Vespa velutina (Asian hornet): 124946996 Help Entry 124946996         CDS       T09814                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism vve  Vespa velutina (Asian hornet) Brite KEGG Orthology (KO) [BR:vve00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:vve04040]     124946996    04990 Domain-containing proteins not elsewhere classified [BR:vve04990]     124946996 Ion channels [BR:vve04040]  Voltage-gated cation channels   Ryanodine receptor    124946996 Domain-containing proteins not elsewhere classified [BR:vve04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    124946996 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  124946996 NCBI-ProteinID:  XP_047344485 LinkDB All DBs Position 2:13476561..13510182 Genome browser AA seq 5159 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETQQENLGKGTGSGHRTLLYGNAILLRHLNSDMYLA CLSTSSSNDKLAFDVGLQQHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENGLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW NTSPNQNIVTYEGGSVMSQARSLWRLELARTKWAGGFINWLHPMRIRHLTTGRYLGVKEN NELYLVDRNEATIETSTFWLRQEKDDQKIILEDKDLEVIGMPIIKYGDSTVIMQHATTCL WVSYKSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQF ITGLENLQVDRRASMFFQNVNLNEMVMCLEDLINYFAQPEDDMEHEEKQNRFRALRNRQD LFQEEGILNLILEAIDKINVITSQGFLVALSGDESGQAWDQISGYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVGR VEGSALYQKWYFEVTVDHIEQTTHMMPHLRIGWANTAGYMPYPGGGEKWGGNGVGDDLYS FGFDGANFWTGGRKTQIVQNATEPFIRKSDVIGCSLDLTVPVISFTFNGTHVAGTFRNFN LDGMFFPAISCSSKLSCRFLLGGDHGRLKYQPPDEFSPLVESLLPQQILSLDPCFYFGNM NKVVLAGPWLVEDDTAFVPAPVDTSMINLPSYVEQIRDKLAENIHEMWAMNKIEAGWIYG EHRDDLRKIHPCIVQFERLPAAEKRYDTQLAVQTLKTILALGYYITMDKPPSRIKTLRLP NEPFLQSSGYKPAPLDLSAITLTPKMEELVDQLAENTHNLWAKERISQGWTYGLNEDSEM RRSPHLVPYPKVDEAIKKANRDTASETVRTLLVYGYMLDPPTGEQHEALLLEANRLRQLY FRTYRVEKHYAVNSGKWYFEFEVLTAGPMRVGWAKADCMPGSMLGSDENTWAFDGYNVTK VHAGTHESFGHKYQVGDIVGCFIDVADRTISFSLNGELLMDALGGETSFADVQGDSFVPA FTLGVGQKAKLTFGQDVNTLKFFTTCGLQEGYEPFCVNMNRLVTYWYTKDQPIFENTDDM ADTRIDVARIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICQSIFISENDKVRRW QEIKMHQNRLLSEQFEQTQQAAPSAHMEQIMKSGFSMSDIKGLQRNYSEDAVEADEMAKE SPIPMQRNKPTRPPRKGSIYGSRSGAMDSAVNEAEMNGYGEMNGDVKDDKKKRGRSPFRK LSKEMEDVFFSRKAKSPEAKAKTPELQVRSDVSDKSTRTMTGSKTASKTAQIRVSTTDLK VVPPQIPERNAPKIMSVLTGSGVEAIGNEIFDAECLKLMNEYFYGVRIFPGQDPTHVYIG WVTSQYHLHTKDFNLSRVRKASVIITDDYDRPIEQVDRQSCYMVRADELYNEVTQDASGK GASQGMFVGCFIDTATGCISFTCEGKETSHKFKMEPDTKLFPAIFVEATSKEILQIELGR TSTTLPLSAAVLQNSERHVIPQFPPRLKVQCLKPHQWARVPNQSLQVHALKLSDIRGWSM LCEDAISMLALHIPEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNYRAAHALCQH VDQKQLLYAIRAEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEFIIPLGQELKDLYED