgtgaagcggggtacgaattggagctgaacgatgtggat
gttgaacaagctctgcccgctggctttgatgcttcaggcagtgttgaggagttcatggca
cgtttagtgcaagccgatgccgcgtttgccgagcgagtagcgcaagccaaagccgaaggc
aaagtgctgcgctatgtggcgcaaatcgtcgatggccagtgccaagtgcggattgtcgcg
gttgatgaaaacgatcctatgttcaaagtcaaagaaggtgaaaacgcgctggctttctac
agtcgttactatcagcccatctcattggtattgcgtggttacggcgcgggttctgaagtg
actgctgcaggcgtgttctcagatgtgatgcgtacactcggttggaaattaggggtttaa
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