Vulpes vulpes (red fox): 112917764 Help Entry 112917764         CDS       T05911                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism vvp  Vulpes vulpes (red fox) Pathway vvp01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:vvp00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     112917764 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:vvp03032]     112917764 (TOP2A)    03036 Chromosome and associated proteins [BR:vvp03036]     112917764 (TOP2A) Enzymes [BR:vvp01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      112917764 (TOP2A) DNA replication proteins [BR:vvp03032]  Eukaryotic type   DNA Topoisomerases    112917764 (TOP2A) Chromosome and associated proteins [BR:vvp03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     112917764 (TOP2A)   Centrosome formation proteins    Centriole proteins     112917764 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  112917764 NCBI-ProteinID:  XP_025851509 UniProt:  A0A3Q7S0E5 LinkDB All DBs Position Unknown AA seq 1519 aa AA seqDB search MQISKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQIWVYDEDIGMNY REVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKV EKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQ TWMDNMGRAGEMELRPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKD VKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVCLTMSEKGFQQIS FVNSIATSKGGRHVDYIADQIVTKLVDVVKKKNKGGVAVKAHQVKSHMWIFVNALIENPT FDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQIQLNKKCSAVKH NRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILN VREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGL LINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKY YKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQTDDRKEWLTHFMEDR RQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFT CFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGT RLHGGKDSASPRYIFTMLSPLARLLFPPKDDQTLKFLYDDNQRVEPEWYIPIIPMVLING AEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGE VAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKM TEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGL RKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKE AQQKVPDEEENEESDNENEAEKSDSVRDSGPTFNYLLDMPLWYLTKEKKDELCKLRNEKE QELETLKRKSPTDLWKEDLATFVEELEAVETKEKQEEQIGLPGKGGKGKGKKTQMAEVLP SPCGKRVIPRVTIEMKAEAEKKIKKKIKNENTEGSPQEESIEIEGLKQRLEKKQKREPGT KTKQTTLPFKPIKKGKKRNPWSDSESDMSSNESNFDVPPREVEPRRAATKKKFTVDLDLD NSFSDFEERIQDEDSVPSDVSPHKTKASPKRTAKELKPQKSAPSVMDLDADDAKDSVPLS PGSTADFSAETEIVNPLPKKKVAVKKIAPKSQSSTSTTGAKKGAAPKGTKKDPGLNSDVS QKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTATNKKSKGESEDFHLDLDSAVAPRAKS GRARKPIKYLEESDEDDLF NT seq 4560 nt NT seq  +upstreamnt  +downstreamnt atgcaaatcagcaaaacaaagaaaaatgaagatgctaagaaaagactgtctattgaaagg atctatcaaaagaaaacccaactggaacatattttgctccgcccggacacctacattggc tctgtggaattagtgacccagcaaatatgggtttacgatgaagatattggcatgaactat agagaagttacctttgtccctgggttgtacaaaatctttgatgagattctggtcaatgct gcagacaacaaacaaagggacccaaaaatgtcttgtattagagtcacaattgacccggaa aacaatttaattagtatatggaataatgggaaaggtattcctgttgttgaacacaaagtt gagaagatgtatgtcccagcactcatctttggacagctcctaacttctagtaactatgat gatgatgaaaagaaagtaacaggtggtcgaaatggctatggggccaaattgtgtaacata ttcagtacgaagtttactgtggaaacagccagtagagaatacaagaaaatgttcaaacag acatggatggataacatgggaagggctggtgagatggaactcaggccatttaatggggaa gattatacatgtattaccttccagcctgacttgtccaagtttaaaatgcaaagcctagat aaagacattgttgcactgatggttagaagagcatacgatattgctggatccactaaagat gtcaaagtctttctcaatggaaataaactaccggtaaaaggattccgtagctatgtagat atgtatctgaaggataaggtagatgaaactggcaatccattgaaaattatccatgaacaa gtaaaccccaggtgggaagtatgtttaacaatgagtgaaaaaggctttcagcaaattagc ttcgtcaacagcattgctacctccaagggtggcagacatgttgattatatagctgatcag