VEMKHSLRYLQTESVRPQMKMTDIRQIPSSDQVIENIRSLYSPHFPLDVVRDYVMMALNE AVEINQVHNRDPIGGSNENLFLPLIKLVDRLLLVGMLRNEDVMKLLIMINPETWDPTFDK EGKDEHKKGLLHMKMAEGAKLQMCYLLHHLNDIQLRHRVESIIAFSHDFVGDLQSDQLRR YIDIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKNLDPEEDTENCPCGEELVAKMNEF HSDLMSYVSLHALQEAVDAADEPVEEVQKPGAMKKLFNFINAVKELEEEPKPEPEPERKT PEEVFRKVLIATIVKWAEEAQIETPKLVREMFSLLVRQYDTVGELIRALEKTYVINSKTR EDVASMWVGLSQIRALLPVQMSQEEEELVRERLWKLVNNHTFFQHPDLIRVLRIHENVMA IMMNTLGRRAQAQSDAQTQAQTAEGEAAAKEKDTSHEMVVACCRFLCYFCRTSRQNQKAM FDHFDFLLENSNILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGL QSNSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPA LRGEGEGLLRAIIDANKMSERIADRRKHFKQVHDEAEGTAMVMQFEHPLPESDEDEDYID TGAAILNFYCTLVDLLGRCAPDSSVIEQESPSESLGKNESLRARAILRSLVPLDDLQGVL SLRFTLHNPAAGEERPKSDMPSGLIPGHKQSIVLFLERVYGIETQELFFKLLEEAFLPDL RAATMLDRNDGYESDMALAMNRYIGNSILPLLIKHSKFYNEADNYASLLDATLHTVYRLS KNRMLTKGQREAVSDFLVALTRCLDESNFSQMQPSMLLKLLRKLTVDVSKLSEYTTVALR LLTLHYDRCAKYYGSTGGQGAYGASSDEEKRLTMVLFSNIFDSLSKMDYDPELFGKALPC LTAIGCALPPDYSLSKNYDDEWYGSKSASTQSPDGPYNPQPINTSSVVLNNDLNQIVQKF SEHYHDAWASRKLENGWTYGEQWSDINKTHPRLKPYNMLNDYERERYKEPVRESLKALLA IGWSVEHAEVDVPSTNRSSMRRSSKSQSDSASPFNYNPHPVDMTNLTLSREMQNMAERLA DNAHDIWAKKKKEELVTCGGGIHPQLVPYDLLTDKEKRKDRERSQEFLKYLQYQGYKLHK PNRGGETEVASAGASVELRFAYSLLEKLIAYLDKATINMKLLKPSDTFSRRNSFKTSTRD IKFFSKVVLPLMEKYFSTHRNYFIAVATATNNIGAASLKEKEMVAALFCKLANLLRSRLA AFGADVRITVRCLQVLVKGIDAKSLVKNCPEFIRTSMLTFFNNTADDLGHTILNLQEGKY SHLRGTHLKTSTSLSYINSVVLPVLTAMFDHLAACEYGSDLLLDEIQVASYKMLASLYTL GVDSTLTHDRKYLKTEIERNKPNLGSCLGAFSSCFPVAFLEPHLNKHNQYSLLNRIADHS LEAQDIMTKMESSMPTLETILTEVDQFVESEKTYNDAPHVVDVILPLLCSYLPFWWAQGP DNVNPTEGTYVSMVTSDHMNQLLKNVLKLIKKNIGNENAPWMTRIAAYTQQIIINSSEEL LKDPFLPLAERVRKRTDNMFHKEESLRGFIKSSTDDTSQVEAQIQEDWQLLVRDIYSFYP LLIKYVDLQRNHWLRNNIPEAEDLYNHVAAIFNIWSKSQYFLREEQNFISTNEIDNMILI MPTATRRPTTVSDGTAPAGGGKKKKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAG REQELVQHCKDRFLKKMPEYEIAEFAKTQLTLPDKIDPADEMSWQHYLYSKLGQKKDAME PVKAQQLEDVVARITDMAKVLYGLHMIDHPQQQSKSQYRSVVSIQRKRAVIACFRQTSLH SLPRHRAINIFARTYYELWLQDENVGQEVMIEDLTQSFEDAELKKMDKAEDEGKPDPLTQ LVTTFCRGAMTERSGALQEDPLYMSYAQIISKSCGEEEEEGEEEGGSGEEEGGASIHKWP HKLLMRPMHKLMEQEMEKQKLLFHQARLANRGVAEMVLLHISACKGVPSEMVMKTLELGI SILRGGNIEIQRGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGFEG AAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQNYLRTQAGNTTTVNVVICTVDYLLRLQE SIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLTEVIQGPCAQNQQALAHSRLWDA VGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTL VESAGNVELILKYFDMFLKLKDLVSSPSFLEVDLNSDGWVYPKDFKEKMEQQKSYTDEEI EFLLACCETNHDGKIDYVAFMDRFHEPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAG