Wolbachia endosymbiont of Drosophila simulans wHa: wHa_09460
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Entry
wHa_09460 CDS
T02640
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
wen
Wolbachia endosymbiont of Drosophila simulans wHa
Pathway
wen00300
Lysine biosynthesis
wen00550
Peptidoglycan biosynthesis
wen01100
Metabolic pathways
wen01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
wen00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
wHa_09460 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
wHa_09460 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
wHa_09460 (murF)
Enzymes [BR:
wen01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
wHa_09460 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGK00361
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Position
1106816..1108345
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AA seq
509 aa
AA seq
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MFKWNTNNIIDATGGRDVNGCNWIHSSNISTDTRSIKKGDLFIALKGRNFDGHNFLHEAF
LKGAVAAIVSEGKYKNFPLIIVQDTLKALHDMASYYIRNVLIDAKVIAVTGSVGKTTTKD
MLHTVLSQYGVSHANEGNLNNNIGLPLTILKAPKNCQYLILEMGMNKAGEIKELSKISNP
NIAVITNIEPAHTENFSSLFDVAQAKLEILYGMKNNGTLVLSRDNKYYDYLSSHANRNVI
SFGKDKNAEVCLLNLIRNDESSVISALSSVIPVLDYLDPGSSIANEHIRRLYNKDWIPAS
RAGMTSNRVANRLSLKIRLSDNQIINCNLRVQGEHFAYSLLAVAAVVQSLGLDLSKLPLA
LKNFSVAKGRGNIHKIKYNRKYIHLIDDSYNASPASMKTAIKTLSTYSNQRKVALLGDML
ELGDESIEFHTDLVKIITENNIDKVYTVGKFMLELHELLPDNIRGTHFNDSNQLKSDLAN
IIQNNDAILVKGSRGMKMDLIVREFVIKY
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgtttaaatggaacacaaataatatcattgatgcaactggcggaagagacgtaaatggt
tgtaattggatacatagctcaaatatttcaacggacacaagaagcataaaaaaaggtgat
ttatttattgcactcaagggaaggaattttgatggccataattttttgcatgaagcgttt
ttaaaaggggctgtcgctgcaatagtaagtgagggtaaatataaaaatttccctctcatt
attgtacaagataccctgaaagctttgcacgatatggcatcatactacattagaaatgtt
cttattgacgctaaagttattgcagttacaggcagtgtcggaaaaaccactacaaaggat
atgctacacactgttttatcgcaatatggagtgtcccatgcaaacgaaggtaacttaaat
aataatatagggttgcctttgacaattctaaaagctccaaaaaactgccagtacttaatc
cttgaaatgggaatgaataaagctggtgaaataaaagaattatcaaagattagtaatcca
aatattgcagttattaccaacatcgaacctgcacatactgaaaatttttcatcactattt
gacgttgcacaagcgaagttagaaattctgtatggtatgaaaaataacggtactttggtt
ttaagcagagataataaatattatgattatctctcatcacacgccaatagaaatgtaata
agcttcggtaaagataaaaatgctgaagtttgtttactaaacttaataagaaacgatgaa
tcttctgtcatttcagcactatcttctgtcatcccagtgcttgactacttggatccagga
agttcaattgcaaatgagcatatcagacggttgtataataaagactggattccagcgtca
cgcgctggaatgacatcaaaccgagttgctaatagattaagtttaaaaatcaggctgagt
gataatcaaattataaactgtaatttacgtgtacaaggtgagcattttgcttattcgcta
cttgctgttgcagcagttgtgcaaagcctcggacttgatttatcaaaattaccacttgca
cttaagaattttagtgtagcgaaaggtagaggcaatattcataagatcaaatacaataga
aaatatatacatttaattgatgactcctataacgccagccctgcttcgatgaaaactgca
ataaaaactttgagtacatattctaatcagagaaaagtagctttgcttggtgatatgttg
gaacttggtgatgaaagcatagagtttcatacagatttggttaagattatcacagaaaat
aatatagataaagtttatacagttggtaaatttatgttagaattgcatgagcttttgcca
gataatataagaggcacacattttaatgattctaatcaattgaaaagtgatttagctaac
attattcagaataatgacgcaattctagttaaaggctcacgaggaatgaaaatggatctt
attgtacgggaattcgtaataaaatattaa
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