Vulpes vulpes (red fox): 112921089 Help Entry 112921089         CDS       T05911                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism vvp  Vulpes vulpes (red fox) Pathway vvp00230   Purine metabolism vvp01100   Metabolic pathways vvp01522   Endocrine resistance vvp04015   Rap1 signaling pathway vvp04022   cGMP-PKG signaling pathway vvp04024   cAMP signaling pathway vvp04062   Chemokine signaling pathway vvp04072   Phospholipase D signaling pathway vvp04081   Hormone signaling vvp04082   Neuroactive ligand signaling vvp04114   Oocyte meiosis vvp04211   Longevity regulating pathway vvp04213   Longevity regulating pathway - multiple species vvp04261   Adrenergic signaling in cardiomyocytes vvp04270   Vascular smooth muscle contraction vvp04371   Apelin signaling pathway vvp04540   Gap junction vvp04611   Platelet activation vvp04713   Circadian entrainment vvp04714   Thermogenesis vvp04723   Retrograde endocannabinoid signaling vvp04724   Glutamatergic synapse vvp04725   Cholinergic synapse vvp04727   GABAergic synapse vvp04742   Taste transduction vvp04750   Inflammatory mediator regulation of TRP channels vvp04911   Insulin secretion vvp04912   GnRH signaling pathway vvp04913   Ovarian steroidogenesis vvp04914   Progesterone-mediated oocyte maturation vvp04915   Estrogen signaling pathway vvp04916   Melanogenesis vvp04918   Thyroid hormone synthesis vvp04921   Oxytocin signaling pathway vvp04923   Regulation of lipolysis in adipocytes vvp04924   Renin secretion vvp04925   Aldosterone synthesis and secretion vvp04926   Relaxin signaling pathway vvp04927   Cortisol synthesis and secretion vvp04928   Parathyroid hormone synthesis, secretion and action vvp04934   Cushing syndrome vvp04935   Growth hormone synthesis, secretion and action vvp04961   Endocrine and other factor-regulated calcium reabsorption vvp04962   Vasopressin-regulated water reabsorption vvp04970   Salivary secretion vvp04971   Gastric acid secretion vvp04972   Pancreatic secretion vvp04976   Bile secretion vvp05032   Morphine addiction vvp05163   Human cytomegalovirus infection vvp05166   Human T-cell leukemia virus 1 infection vvp05200   Pathways in cancer vvp05207   Chemical carcinogenesis - receptor activation vvp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:vvp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112921089 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112921089 (ADCY6)    04371 Apelin signaling pathway     112921089 (ADCY6)    04072 Phospholipase D signaling pathway     112921089 (ADCY6)    04024 cAMP signaling pathway     112921089 (ADCY6)    04022 cGMP-PKG signaling pathway     112921089 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112921089 (ADCY6)    04081 Hormone signaling     112921089 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112921089 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     112921089 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112921089 (ADCY6)    04062 Chemokine signaling pathway     112921089 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     112921089 (ADCY6)    04923 Regulation of lipolysis in adipocytes     112921089 (ADCY6)    04912 GnRH signaling pathway     112921089 (ADCY6)    04913 Ovarian steroidogenesis     112921089 (ADCY6)    04915 Estrogen signaling pathway     112921089 (ADCY6)    04914 Progesterone-mediated oocyte maturation     112921089 (ADCY6)    04921 Oxytocin signaling pathway     112921089 (ADCY6)    04926 Relaxin signaling pathway     112921089 (ADCY6)    04935 Growth hormone synthesis, secretion and action     112921089 (ADCY6)    04918 Thyroid hormone synthesis     112921089 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     112921089 (ADCY6)    04916 Melanogenesis     112921089 (ADCY6)    04924 Renin secretion     112921089 (ADCY6)    04925 Aldosterone synthesis and secretion     112921089 (ADCY6)    04927 Cortisol synthesis and secretion     112921089 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112921089 (ADCY6)    04270 Vascular smooth muscle contraction     112921089 (ADCY6)   09154 Digestive system    04970 Salivary secretion     112921089 (ADCY6)    04971 Gastric acid secretion     112921089 (ADCY6)    04972 Pancreatic secretion     112921089 (ADCY6)    04976 Bile secretion     112921089 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     112921089 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     112921089 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     112921089 (ADCY6)    04727 GABAergic synapse     112921089 (ADCY6)    04725 Cholinergic synapse     112921089 (ADCY6)    04723 Retrograde endocannabinoid signaling     112921089 (ADCY6)   09157 Sensory system    04742 Taste transduction     112921089 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     112921089 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     112921089 (ADCY6)    04213 Longevity regulating pathway - multiple species     112921089 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     112921089 (ADCY6)    04714 Thermogenesis     112921089 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112921089 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     112921089 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112921089 (ADCY6)    05163 Human cytomegalovirus infection     112921089 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     112921089 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112921089 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112921089 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112921089 (ADCY6) Enzymes [BR:vvp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112921089 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  112921089 NCBI-ProteinID:  XP_025856001 UniProt:  A0A3Q7SKN7 LinkDB All DBs Position Unknown AA seq 1168 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRRGTRTSGFCTPRYMSCLRDAQPPSPTPAAAA PPRCPWQDEAFIRRGGPGKGTELGLRAVALGFEDTEAMSAVGAAEVAPDVTPGSRRSCWR RLAQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAY VALLACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSVGLW CPVFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFLCTN VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR QMGIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKK YSRKVDPRFGAYVACALLVFCFICFIQLLVFPHSTVMLGIYASIFVLLLITVLTCAVYSC GSLFPKALRRLSRSIVRSRAHSTVVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNVT PADITACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHISSIGKLA MIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNDTFDGLDCPAAGRVALKYMTPV ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS EERFRQLEKIKTIGSTYMAASGLNASTYDQAGRSHITALADYAMRLMEQMKHINEHSFNN FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG YQLECRGVVKVKGKGEMTTYFLNGGPPS NT seq 3507 nt NT seq  +upstreamnt  +downstreamnt atgtcgtggtttagtggcctcctggtccccaaagtggacgaacggaagacagcctggggt gaacgcaatgggcagaagcgtccacgccgcgggactcggaccagtggcttctgcacgccc cgctacatgagctgcctccgggacgcgcagccccccagtcccacccctgcggctgcggct ccgccgcggtgcccctggcaggatgaggccttcatccggagaggcggcccgggcaagggc acggagctggggctgcgggcggtggccctgggcttcgaggacactgaggccatgtcagcg gttggggcagctgaggtggcccctgacgtgacccccgggagtaggcgatcctgctggcgc cgtctggcccaggtgttccagtccaagcagttccgctcggccaagctggagcgcctgtac cagcggtacttctttcagatgaaccagagcagcctgacgctgctgatggcggtgctggtg ctgctgacggcggtgctgctggccttccatgctgcgcctgcccgccctcagcctgcctac gtggccctgctggcctgtgccgccaccctcttcgtggcgctcatggtggtgtgtaaccgg cacagctttcgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggca gccgttcaggttgggggcgccctggcagccaacccccgcagcccctctgtgggcctctgg tgccctgtgttttttgtctacatcacctacacgctcctacccatccgcatgcgggcagct gtcttcagtggcctgggcctgtccaccctgcatttgatcttggcctggcaactcaaccgc ggtgacgccttcctctggaagcagctcggtgccaacatgctgctgttcctctgcaccaac gtcattggcatctgcacacactacccagctgaggtctctcagcgccaggcctttcaggag acccgcggttacattcaggcccggctgcacctgcagcacgagaaccggcagcaggaacgg ctgctgctgtccgtgttgccccagcatgttgccatggagatgaaagaagatatcaacaca aagaaagaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatc ctgtttgcagacattgaaggctttaccagcctggcgtcccagtgcaccgcgcaggagctg gtcatgaccctgaacgagctctttgcccggtttgacaagctggctgcggaaaatcactgc ctgaggatcaagatcttaggggactgttactactgtgtgtcggggctgccggaggcccgg gcagaccatgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcgctg gtgcgtgaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagcgggcgtgtg cactgtggcgtccttggcctgcggaaatggcagttcgatgtgtggtccaatgacgtgact ctggccaaccacatggaggcggggggccgggccggccgcatccacatcacccgggccacg ctgcagtacctgaacggggactacgaggtggagccgggccgcggtggcgagcggaacgcg tacctcaaggagcagcacatcgagaccttcctcatcctgggagccagccagaaacggaaa gaggagaaggccatgctggccaagctgcagcggacgcgggccaactccatggaaggcctg atgccacgctgggtgcccgaccgcgccttctcccggaccaaggactccaaggctttccgc cagatgggcattgatgattccagcaaagacaaccggggtgcccaagatgccctgaacccc gaggatgaggtcgatgagttcctgggccgtgccatcgatgcccgcagcatcgatcagcta cggaaggaccacgtgcgccgcttcctgctcaccttccagagagaggatcttgaaaagaag tactcgaggaaggtggacccccgcttcggagcctacgtggcttgtgcgctgttggtcttc tgcttcatctgctttatccagctcctcgtcttcccacactcaaccgtgatgcttgggatc tacgccagtatctttgtgctgctgctgatcaccgtgctgacctgtgccgtgtactcctgt ggctctctcttccccaaggccctgcgacgtctttcccgcagcatcgtccgctctcgggcg cacagcactgtggttggcattttttcagtcttgctagtgttcacctctgccatcgccaac atgttcacctgtaaccacacccccatccggacctgtgcagcccggatgctgaatgtaaca cccgctgacatcaccgcctgccacctgcagcagctcaattactctctgggcctggatgct ccgctgtgtgagggcaccgcacccacttgcagcttccctgagtacttcgttgggaacatg ctgctgagtctcttggccagctctgtcttcctgcacatcagtagcatcgggaagttggcc atgatctttgtcctggggctcatctatttggtgctgcttctgctgggccccccagccacc atctttgacaactatgacctgctgcttggtgtccatggcttggcttcttccaatgacacc tttgatgggctggactgcccagctgcggggagggtggcacttaaatacatgacccctgtg attctgctggtgtttgccctggcgctgtatctgcacgcccagcaggtggaatcaactgca cgtctggacttcctctggaaactgcaggcaacgggggagaaggaggagatggaggagctc caggcctacaaccgaaggctgctgcataacattctgcctaaggacgtggctgcccacttc ctggcccgggagcgccggaacgatgagctctactaccagtcgtgtgagtgtgtggccgtc atgtttgcctccattgccaacttttctgagttctatgtggagctggaggcaaacaatgag ggtgtcgagtgcctgcggctgctcaacgaaatcatcgctgactttgatgagatcatcagc gaggagcggttccggcagctggagaaaatcaagacgatcggtagcacgtacatggctgcg tcggggctgaacgccagcacctacgatcaggccggccgctcccacatcactgccctggcc gactatgccatgcggctcatggagcagatgaaacacatcaacgagcactccttcaacaac ttccagatgaagattgggctgaacatgggcccagttgtggcaggcgtcattggggctcgg aagccacagtatgacatctgggggaacacggtgaatgtctctagccgtatggacagcacg ggggttcctgaccgaatccaggtgaccacggacttgtaccaggttctagctgccaaaggc taccagctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctac ttcctcaatgggggcccccccagttag

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