SVLNYFEPFLGRIEILGGNKKIERVYFEIKESNIEQWEKPQIKESKRTYFYNTVVEAGEK EKLETFINFCEDAIFEMQHASALMAVEESGGIGKARESSYTYMSEDDEERNKDPIRRGIQ AFKDGIYFFFSMFSPTNIKNKITEMQQMTIPELFIGFFKMIFYAFYYSGFGVGCVIRYFM KLLLTLMRGPHVDEPAVEVKEEEEKPSRHLPALPPTPDESNLQVQAFGMDITKEEGGQIK IAPHESSTSTPQSSIEETGESTPDEGGGEEGTRTGEGGTGESEAPVTFVDLLGGEQARAQ AAAAAEAAAAQQAAMAAVEAEAKQETAIEPSAASTIDFSEYTHRIVSFLARNFYNLKYVA LVLAFCINFMLLFYKVTSLAGDSDDEGSGDSMADILGDMSGEGSSGASGNGLEIGSGSGE NDSEEEDEDALEFVEVSEDFYYMAHVMRLMAALHSIVSLAMLVAYYHLKVPLAIFKREKE IARRVEFDGLYIAESPVEDDIKAHWDKMVISAKTFPVNYWDKFVKKKVRQKYSETYDFDY ISNLLGMEKTSFSQQEEEGSGLIHFIVNIDWRYQVWKAGVTITDNAFLYSLWYFTFSILG NYNNFFFAAHLLDVVVGFKTLRTILQSVTHNGKQLVLTVMLLTIVVYIYTVIAFNFFRKF YIQEEDDEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGEPDGDDYEVYRIMFDITFFFF VIIILLAIIQGLIIDAFGELRDQLENVKTNMESNCFICGLGKEYFDTVPHGFDTHVQQEH NLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFFPVGDCFRKQNEAVEEETKKK NT seq 15480 nt NT seq  +upstreamnt  +downstreamnt atggctgacagcgaaggtggctccgaacaggacgacgtatcattccttcgtacggaggat atggtatgtctgtcctgtacagcaacaggcgagagggtttgtctagcagccgaaggtttt ggcaatcgacactgtttcctcgaaaatatcgcagacaagaatattcctccagatctatcg caatgtgtgtttgtgatagaacaagctctctcggtgagagccttacaggaattagttacg gctgctggctctgagacgcagcaagagaatttaggaaaaggtactggatcaggacataga actttactttacggcaatgctatacttctaaggcatctaaacagcgatatgtatttggca tgtttgtcaacgagttcttcgaacgataagctcgcttttgacgtaggtttacaacaacac tctcaaggtgaagcttgttggtggacagtgcatccagcctcaaaacaaagatcagaaggt gaaaaggtccgagtaggcgacgatctaattcttgtgtcggtagctaccgagagatatttg cacacaacgaaagaaaatggtttatcagtagtgaatgcatcgtttcatgtgacacactgg tcggtacaaccttatggtactggtatcagtagaatgaaatacgtaggatatgtttttggt ggagacgttttaagattttttcatggtggcgacgagtgtcttactattccttcgacatgg aatacatcacctaatcaaaatatcgtaacttacgaaggaggaagcgttatgagccaagca agatccttgtggagattagaattagcgagaactaaatgggcaggtggttttatcaactgg ttgcatccaatgcgtataagacatttaaccactggccgatatcttggagtaaaagaaaat aacgaactatatttggtggatagaaacgaggcaacgatagaaacttctactttctggctg agacaagaaaaggatgatcaaaaaataattcttgaggataaagatttagaagttattgga atgccgattattaaatatggtgactcgacggttattatgcaacatgctacaacgtgtcta tgggtgtcttataagtcatacgaaacaaaaaagaaaggcgtgggaaaagtagaagagaag caggcggtattgcacgaagaaggaaaaatggacgatggtttagatttttcacgttctcaa gaagaagaatctagaacggcccgtgttattagaaaatgtagtagcttgttcacgcagttt attacaggcttagaaaatttgcaagttgatagaagagcatcgatgttttttcaaaatgta aatctcaatgaaatggtgatgtgtctggaagatttaatcaattactttgctcaacctgaa gacgatatggaacacgaagaaaaacaaaatagatttcgggcacttaggaatcgtcaggat ctatttcaagaagagggaatattaaatctcattttggaagctatagataaaataaatgtg attacttctcaaggctttcttgtggcactttcgggagatgaaagtggtcaagcgtgggat caaatttctggttacctttatcaattattagcagctataatcaaaggaaaccataccaat tgcgctcaatttgcaaatagcaatcgtttgaactggttgttcagccgtttaggttcgcag