attgtgactaaacttgttgatgttgtgaagaagaagaacaagggtggtgttgcagtaaaa gcacatcaggtgaaaagtcacatgtggatttttgtgaatgccttgattgaaaacccaacc tttgactctcagacaaaagaaaacatgactttacaagtcaagagctttggatcgacatgc caattaagtgaaaaattcatcaaagctgcaactggctgtggtattgtggaaagcattcta aactgggtaaagtttaaggcccaaatccaattaaacaagaagtgttcagctgtaaaacat aacagaatcaagggaattcccaaacttgatgatgccaatgatgcagggggtcgaaactcc aatgagtgtacacttatcctgactgagggagactcggctaaaactttggctgtttcaggc cttggtgtggttgggagagacaaatatggagttttcccgcttagaggaaaaatactcaat gttcgagaagcttctcataaacagatcatggaaaatgctgaaattaataatatcatcaag atcgtgggtcttcagtacaagaaaaactatgaagatgaagattcattgaagactcttcgt tatgggaagataatgattatgacagatcaggaccaagatggttcccatatcaaaggcttg ctgattaattttatccatcataactggccctctcttctacggcatcgttttctggaggaa tttatcactccgattgtaaaggtgtctaaaaacaaacaagaaatggcattctatagcctt cctgaatttgaagaatggaagagttctactccaaatcataaaaaatggaaagtcaagtac tacaaaggtttgggtaccagcacatcaaaagaagctaaagaatactttgcagatatgaaa agacatcgtattcagttcaaatactctggtcctgaagatgatgctgccatcagcttggcc tttagcaagaaacagacagatgatcgaaaggaatggttaactcatttcatggaagataga agacaacggaagttacttggccttcctgaggattacttgtatgggcaaactaccacatat ctgacatacaatgactttataaataaggaacttatcctgttctcaaattctgataacgag agatctatcccatctatggtggatggcttgaaaccaggtcaaagaaaggttttgtttacc tgtttcaaacggaatgacaagcgagaggtgaaggttgcccagttggctgggtcagtggct gagatgtcctcttatcatcatggtgagatgtcactaatgatgaccattataaatttggct cagaattttgtgggtagcaataatctgaacctcttgcagcccattggtcagtttggtact aggctgcacggtggcaaggattctgctagtcctcgatacatcttcacaatgctcagccct ttggctcggttattgtttccaccaaaagatgatcagactttaaagtttttatatgatgac aatcaacgtgttgaacctgaatggtacattcccattatacccatggtgctgataaatggt gctgaaggaattggtactgggtggtcctgcaaaatccccaactttgatattcgtgaagtt gtaaataatatcaggcgtttgatggatggagaagaacctttgccaatgcttccaagttac aagaacttcaagggtactattgaagagctggctccaaatcagtatgtgattagtggtgaa gtggctatacttaattccacaaccattgaaatttcagagcttcctgtcagaacatggacc cagacctataaagaacaggttctagaacccatgttgaatggcactgagaagacaccacct ctcataacagattatagggagtaccatacagacaccactgtgaagtttgttgtgaagatg actgaagagaaactggcagaggcagagagagtggggctacacaaagtcttcaaactccaa actagtctcacatgcaactccatggtgctttttgaccatgtaggttgtttaaagaaatat gacacagtgttggatattctaagagacttctttgaactaaggcttaaatattatggatta agaaaagaatggcttctaggaatgcttggcgctgaatctgctaaactgaacaatcaggct cgctttatcttagagaaaatagatggcaaaataattattgaaaataagcctaagaaagaa ttaattaaagttctgattcagaggggatatgattcggatcctgtgaaggcttggaaagaa gctcagcaaaaggtaccagatgaagaagagaatgaagagagtgacaatgaaaatgaagct gaaaagagtgactctgtaagagattctggaccaaccttcaactaccttcttgatatgcct ctttggtatctcaccaaggagaagaaggatgaactgtgcaagctgagaaatgaaaaagag caagaactagaaacattaaagagaaagagtccaacagatctgtggaaagaagacttggct acttttgttgaagagctggaggctgttgaaacaaaggaaaaacaagaagaacaaatagga cttccagggaaaggagggaaaggaaaggggaaaaaaacacaaatggctgaagttttgcct tctccttgcgggaaaagagtcatcccccgagtgaccatagagatgaaagcagaggcagaa aagaaaattaaaaagaaaattaagaatgaaaacactgaagggagccctcaagaagagagt atcgaaatagaaggtctgaaacaaaggttggagaagaaacagaaaagagaaccaggtacc aagacgaagcaaactacattgccgtttaaacccatcaaaaaaggaaagaagagaaacccc tggtctgattcagaatcagatatgagcagtaatgaaagtaactttgatgtccctccacga gaggtagagccacggagagcagcaacaaaaaagaaattcacagtggatttggatttagac aacagtttctcagattttgaagaaagaattcaagatgaggattctgttccatcagatgtc agcccacataagaccaaagcttccccaaaacgtactgccaaagaactgaagccacagaaa agtgccccctcagtaatggaccttgatgctgacgatgccaaggacagtgtaccactttct ccaggttctactgctgatttctcggctgaaactgaaattgtaaacccccttcctaaaaag aaggtggccgtgaagaagatagcaccaaaaagtcagtcttccacctccactacaggtgca aaaaaaggggctgcaccaaaaggaaccaaaaaggatccaggcttaaattctgatgtctct caaaagcctgatcccccaaaaacgaaaaatcgccgcaaaaggaagccatccacttctgat gattccgactctaattttgagaagatgatttctaaaacagccacaaacaagaaatccaag ggggagagtgaagacttccatctggacctagactcagctgtggctcctcgggccaaatct ggacgtgcaaggaaacctataaagtacctcgaagaatcagatgaagatgatctgttctaa

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