KEGG T01084: 100245451

Vitis vinifera (wine grape): 100245451

Entry

100245451         CDS       T01084

Name

(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha 1, mitochondrial

K00166

2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]

Organism

vvi Vitis vinifera (wine grape)

Pathway

vvi00280

Valine, leucine and isoleucine degradation

vvi00640

Propanoate metabolism

vvi00785

Lipoic acid metabolism

vvi01100

Metabolic pathways

vvi01110

Biosynthesis of secondary metabolites

vvi01210

2-Oxocarboxylic acid metabolism

Module

vvi_M00036

Leucine degradation, leucine => acetoacetate + acetyl-CoA

Brite

KEGG Orthology (KO) [BR:vvi00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    100245451
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    100245451
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    100245451
Enzymes [BR:vvi01000]
1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     100245451

SSDB

Motif

Pfam:

E1_dh TPP_enzyme_C DXP_synthase_N

Other DBs

NCBI-GeneID:

100245451

NCBI-ProteinID:

XP_002268860

UniProt:

E0CQJ8

LinkDB

Position

18:join(12928047..12928277,12930082..12930219,12930362..12930544,12930606..12930763,12930843..12930942,12931033..12931144,12931311..12931450,12931564..12931749,12931856..12932023)

AA seq 471 aa
MAAWFTRSGNIAHHVKRNMGSFLRPAPTLSDSSWSRSPACLGNSPALLWAGRLESTRAQK
LVDSDSENDAPLRDDDQAIDFPGGRVMLTSEMQFIPGYPQQRVHCYHLMNNDGQTNMCSS
FEQVSKEVAVKMYSDMITLQIMDTIFYEAQRQGRISFYLTSVGEEAINIASAAALSPDDI
VMAQYREPGVLLWRGFTLQEFANQCFGNKADCGKGRQMPIHYGSKKLNYFTVSSPLATQL
PQAVGAAYSLKMDNKDACVVAYFGDGSTSEGDFHASLNFAAVMEAPVIFLCRNNGWAIST
PTSEQFRSDGIVVKGPAYGIQSIRVDGNDALAVHNAVRAARQMAIHEQRPILVEALTYRV
GHHSTSDDSTKYRPVDEVKHWEMGQNPVNRFRKWVERNGWWSEEDESQLRSSIRKQLLQA
IQVAEKMEKPPLADLFSDVYDVPPSILFEQEQQLRETIKRHPQDYPSDVPV

NT seq 1416 nt +upstreamnt +downstreamnt
atggcggcctggttcacaaggtctggaaacattgcccaccatgtcaagagaaacatgggc
tccttcctccgaccagctccgactctgagcgactcttcttggagtcgttcacccgcatgc
ctcggaaactcccccgccctgctctgggctgggcgtttggaatccactagagctcagaaa
cttgttgattcagattctgagaatgatgcccccctccgagatgatgatcaggccatagat
tttccaggagggagggtgatgcttacttctgaaatgcaatttatcccaggttaccctcaa
cagagggtccactgttatcatcttatgaataacgacggccaaacaaatatgtgcagcagt
tttgaacaggtaagcaaggaagttgcagtgaagatgtacagcgacatgatcacccttcaa
ataatggacaccatcttctatgaagcacagaggcaaggaagaatttccttttatctcaca
tcagttggagaagaagccatcaacattgcatctgcagctgcactctctccagatgatatt
gtcatggcacagtaccgggagcctggagttctgctgtggcgtggtttcacactgcaagaa
tttgccaaccagtgtttcggaaacaaggctgattgtggcaaaggcaggcagatgcccatc
cattatgggtctaagaagctcaactacttcactgtgtcatcgccccttgccacacaactt
ccccaagccgtgggtgctgcttattcacttaaaatggataacaaggatgcatgtgtagtg
gcatactttggggatggtagcaccagtgagggtgatttccatgccagtctaaattttgct
gctgtgatggaagctcctgttatttttctgtgtcgcaacaatggatgggccatcagtacc
cctacatcagaacagtttcgaagtgatggcattgttgtcaagggtccggcgtatggaatc
caaagcatcagggtagatgggaatgatgctctagctgttcataacgcagttcgtgcggct
cgtcaaatggcgattcacgaacagaggcctatactagttgaggcccttacatatcgggta
ggacaccactctacatcggatgactccaccaagtatcggccggttgatgaggttaagcac
tgggaaatgggtcaaaaccctgtaaatagattcagaaaatgggttgaaaggaatgggtgg
tggagcgaggaagatgagtctcagctccggagcagcatcaggaagcagctactgcaagca
attcaagttgcagaaaaaatggagaaacccccacttgcagacttgttcagtgatgtttat
gatgttccaccatcgatcctcttcgagcaggaacagcagcttagagaaactatcaagagg
cacccacaagactatccctctgatgttcctgtttag

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