gcgtccagtgaaggcactggaatgctggatgtacttcactgcgttcttattgattcgccc gaagctctgaatatgatgagggatgaacatataaaagtgataatctcgcttcttgagaaa catggcagggatccaaaagttttggatgtgttatgttcgctttgcgtgggcaacggagtt gctgtacgatcatcacagaataatatctgtgattttttacttcctggaaaaaacttactt cttcagacgcaactggttgatcatgttgctagtatcagaccaaacatatttgttggtaga gtcgaaggatcagcattatatcaaaaatggtatttcgaagttacagtcgatcatatcgaa caaacaacgcatatgatgccgcatttgcggataggttgggcaaatacggctggttatatg ccatatccaggaggaggtgaaaaatggggtggaaatggtgtaggtgatgatctttactcg tttggttttgatggtgcaaatttttggacaggcggtagaaagacccaaatcgttcaaaat gctacggaaccctttatcagaaaaagcgacgtaatcggttgctccttagacttgacagtt cctgtaatatcttttaccttcaacggtacccatgttgctggcacgttcagaaactttaat ctcgatggcatgtttttcccagcgattagttgctcctcgaaactctcatgtagatttctt cttggtggcgatcatggaagattgaagtatcaaccaccagatgaattttctcctttggta gaaagtctgctaccccaacaaatactctctttggatccttgtttctattttggtaatatg aataaagtcgttttagctggaccatggttggtcgaagatgacacagcctttgttcctgcg ccggttgatacttccatgatcaatctaccaagttacgttgagcaaataagagataaactt gccgaaaacattcacgaaatgtgggcaatgaacaaaatcgaagctggatggatatacggt gaacacagagatgatttaagaaaaattcatccgtgcatagtgcagtttgagagattacca gctgcggaaaaacgatatgacactcaactcgccgtgcaaacgttgaagacaatattagct cttggatattacattacaatggataaaccaccatcaagaatcaaaactctaaggttgcct aacgaaccatttttacaaagcagtggttacaaaccagcacctttggatctcagtgctatc actttaacgcctaaaatggaggaattggtagatcaattagcagagaacacacataatctt tgggcgaaagaacgaattagtcaagggtggacttatggattgaacgaagattctgagatg agaaggagtccgcatttggtaccgtatcctaaagtagacgaggccattaagaaggctaat cgagatactgccagtgaaactgttagaacgcttcttgtatacggttatatgcttgatcca ccaactggtgaacaacacgaggctctactgttagaagctaatagattacgacaactgtac tttaggacgtatagggtggaaaaacattatgcagttaatagtggaaagtggtatttcgag tttgaagttttaacagcaggtcctatgcgtgttggttgggcaaaagctgactgtatgcca ggaagtatgttaggtagtgacgagaatacctgggcattcgatggctataatgtgacaaag gtacatgctggtacccacgaatcatttggtcacaaatatcaagtgggcgacatagttggc tgtttcattgacgtcgcagacagaactatcagtttttcattaaacggagaacttctgatg gatgcactcggaggtgaaacttcgtttgccgatgtacaaggcgattctttcgtaccagcc ttcacacttggggttggacaaaaggctaagctgacatttggtcaggacgtgaatacattg aaatttttcacgacctgcggtttgcaagaaggatacgaacccttttgtgtgaatatgaat cgtttagttacgtattggtacacgaaggatcaaccgattttcgagaatactgatgacatg gccgacactagaatagacgtcgctagaattcctgcaggatcggatactccaccgtgtttg aaaatatctcacaatacatttgaaactatggaaaaggcaaattgggaatttttaagacta tcacttcccgttatttgccagtcaatatttatctcggaaaatgataaggtacgaagatgg caagagattaagatgcatcagaacagacttttatccgaacaattcgagcagacgcaacaa gcagctccttcggctcacatggaacagatcatgaaatctggatttagtatgagcgatatc aaaggtttacaaaggaattactccgaagatgcggttgaagctgatgaaatggcgaaagag tcacctataccaatgcaaagaaataagcctacgagaccaccaagaaagggttcgatttat ggatcgcgttccggagctatggatagcgctgtaaacgaagccgaaatgaacggttacgga gagatgaacggtgacgtcaaagatgataaaaagaaacgtggccgttcgccttttagaaaa cttagcaaagaaatggaggatgtattcttctcgcgaaaagcaaaatcaccagaggccaaa gctaaaacgccggagcttcaagtacgttcggacgtatccgataagagtaccagaacgatg acaggaagtaaaacagcaagtaaaactgctcaaattcgagtttctaccaccgatttgaaa gtagtccctccacaaattcctgaacgtaacgcaccaaaaataatgtcggtattaaccggt agcggtgtagaagcgatcggtaatgaaatctttgacgcggaatgtttaaaattaatgaac gaatatttttatggtgtgagaatctttcctggtcaagatccaacacacgtttacattggt tgggtaacctcgcaatatcatttacatacaaaggactttaatttatcacgcgtaaggaaa gcttcggtcatcattacagatgattatgatcgtccgatagaacaagtcgatagacaaagt tgttacatggtaagagccgatgaattatacaacgaagttacccaagatgcatcaggaaag ggtgcatctcaagggatgtttgtcggttgcttcatagataccgcaactggttgtatttca ttcacttgcgagggtaaagaaacgagtcacaaatttaaaatggaaccagacacgaaattg ttccctgcaatttttgtggaagccaccagcaaggagatacttcaaatcgaacttggaaga acgtctacgacgttaccattatccgctgctgttttacagaactcagaacgtcacgtgata ccacaatttcctccaagattaaaagtacaatgcctgaagcctcatcaatgggccagagtt ccgaatcaatcgcttcaggtacacgctttgaaactctccgatatcagaggttggtcgatg ctttgcgaagatgctatttctatgttggctttgcatattcccgaggaagatagatgtatc gatattctcgaacttattgaaatggacaaacttttaagttttcacgcacacacattgacg ctatacgcggcattgtgttatcagtcaaactacagagcagcgcatgctttgtgccaacat gtcgatcagaaacaattattgtacgctattcgagccgaatatatgtctggaccattacga caaggtttttacgatttactgattgccttgcatctcgagtctcatgcgacaacgatggaa gtgtgtaaaaatgaatttatcatacctcttggtcaagaattgaaggatttatacgaagac gttgaaatgaaacatagtcttagatacttacaaacagaatctgtacgaccgcaaatgaaa atgactgatataaggcaaattccttctagcgatcaagttatcgagaatataagaagtcta tacagtccacactttcctctcgatgttgtacgggattatgtaatgatggcattaaacgag gccgttgaaatcaatcaagttcataatagagatccaataggtggcagtaacgaaaattta ttcttgccattgataaaactcgtggatagattacttttggttggaatgctcagaaacgaa gatgtgatgaaattactcattatgataaatccagaaacttgggacccaacatttgataaa gaaggaaaagacgagcataaaaaaggtctgcttcatatgaaaatggctgagggtgcaaag ttgcaaatgtgttatcttcttcaccatttaaacgacattcagttacgtcatcgtgttgaa tcgatcatagcattcagtcatgattttgtcggtgatttgcaatccgatcaattgcgacgt tatattgacatcaaacaatctgacttaccatctgccgtggctgctaagaagacgagagaa tttcgatgtccaccacgggaacaaatgaatgctattttaagctttaaaaatctcgatcca gaggaagatactgaaaattgtccttgcggagaagaattggtagctaaaatgaacgaattt catagcgacttaatgtcatacgtatcattgcatgctttgcaagaagctgtggatgctgct gacgaacctgtcgaggaagttcaaaaaccaggtgcaatgaagaaattatttaattttatc aatgctgtgaaagaacttgaggaagaaccaaaaccagaaccagaaccagaaaggaaaact cctgaagaggtatttcgtaaggttctgatagcaactatagtaaaatgggcggaagaagct cagattgaaacacctaaacttgttcgtgaaatgtttagtttactggttcgacaatatgat acggtaggcgaattgattagagctctggagaagacgtatgttatcaatagcaaaacgaga gaagacgttgcttcgatgtgggttggtttgagccaaattcgtgctttattgccagtacaa atgtctcaagaagaagaagaacttgtgagagagagattgtggaagctggtgaataatcat acattcttccagcatcctgatttgattcgagtacttaggattcatgagaatgtaatggca attatgatgaataccttaggtagacgtgcccaagcacaatctgatgcacagacacaggca caaactgcagaaggagaagcagccgcgaaagaaaaagatacttctcatgagatggtagtt gcttgttgtcgatttctctgttatttctgtcgcacatctaggcaaaatcaaaaggccatg ttcgatcattttgactttttattggagaacagtaatattctccttgccagaccatctttg agaggttctacaccattggatgtagcttattcctcattgatggagaacactgaattggct ctcgcgcttagggaacactatttagaaaaaatagcaatttatttgtcaagatgcggtttg caatcaaattcggagctggtcgagaagggttatcctgatcttggttgggatccagtcgag ggtgaacgttatttggactttttgaggttttgtgtatgggtaaatggtgaaagtgttgag gaaaatgcaaatttggtaatccgtttattgataagacgaccagaatgtttgggtcctgct ttacgaggtgagggagagggtttattgagagctataatagatgccaataagatgtcagaa cgtatcgccgatagacgaaaacattttaaacaggtacacgatgaggcagagggtacagca atggtgatgcagttcgaacatccacttccagaatcagacgaagatgaagattatatcgat acgggcgctgcaattcttaatttttattgcacccttgttgatttacttggtcgatgtgct ccagactcttccgtgatcgagcaagaatccccttcggagtcccttgggaagaacgaatca cttcgtgcgagagccattttacgatcattggtgccgttggatgatcttcaaggcgttcta tcattacgatttacattacacaatccagctgcgggagaagaaagaccaaaaagtgatatg ccgtctggattgatacctggtcataagcaaagcatcgtactcttcttggaacgtgtttat ggcattgaaactcaggaattgttttttaaattactcgaggaagctttcttaccagattta agagctgctaccatgttagacaggaatgatggatacgagtccgacatggctcttgccatg aatcgatatataggaaacagcatcttgcccttgctgataaaacattcaaagttttacaac gaagctgataattatgcgagtttattggacgctactttacatactgtatatcggttgagc aaaaatagaatgttaacgaagggtcaacgtgaagctgtctcagacttcctcgttgcttta accagatgtcttgacgagtcaaatttttcccaaatgcaaccgagtatgttacttaaacta cttcgaaaattaacagtggatgtttctaaactatctgaatacaccacggtcgctttaagg ttgcttactttgcattacgatcgttgcgcgaaatattatggatctaccggaggccaagga gcttatggtgcttcgagcgatgaagaaaaacgtttgacgatggttttgttcagcaatata ttcgattccttgtccaaaatggattacgatccggaattgtttgggaaggctttaccctgt ctcactgctataggttgcgctttaccaccggattattcattgtcgaaaaattatgatgat gaatggtatggtagtaaatcagcatccacgcaatcacctgacggtccatataatccacaa cctatcaatacatctagcgtcgttctcaacaatgatctgaatcaaatagtacaaaaattc tccgagcattatcacgatgcatgggctagtcgaaaattagagaatggttggacatatggt gaacaatggtccgatataaataaaactcatccgagattgaaaccgtataatatgttaaac gattacgagagagaacgttacaaagaaccagttcgagaaagtttgaaagctcttttggct attggctggagcgttgaacatgccgaagttgatgtaccttcaacgaatcgtagttctatg agaagatcatccaaaagtcagagcgattctgcaagtccatttaattacaatccccatcca gtcgatatgaccaatttgacgttaagcagagaaatgcaaaacatggccgaacgtttagcc gataatgctcatgatatttgggctaaaaagaaaaaggaagaacttgtcacgtgcggaggt ggtattcatcctcaattggtaccttatgatctattaactgataaggaaaagcgaaaggat cgtgaacgttctcaagaattcttaaaatatttgcaatatcaaggctacaaacttcacaag ccaaatcgtggaggagaaacagaagttgccagtgccggtgcatcagttgaattacgtttt gcttattccttattagaaaagctgatagcgtatcttgacaaagcaacgattaacatgaaa ctcctcaaaccatctgatacgtttagtcgtaggaacagctttaaaacgtcgacaagagac ataaaatttttcagcaaagtggtgttgccattgatggaaaaatattttagtactcacagg aattactttatcgcagtggcaacagctacgaataatattggggcagcctcgttgaaggag aaagaaatggtcgcagcacttttttgcaaattagcaaatttgttacgatccagacttgct gcttttggtgctgacgtaaggataacagtacgttgtctgcaggtccttgtaaagggtatc gacgcaaagagtcttgtgaaaaattgtccagaatttatcaggacttctatgttgactttt ttcaataacacagcggacgatttaggtcatacgatattaaatcttcaagagggtaaatat agtcaccttagaggtactcatctgaaaacttcaacatccttatcgtacatcaacagcgtt gtattgcccgttctcacggccatgttcgaccatcttgctgcttgcgaatacggaagcgat ttgttgttggatgaaattcaagtagcctcttacaagatgttggcatctctttatactctc ggtgtagattctaccctaacgcacgataggaaatacctaaaaaccgaaatcgaacgtaac aaaccaaatctcggttcctgcttgggtgccttttcaagttgtttcccagttgcctttcta gaacctcatttaaacaaacataatcaatattctcttctaaaccgtattgccgatcattcg 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gagatcgccgaatttgctaagacccaattaactttaccggacaaaatcgaccccgcggac gagatgtcttggcagcattatttgtattcgaagttaggacagaagaaggatgcaatggaa ccagttaaagctcaacaattggaagatgtagttgctagaattacagacatggctaaagta ctttacggcctacatatgatagatcatccacaacagcagagcaagagtcaataccgatcc gtggtgtcgatacaacgcaaacgagcggtgatagcttgtttccgtcaaacttccctacat tccttgcccaggcatcgggcaataaatatatttgcaaggacatattacgaattgtggttg caggatgaaaacgtaggtcaggaagtaatgattgaagaccttacgcaatcttttgaggat gcagaattgaagaaaatggacaaggccgaggacgagggtaaaccagatccattaacgcaa ttggttacgacgttctgtcgtggtgctatgactgaaagatccggtgctcttcaagaagat ccattgtacatgagttacgctcagattatatcgaaatcttgcggcgaagaagaagaagag ggtgaagaggaagggggaagtggtgaagaagaaggcggagcatctattcataagtggcca cataaactgcttatgaggccaatgcataaattaatggaacaagaaatggagaagcagaag ctgctctttcatcaagcacgtttagcgaatcgtggtgtcgcagagatggtgttgcttcat atatcagcttgcaaaggtgttccaagcgagatggttatgaaaacgttggaattgggaatt tctattttacgcggtggtaacatcgagatacaacgaggaatgttaaatcatctgaaggag aagaaagacgtcggttttttcacttcaatcgcgggtcttatgaattcctgtagtgtccta gatttggatgctttcgagagaaacacgaaagccgaaggtcttggtgttggttttgaaggt gctgctggtgaaaagaatatgcacgatgctgaattcacatgtgcattgttccgtttcata caactgacttgtgaaggccataatcttgattggcaaaattatcttagaacgcaagcgggt aatacaacaacggtaaatgtcgtcatatgtactgtggattatttactgcgcttacaagaa tccattatggatttttattggcattattcgagtaaagaactgattgatcctgctggtaaa gcgaacttcttcaaagctataggtgttgctagtcaagtcttcaatacccttactgaagtt attcaaggaccttgcgcacaaaatcaacaggccttagcacattccagattgtgggatgct gttggtggttttctctttttgttttcacatatgcaagataaattatctaaacactccagt caagtagatctcttgaaagaattattaaatctacaaaaggatatgatcactatgatgctg tcaatgttggaaggaaatgtcgtgaatggtactatcggaaaacagatggttgacaccttg gtcgagtcggctggaaacgtcgaattgattttgaaatatttcgatatgttcctgaaattg aaagatctagtatcatcgccaagtttcttagaagtagatcttaatagcgatggttgggta tatcctaaagattttaaagagaaaatggagcaacaaaaaagttataccgacgaagagatt gagtttctattagcttgctgcgagacgaatcatgatggtaagatcgactacgtcgctttt atggatcgtttccacgaacctgcaaaagaaatcggcttcaatctcgcagtacttctcacc aatctttcggagcatatgcctaatgagcctagattagcgagattccttgaaactgctggc tccgttctcaattatttcgaaccctttcttggaagaatcgagattctaggtggtaataaa aagatcgagcgtgtttatttcgaaataaaagaatcaaatatagaacagtgggagaagcca caaattaaagaatcaaaaagaacatatttttataacacggtagtcgaggccggtgaaaaa gaaaagctggaaacttttattaatttctgcgaagatgcgatatttgaaatgcaacatgcc agtgctttgatggctgtagaagaaagcggcggtattggtaaagcaagagaatcatcctat acttatatgtcggaagatgatgaagaaagaaacaaagatccgataaggagaggtatacaa gctttcaaggatggcatttatttctttttctccatgttttcaccaacgaatataaagaat aaaataacagaaatgcaacagatgacaatacccgaactatttattggctttttcaaaatg atattctacgcattttattattctggattcggagttggttgtgttatcaggtactttatg aaattattattaactttgatgagaggaccacatgtggacgaacctgcggtcgaggtgaaa gaagaggaagaaaaaccatcaagacatttaccggctctacctccaacgccagatgaatct aatttacaggtacaagctttcggaatggatataacgaaagaggaaggtggtcaaataaag atagcaccgcacgaatcgtcaacttcgacaccacaatcgagcatcgaggaaactggcgaa agtaccccagacgaaggtggtggtgaagaaggtacaagaacgggcgaaggtggtactgga gaatctgaagcacctgttacattcgttgatttacttggtggcgaacaggcaagagctcag gccgcagcagcagctgaggccgcggcagctcaacaagcagcaatggcagcagtagaggca gaagcaaaacaagaaacagcaatcgaaccatcggctgcttcgaccatagatttctctgaa tatactcaccgcattgtctcatttttggctagaaatttctataatctgaaatatgttgct cttgttcttgccttctgtataaacttcatgctactattctataaggttacatctctcgct ggtgattcggacgatgaaggcagtggcgattctatggctgatatcttaggtgacatgtca ggtgaaggttcatcgggtgcaagcggtaacggtttagaaatcggaagtggtagtggtgaa aatgattcggaagaggaagatgaagatgctttagaattcgttgaagtatcagaagacttt tattatatggctcacgttatgagacttatggctgctcttcattctatcgtctcgttagct atgctggtcgcttattatcatcttaaagtaccgttagccatatttaaacgtgaaaaagaa atcgcacgtcgagttgaattcgatggtctgtacatagctgaaagtcccgtagaagatgac ataaaggcacattgggataaaatggtaatatcggccaaaacgttccctgttaattattgg gataaattcgtcaaaaaaaaagtaagacaaaagtacagtgaaacttatgatttcgactac atcagcaatttgcttggaatggaaaagacatctttcagtcaacaagaagaagaaggttct ggcttgatacactttatcgtaaatatcgattggagatatcaagtatggaaagctggcgtc actatcacagataatgcatttctgtacagtctttggtacttcacattttcaattttggga aattacaataactttttctttgctgcacatttacttgacgttgtggttggtttcaaaaca ttgagaacgatcttacaatctgtaacgcacaacggaaaacaattggtgctaacagtaatg ttattaacaatcgtagtctacatttataccgtgatagccttcaatttctttagaaaattt tatattcaagaggaggacgacgaagttgataagaaatgtcacgacatgttaacgtgtttc gtttttcatttgtacaaaggtgtaagagccggtggtggtatcggtgacgaaattggagaa ccagatggtgatgattatgaagtttatcgtatcatgtttgatatcacatttttcttcttt gtcatcattattcttcttgctattatccaaggtttgatcatcgatgcgtttggtgagctt cgagaccaactcgaaaacgtcaaaacgaatatggagagcaattgcttcatatgtggttta ggaaaggaatattttgatacggtaccacacggattcgacactcatgttcaacaagaacac aatctcgcaaattatatgttcttcctgatgcatctaatcaacaaacccgatacagagtac acgggtcaagaaacgtacgtctggaatatgtaccaacaaagatgttgggacttcttccct gtcggtgattgcttccgtaaacagaacgaagcggtagaagaagaaactaaaaagaaataa

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